ChemicalBook > CAS DataBase List > 2-(METHYLTHIO)PYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE

2-(METHYLTHIO)PYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE

Product Name
2-(METHYLTHIO)PYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE
CAS No.
902576-09-4
Chemical Name
2-(METHYLTHIO)PYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE
Synonyms
2-(METHYLTHIO)PYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE;2-methylsulfanyl-6h-pyrido[4,3-d]pyrimidin-5-one;Pyrido[4,3-d]pyrimidin-5(6H)-one, 2-(methylthio)-;2-(methylsulfanyl)-5H,6H-pyrido[4,3-d]pyrimidin-5-one
CBNumber
CB12646742
Molecular Formula
C8H7N3OS
Formula Weight
193.23
MOL File
902576-09-4.mol
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2-(METHYLTHIO)PYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE Property

storage temp. 
2-8°C
Appearance
Light yellow to yellow Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
M224018
Product name
2-(Methylthio)pyrido[4,3-D]pyrimidin-5(6H)-one
Packaging
10mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
7758DF
Product name
2-(Methylthio)pyrido[4,3-D]pyrimidin-5(6H)-one
Packaging
250mg
Price
$139
Updated
2021/12/16
Ambeed
Product number
A310645
Product name
2-(Methylthio)pyrido[4,3-d]pyrimidin-5(6H)-one
Purity
97%
Packaging
100mg
Price
$38
Updated
2021/12/16
Ambeed
Product number
A310645
Product name
2-(Methylthio)pyrido[4,3-d]pyrimidin-5(6H)-one
Purity
97%
Packaging
250mg
Price
$59
Updated
2021/12/16
Ambeed
Product number
A310645
Product name
2-(Methylthio)pyrido[4,3-d]pyrimidin-5(6H)-one
Purity
97%
Packaging
1g
Price
$145
Updated
2021/12/16
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2-(METHYLTHIO)PYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE Chemical Properties,Usage,Production

Synthesis

1228565-00-1

902576-09-4

General procedure for the synthesis of 2-(methylthio)pyrido[4,3-d]pyrimidin-5(6H)-ones from ethyl 4-((E)-2-(dimethylamino)vinyl)-2-(methylthio)pyrimidine-5-carboxylate: ethyl 4-((E)-2-(dimethylamino)vinyl)-2-(methylthio)pyrimidine-5-carboxylate (13.5 g, 50.5 mmol) and NH4OAc (38.9 g, 505 mmol) were dissolved in DMF (250 mL) and the reaction mixture was stirred under reflux conditions for about 4 days. Upon completion of the reaction, the mixture was concentrated, the residue was dissolved in trichloromethane (TCM), washed with water, and the organic phase was dried, filtered and concentrated. The product was purified by crystallization from ethanol to afford 2-(methylthio)pyrido[4,3-d]pyrimidin-5(6H)-one (7.60 g, 39.4 mmol, 78% yield) as a colorless solid.

References

[1] Patent: WO2010/63352, 2010, A1. Location in patent: Page/Page column 89
[2] Patent: US2013/225589, 2013, A1. Location in patent: Paragraph 0439
[3] Patent: WO2014/23385, 2014, A1. Location in patent: Page/Page column 73; 76; 77

2-(METHYLTHIO)PYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(METHYLTHIO)PYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE Suppliers

China 39 India 1 United States 3 Global 43
A.J Chemicals
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sales@ajchem.in
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India
ProdList
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902576-09-4, 2-(METHYLTHIO)PYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONERelated Search:


  • 2-(METHYLTHIO)PYRIDO[4,3-D]PYRIMIDIN-5(6H)-ONE
  • 2-(methylsulfanyl)-5H,6H-pyrido[4,3-d]pyrimidin-5-one
  • Pyrido[4,3-d]pyrimidin-5(6H)-one, 2-(methylthio)-
  • 2-methylsulfanyl-6h-pyrido[4,3-d]pyrimidin-5-one
  • 902576-09-4