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Adelmidrol

Product Name: Adelmidrol
CAS No.: 1675-66-7
Chemical Name: Adelmidrol
Synonyms: Demiqu;NSC 27132;Adelmidrol;AdelMitrol;AdelMitrol USP/EP/BP;Adelmidrol, 10 mM in DMSO;N,N'-Bis(2-hydroxyethyl)nonanediamide;N1,N9-bis(2-hydroxyethyl)-nonanediamide;Nonanediamide, N1,N9-bis(2-hydroxyethyl)-;China biggest manufacturer,AdelMitrol,1675-66-7
CBNumber: CB12657232
Molecular Formula: C13H26N2O4
Formula Weight: 274.36
MOL File: 1675-66-7.mol

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Adelmidrol Property

Melting point:: 132-134℃
Boiling point:: 596.4±45.0 °C(Predicted)
Density: 1.097±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO:77.5(Max Conc. mg/mL);282.47(Max Conc. mM)
Ethanol:28.0(Max Conc. mg/mL);102.06(Max Conc. mM)
Water:55.0(Max Conc. mg/mL);200.47(Max Conc. mM)
pka: 14.19±0.10(Predicted)
form: Solid
color: White to off-white
InChI: InChI=1S/C13H26N2O4/c16-10-8-14-12(18)6-4-2-1-3-5-7-13(19)15-9-11-17/h16-17H,1-11H2,(H,14,18)(H,15,19)
InChIKey: PAHZPHDAJQIETD-UHFFFAOYSA-N
SMILES: C(NCCO)(=O)CCCCCCCC(NCCO)=O

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: A247540
Product name: Adelmidrol
Packaging: 25mg
Price: $65
Updated: 2021/12/16

ChemScene

Product number: CS-4543
Product name: Adelmidrol
Purity: ≥98.0%
Packaging: 100mg
Price: $72
Updated: 2021/12/16

AK Scientific

Product number: 1760CB
Product name: Adelmidrol
Packaging: 1g
Price: $848
Updated: 2021/12/16

DC Chemicals

Product number: DC10745
Product name: Adelmidrol
Purity: >98%
Packaging: 1g
Price: $800
Updated: 2021/12/16

Ambeed

Product number: A103800
Product name: Adelmidrol
Purity: 98+%
Packaging: 25mg
Price: $24
Updated: 2021/12/16

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Adelmidrol Chemical Properties,Usage,Production

Description

N,N'-Bis(2-hydroxyethyl)nonanediamide, also named Admidol, is an anti-inflammatory ethanolamide derivative. It is hydrophilic and hydrophobic, favoring its solubility in water and organic media. As an naturally occurring saturated dicarboxylic acid, it is found in trace amounts in the human body and in some whole grains. Adelmidrol is an analogue of palmitoylethanolamide (PEA), which is a well-known anti-inflammatory and anti-oxidant compound. Adelmidrol was able to manage the significant incapacity of antioxidants and elevation of the oxidant burden[1-2].

Uses

Adelmidrol is an anti-inflammatory. It can be used in biological study of protective effect of adelmidrol as new palmitoylethanolamide analog for pharmacol. treatment of inflammatory bowel disease in mouse model.

Biological Activity

Adelmidrol is an analog of hexadecylamide ethanol (PEA) with anti-inflammatory activity.

in vitro

Adelmidrol is a palmitoylethanolamide analogue. Adelmidrol reduces NF-κB translocation, COX-2, and p-ERK expression; proinflammatory cytokine release; and the incidence of nitrotyrosine and poly(ADP)ribose in the colon.

target

NF-κB

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COX-2

PPARγ

References

[1] Cordaro M, et al. Adelmidrol, a Palmitoylethanolamide Analogue, as a New Pharmacological Treatment for the Management of Inflammatory Bowel Disease. BIOCHEMICAL PHARMACOLOGY, 2016; 90: 549-561
[2] Fusco R, et al. Adelmidrol: A New Promising Antioxidant and Anti-Inflammatory Therapeutic Tool in Pulmonary Fibrosis. Antioxidants, 2020; 9.
[3] Guida F, et al. Targeting Neuroinflammation in Osteoarthritis with Intra-Articular Adelmidrol. 2022; 12.

Adelmidrol Preparation Products And Raw materials

Raw materials

Preparation Products

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Adelmidrol Suppliers

China 66 India 1 United States 7 Global 74

Henan Vcommend Consultrading Co., Ltd.

Tel: 13393721940
Email: sales@vcommend.com
Country: China
ProdList: 9963
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19906
Advantage: 55

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

GIHI CHEMICALS CO.,LTD

Tel: 0086-571-86217390
Fax: 0086-571-86217391
Email: Sales@gihichem.com
Country: China
ProdList: 860
Advantage: 58

Conier Chem & Pharma Co.,Ltd,

Tel: 023-62879767 13996269627;
Fax: +86-28-84559521
Email: sales@conier.com
Country: China
ProdList: 285
Advantage: 56

Bide Pharmatech Ltd.

Tel: 400-400-164-7117 18317119277
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 40000
Advantage: 60

Shanghai Lollane Biological Technology Co.,Ltd.

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Country: China
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Puripharm Co., Ltd.

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Shanghai YuanYe Biotechnology Co., Ltd.

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ProdList: 71826
Advantage: 60

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 9365
Advantage: 55

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View Lastest Price from Adelmidrol manufacturers

Dideu Industries Group Limited

Product: AdelMitrol 1675-66-7
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-08-16

Career Henan Chemical Co

Product: AdelMitrol 1675-66-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 97%-99.9%
Supply Ability: 100kg
Release date: 2019-12-25

GIHI CHEMICALS CO.,LIMITED

Product: Adelmitrol 1675-66-7
Price: US $0.00/KG
Min. Order: 1g
Purity: 99%
Supply Ability: 1ton
Release date: 2019-01-31

1675-66-7, AdelmidrolRelated Search:

AdelMitrol

N,N'-Bis(2-hydroxyethyl)nonanediamide

NSC 27132

Nonanediamide, N1,N9-bis(2-hydroxyethyl)-

AdelMitrol USP/EP/BP

N1,N9-bis(2-hydroxyethyl)-nonanediamide

China biggest manufacturer,AdelMitrol,1675-66-7

Demiqu

NF-κB,Nuclear factor-kappaB,PPAR,COX,Adelmidrol,Cyclooxygenase,Peroxisome proliferator-activated receptors,inhibit,Inhibitor,Nuclear factor-κB

Adelmidrol

Adelmidrol, 10 mM in DMSO

1675-66-7