ChemicalBook > CAS DataBase List > 2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe
2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe
- Product Name
- 2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe
- CAS No.
- 17302-61-3
- Chemical Name
- 2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe
- Synonyms
- 1-oxime;PoloxiMe;5-Cyclohexadiene-1;2-methyl-5-(1-methylethyl)-;p-Mentha-3,6-diene-2,5-dione 2-oxime;2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe
- CBNumber
- CB12623846
- Molecular Formula
- C10H13NO2
- Formula Weight
- 179.22
- MOL File
- 17302-61-3.mol
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2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe Property
- Melting point:
- 162℃ (Decomposition)
- Boiling point:
- 296.8±33.0 °C(Predicted)
- Density
- 1.10±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 6.43±0.58(Predicted)
- form
- Powder
- color
- Light yellow to yellow
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N-Bromosuccinimide Price
TRC
- Product number
- A102086
- Product name
- Poloxime
- Packaging
- 100mg
- Price
- $220
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb611818
- Product name
- Poloxime
- Packaging
- 10mg
- Price
- $221
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-1334
- Product name
- Poloxime
- Packaging
- 5mg
- Price
- $78
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B3609
- Product name
- Poloxime
- Packaging
- 10mg
- Price
- $166
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B3609
- Product name
- Poloxime
- Packaging
- 5mg
- Price
- $103
- Updated
- 2021/12/16
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2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe Chemical Properties,Usage,Production
Biological Activity
Poloxime is a hydrolysis product of poloxin, a non-competitive ATP inhibitor of Plk1, which can properly inhibit the activity of Plk1.
in vitro
Poloxime (100 μM) inhibits phosphopeptide binding to polo-box domain (PBD) of polo-like kinase 1 (Plk1).
target
PLK1
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2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe Preparation Products And Raw materials
Raw materials
Preparation Products
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2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe Suppliers
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