ChemicalBook > CAS DataBase List > Rolapitant

Rolapitant

Product Name
Rolapitant
CAS No.
552292-08-7
Chemical Name
Rolapitant
Synonyms
Roltant;SCH619734;Rolapitant;Rolapitant-d4;Rolapitant HCl;brand name: Varubi;Rolapitant USP/EP/BP;SCH619734 SCH-619734;Rolapitant(sch619734);rolapitant,914462-92-3
CBNumber
CB12628366
Molecular Formula
C25H26F6N2O2
Formula Weight
500.48
MOL File
552292-08-7.mol
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Rolapitant Property

Boiling point:
523.5±50.0 °C(Predicted)
Density 
1.34±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 25 mg/ml; DMF:PBS(pH7.2) (1:2): 0.33 mg/ml; DMSO: 16 mg/ml; Ethanol: 3 mg/ml
pka
15.88±0.40(Predicted)
form 
Powder
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
23906
Product name
Rolapitant
Purity
≥98%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
23906
Product name
Rolapitant
Purity
≥98%
Packaging
5mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
23906
Product name
Rolapitant
Purity
≥98%
Packaging
10mg
Price
$214
Updated
2024/03/01
AK Scientific
Product number
3912BB
Product name
Rolapitant
Packaging
1mg
Price
$133
Updated
2021/12/16
ChemScene
Product number
CS-6387
Product name
Rolapitant
Purity
98.43%
Packaging
10mg
Price
$150
Updated
2021/12/16
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Rolapitant Chemical Properties,Usage,Production

Definition

ChEBI: An azaspiro compound that is 1,7-diazaspiro[4.5]decan-2-one carrying additional phenyl and 1-{[3,5-bis(trifluoromethyl)phenyl]ethoxy}methyl substituents at position 8. Used (in the form of the hydrochloride hydrate) for the prevention of delayed nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy.

Rolapitant Preparation Products And Raw materials

Raw materials

Preparation Products

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Rolapitant Suppliers

China 114 India 2 United Kingdom 1 United States 8 Global 125
Doly Chemical CO.,LTD.
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View Lastest Price from Rolapitant manufacturers

Hebei Duling International Trade Co. LTD
Product
Rolapitant 552292-08-7
Price
US $35.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2023-03-23
Wuhan Topule Biopharmaceutical Co., Ltd
Product
Rolapitant 552292-08-7
Price
US $8.00/g
Min. Order
1g
Purity
98%
Supply Ability
500g
Release date
2023-06-13
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
rolapitant 552292-08-7
Price
US $45.99/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2021-12-24

552292-08-7, RolapitantRelated Search:

ROLIPRAM Rolapitant (1R,2S,3R)-Isomer Rolapitant (1S,2R,3R)-Isomer Rolapitant (1S,2R,3S)-Isomer Rolapitant (1R,2R,3S)-Isomer ROLAPITANT HYDROCHLORIDE Rolapitant (1S,2S,3R)-Isomer Rolapitant (1S,2S,3S)-Isomer Rituximab Aprepitant Emtricitabine Tacrolimus Sumatriptan Memantine

  • Rolapitant
  • (5S,8S)-8-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro[4.5]decan-2-one hydrochloride.
  • Rolapitant HCl
  • Rolapitant(sch619734)
  • (5S,8S)-8-[[[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethyl]oxy]methyl]-8-phenyl-1,7-diazaspiro[4.5]decan-2-one
  • (5S,8S)-8-({(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}methyl)-8-phenyl-1,7-diazaspiro[4.5]decan-2-one
  • rolapitant,914462-92-3
  • 1,7-Diazaspiro[4.5]decan-2-one,8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-,(5S,8S)-
  • (5S,8S)-8-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-8-phenyl-1,9-diazaspiro[4.5]decan-2-one
  • Rolapitant-d4
  • SCH619734
  • Rolapitant USP/EP/BP
  • Roltant
  • 3-Tritetradecanoylglycerol
  • brand name: Varubi
  • SCH619734 SCH-619734
  • foot tapping,long-acting,emesis,retches,Rolapitant,NK receptor,Neurokinin Receptor,vomits,SCH 619734,SCH-619734,anti-emetic,Inhibitor,inhibit,orally active,Mongolian Gerbils,Tachykinin receptor,ferret
  • (5S,8S)-8-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro[4.5]decan-2-one
  • 552292-08-7
  • C25H26F6N2O2