ChemicalBook > CAS DataBase List > 2-(METHYLTHIO)PYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE

2-(METHYLTHIO)PYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE

Product Name: 2-(METHYLTHIO)PYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE
CAS No.: 902576-09-4
Chemical Name: 2-(METHYLTHIO)PYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE
Synonyms: 2-(METHYLTHIO)PYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE;2-methylsulfanyl-6h-pyrido[4,3-d]pyrimidin-5-one;Pyrido[4,3-d]pyrimidin-5(6H)-one, 2-(methylthio)-;2-(methylsulfanyl)-5H,6H-pyrido[4,3-d]pyrimidin-5-one
CBNumber: CB12646742
Molecular Formula: C8H7N3OS
Formula Weight: 193.23
MOL File: 902576-09-4.mol

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2-(METHYLTHIO)PYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE Property

storage temp.: 2-8°C
Appearance: Light yellow to yellow Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: M224018
Product name: 2-(Methylthio)pyrido[4,3-D]pyrimidin-5(6H)-one
Packaging: 10mg
Price: $45
Updated: 2021/12/16

AK Scientific

Product number: 7758DF
Product name: 2-(Methylthio)pyrido[4,3-D]pyrimidin-5(6H)-one
Packaging: 250mg
Price: $139
Updated: 2021/12/16

Ambeed

Product number: A310645
Product name: 2-(Methylthio)pyrido[4,3-d]pyrimidin-5(6H)-one
Purity: 97%
Packaging: 1g
Price: $145
Updated: 2021/12/16

Alichem

Product number: 902576094
Product name: 2-(Methylthio)pyrido[4,3-d]pyrimidin-5(6H)-one
Packaging: 250mg
Price: $168.48
Updated: 2021/12/16

Crysdot

Product number: CD11021445
Product name: 2-(Methylthio)pyrido[4,3-d]pyrimidin-5(6H)-one
Purity: 97%
Packaging: 1g
Price: $238
Updated: 2021/12/16

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2-(METHYLTHIO)PYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE Chemical Properties,Usage,Production

Synthesis

1228565-00-1

902576-09-4

General procedure for the synthesis of 2-(methylthio)pyrido[4,3-d]pyrimidin-5(6H)-ones from ethyl 4-((E)-2-(dimethylamino)vinyl)-2-(methylthio)pyrimidine-5-carboxylate: ethyl 4-((E)-2-(dimethylamino)vinyl)-2-(methylthio)pyrimidine-5-carboxylate (13.5 g, 50.5 mmol) and NH4OAc (38.9 g, 505 mmol) were dissolved in DMF (250 mL) and the reaction mixture was stirred under reflux conditions for about 4 days. Upon completion of the reaction, the mixture was concentrated, the residue was dissolved in trichloromethane (TCM), washed with water, and the organic phase was dried, filtered and concentrated. The product was purified by crystallization from ethanol to afford 2-(methylthio)pyrido[4,3-d]pyrimidin-5(6H)-one (7.60 g, 39.4 mmol, 78% yield) as a colorless solid.

References

[1] Patent: WO2010/63352, 2010, A1. Location in patent: Page/Page column 89
[2] Patent: US2013/225589, 2013, A1. Location in patent: Paragraph 0439
[3] Patent: WO2014/23385, 2014, A1. Location in patent: Page/Page column 73; 76; 77

2-(METHYLTHIO)PYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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902576-09-4, 2-(METHYLTHIO)PYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONERelated Search:

2-(METHYLTHIO)PYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE

2-(methylsulfanyl)-5H,6H-pyrido[4,3-d]pyrimidin-5-one

Pyrido[4,3-d]pyrimidin-5(6H)-one, 2-(methylthio)-

2-methylsulfanyl-6h-pyrido[4,3-d]pyrimidin-5-one

902576-09-4