3-(ChloroMethyl)pyridazine hydrochloride

Product Name: 3-(ChloroMethyl)pyridazine hydrochloride
CAS No.: 27349-66-2
Chemical Name: 3-(ChloroMethyl)pyridazine hydrochloride
Synonyms: 3-(CHLOROMETHYL)PYRIDAZINE HCL;3-(ChloroMethyl)pyridazine hydrochloride
CBNumber: CB12615195
Molecular Formula: C5H6Cl2N2
Formula Weight: 165.02
MOL File: 27349-66-2.mol

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3-(ChloroMethyl)pyridazine hydrochloride Property

storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
Appearance: Light brown to brown Solid

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H318Causes serious eye damage

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: C650080
Product name: 3-(chloromethyl)pyridazinehydrochloride
Packaging: 10mg
Price: $45
Updated: 2021/12/16

TRC

Product number: C650080
Product name: 3-(chloromethyl)pyridazinehydrochloride
Packaging: 100mg
Price: $285
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC141554
Product name: 3-(Chloromethyl)pyridazine hydrochloride
Packaging: 100mg
Price: $129
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC141554
Product name: 3-(Chloromethyl)pyridazine hydrochloride
Packaging: 250mg
Price: $257.5
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC141554
Product name: 3-(Chloromethyl)pyridazine hydrochloride
Packaging: 50mg
Price: $74
Updated: 2021/12/16

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3-(ChloroMethyl)pyridazine hydrochloride Chemical Properties,Usage,Production

Synthesis

1632-76-4

87-90-1

27349-66-2

Method B: Synthesis of 3-(chloromethyl)pyridazine. Trichloroisocyanuric acid (148 mg, 0.6 mmol) was added batchwise to a chloroform solution of 3-methylpyridazine (145 μL, 1.6 mmol) under reflux conditions. The reaction mixture was stirred at reflux overnight. After completion of the reaction, the mixture was cooled to room temperature and filtered. The filtrate was diluted with dichloromethane and washed sequentially with 1 M aqueous sodium hydroxide and saturated saline. The organic phase was dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give 3-(chloromethyl)pyridazine hydrochloride (205 mg, 80% yield). Mass spectrum (ESI): calculated value C5H5ClN2, 128.0; measured value m/z, 129 [M + H]+. Intermediate 3: 5-(chloromethyl)pyrimidine hydrochloride.

References

[1] Patent: WO2018/67786, 2018, A1. Location in patent: Page/Page column 103; 104

3-(ChloroMethyl)pyridazine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(ChloroMethyl)pyridazine hydrochloride Suppliers

China 34 India 1 United Kingdom 1 United States 5 Global 41

ZEROSCHEM.CO.,LTD.

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SPIRO PHARMA

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Amadis Chemical Company Limited

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Hangzhou Molcore Biopharmatech Co.,Ltd

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Shanghai SPAR pharmaceutical technology co., LTD

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Shanghai Jizhi Biochemical Technology Co. Ltd.

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27349-66-2