ChemicalBook > CAS DataBase List > 2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe

2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe

Product Name
2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe
CAS No.
17302-61-3
Chemical Name
2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe
Synonyms
1-oxime;PoloxiMe;5-Cyclohexadiene-1;2-methyl-5-(1-methylethyl)-;p-Mentha-3,6-diene-2,5-dione 2-oxime;2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe
CBNumber
CB12623846
Molecular Formula
C10H13NO2
Formula Weight
179.22
MOL File
17302-61-3.mol
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2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe Property

Melting point:
162℃ (Decomposition)
Boiling point:
296.8±33.0 °C(Predicted)
Density 
1.10±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
6.43±0.58(Predicted)
form 
Powder
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A102086
Product name
Poloxime
Packaging
100mg
Price
$220
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611818
Product name
Poloxime
Packaging
10mg
Price
$221
Updated
2021/12/16
ChemScene
Product number
CS-1334
Product name
Poloxime
Packaging
5mg
Price
$78
Updated
2021/12/16
ApexBio Technology
Product number
B3609
Product name
Poloxime
Packaging
10mg
Price
$166
Updated
2021/12/16
ApexBio Technology
Product number
B3609
Product name
Poloxime
Packaging
5mg
Price
$103
Updated
2021/12/16
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2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe Chemical Properties,Usage,Production

Biological Activity

Poloxime is a hydrolysis product of poloxin, a non-competitive ATP inhibitor of Plk1, which can properly inhibit the activity of Plk1.

in vitro

Poloxime (100 μM) inhibits phosphopeptide binding to polo-box domain (PBD) of polo-like kinase 1 (Plk1).

target

PLK1

2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe Preparation Products And Raw materials

Raw materials

Preparation Products

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2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe Suppliers

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17302-61-3, 2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMeRelated Search:


  • 2,5-Cyclohexadiene-1,4-dione, 2-Methyl-5-(1-Methylethyl)-, 1-oxiMe
  • PoloxiMe
  • p-Mentha-3,6-diene-2,5-dione 2-oxime
  • 1-oxime
  • 2-methyl-5-(1-methylethyl)-
  • 5-Cyclohexadiene-1
  • 17302-61-3