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Adelmidrol

Product Name
Adelmidrol
CAS No.
1675-66-7
Chemical Name
Adelmidrol
Synonyms
Demiqu;NSC 27132;Adelmidrol;AdelMitrol;AdelMitrol USP/EP/BP;Adelmidrol, 10 mM in DMSO;N,N'-Bis(2-hydroxyethyl)nonanediamide;N1,N9-bis(2-hydroxyethyl)-nonanediamide;Nonanediamide, N1,N9-bis(2-hydroxyethyl)-;China biggest manufacturer,AdelMitrol,1675-66-7
CBNumber
CB12657232
Molecular Formula
C13H26N2O4
Formula Weight
274.36
MOL File
1675-66-7.mol
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Adelmidrol Property

Melting point:
132-134℃
Boiling point:
596.4±45.0 °C(Predicted)
Density 
1.097±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO:77.5(Max Conc. mg/mL);282.47(Max Conc. mM)
Ethanol:28.0(Max Conc. mg/mL);102.06(Max Conc. mM)
Water:55.0(Max Conc. mg/mL);200.47(Max Conc. mM)
pka
14.19±0.10(Predicted)
form 
Solid
color 
White to off-white
InChI
InChI=1S/C13H26N2O4/c16-10-8-14-12(18)6-4-2-1-3-5-7-13(19)15-9-11-17/h16-17H,1-11H2,(H,14,18)(H,15,19)
InChIKey
PAHZPHDAJQIETD-UHFFFAOYSA-N
SMILES
C(NCCO)(=O)CCCCCCCC(NCCO)=O
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A247540
Product name
Adelmidrol
Packaging
25mg
Price
$65
Updated
2021/12/16
ChemScene
Product number
CS-4543
Product name
Adelmidrol
Purity
≥98.0%
Packaging
100mg
Price
$72
Updated
2021/12/16
AK Scientific
Product number
1760CB
Product name
Adelmidrol
Packaging
1g
Price
$848
Updated
2021/12/16
DC Chemicals
Product number
DC10745
Product name
Adelmidrol
Purity
>98%
Packaging
1g
Price
$800
Updated
2021/12/16
Ambeed
Product number
A103800
Product name
Adelmidrol
Purity
98+%
Packaging
25mg
Price
$24
Updated
2021/12/16
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Adelmidrol Chemical Properties,Usage,Production

Description

N,N'-Bis(2-hydroxyethyl)nonanediamide, also named Admidol, is an anti-inflammatory ethanolamide derivative. It is hydrophilic and hydrophobic, favoring its solubility in water and organic media. As an naturally occurring saturated dicarboxylic acid, it is found in trace amounts in the human body and in some whole grains. Adelmidrol is an analogue of palmitoylethanolamide (PEA), which is a well-known anti-inflammatory and anti-oxidant compound.  Adelmidrol  was able to manage the significant incapacity of antioxidants and elevation of the oxidant burden[1-2].

Uses

Adelmidrol is an anti-inflammatory. It can be used in biological study of protective effect of adelmidrol as new palmitoylethanolamide analog for pharmacol. treatment of inflammatory bowel disease in mouse model.

Biological Activity

Adelmidrol is an analog of hexadecylamide ethanol (PEA) with anti-inflammatory activity.

in vitro

Adelmidrol is a palmitoylethanolamide analogue. Adelmidrol reduces NF-κB translocation, COX-2, and p-ERK expression; proinflammatory cytokine release; and the incidence of nitrotyrosine and poly(ADP)ribose in the colon.

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target

NF-κB

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COX-2

PPARγ

References

[1] Cordaro M, et al. Adelmidrol, a Palmitoylethanolamide Analogue, as a New Pharmacological Treatment for the Management of Inflammatory Bowel Disease. BIOCHEMICAL PHARMACOLOGY, 2016; 90: 549-561
[2] Fusco R, et al. Adelmidrol: A New Promising Antioxidant and Anti-Inflammatory Therapeutic Tool in Pulmonary Fibrosis. Antioxidants, 2020; 9.
[3] Guida F, et al. Targeting Neuroinflammation in Osteoarthritis with Intra-Articular Adelmidrol. 2022; 12.

Adelmidrol Preparation Products And Raw materials

Raw materials

Preparation Products

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Adelmidrol Suppliers

Henan Vcommend Consultrading Co., Ltd.
Tel
13393721940; 13393721940
Email
sales@vcommend.com
Country
China
ProdList
10005
Advantage
58
Hubei Weideli Chemical Reagent Co.,Ltd.
Tel
027-59222918 13385289472
Email
Z13385289472@163.com
Country
China
ProdList
4921
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19915
Advantage
55
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
GIHI CHEMICALS CO.,LTD
Tel
0086-571-86217390
Fax
0086-571-86217391
Email
Sales@gihichem.com
Country
China
ProdList
860
Advantage
58
Conier Chem & Pharma Co.,Ltd,
Tel
023-62879767 13996269627;
Fax
+86-28-84559521
Email
sales@conier.com
Country
China
ProdList
300
Advantage
56
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4573
Advantage
55
Puripharm Co., Ltd.
Tel
0572-2745768-1 13167223168
Fax
13167223168
Email
sales@puripharm.com
Country
China
ProdList
299
Advantage
65
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
5944
Advantage
55
Shanghai SuperLan Chemcial Technique Centre
Tel
021-2022843681 15618226720
Fax
+86-21-51601218
Email
lucy@atkchemical.com
Country
China
ProdList
9987
Advantage
58
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View Lastest Price from Adelmidrol manufacturers

Dideu Industries Group Limited
Product
AdelMitrol 1675-66-7
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-08-16
Career Henan Chemical Co
Product
AdelMitrol 1675-66-7
Price
US $1.00/KG
Min. Order
1KG
Purity
97%-99.9%
Supply Ability
100kg
Release date
2019-12-25
GIHI CHEMICALS CO.,LIMITED
Product
Adelmitrol 1675-66-7
Price
US $0.00/KG
Min. Order
1g
Purity
99%
Supply Ability
1ton
Release date
2019-01-31

1675-66-7, AdelmidrolRelated Search:


  • AdelMitrol
  • N,N'-Bis(2-hydroxyethyl)nonanediamide
  • NSC 27132
  • Nonanediamide, N1,N9-bis(2-hydroxyethyl)-
  • AdelMitrol USP/EP/BP
  • N1,N9-bis(2-hydroxyethyl)-nonanediamide
  • China biggest manufacturer,AdelMitrol,1675-66-7
  • Demiqu
  • NF-κB,Nuclear factor-kappaB,PPAR,COX,Adelmidrol,Cyclooxygenase,Peroxisome proliferator-activated receptors,inhibit,Inhibitor,Nuclear factor-κB
  • Adelmidrol
  • Adelmidrol, 10 mM in DMSO
  • 1675-66-7