AdelMitrol

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Product Name: AdelMitrol
CAS No.: 1675-66-7
Chemical Name: AdelMitrol
Synonyms: Demiqu;NSC 27132;AdelMitrol;AdelMitrol USP/EP/BP;N,N'-Bis(2-hydroxyethyl)nonanediamide;N1,N9-bis(2-hydroxyethyl)-nonanediamide;Nonanediamide, N1,N9-bis(2-hydroxyethyl)-;China biggest manufacturer,AdelMitrol,1675-66-7;NF-κB,Nuclear factor-kappaB,PPAR,COX,Adelmidrol,Cyclooxygenase,Peroxisome proliferator-activated receptors,inhibit,Inhibitor,Nuclear factor-κB
CBNumber: CB12657232
Molecular Formula: C13H26N2O4
Formula Weight: 274.36
MOL File: 1675-66-7.mol

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AdelMitrol Property

Melting point:: 132-134℃
Boiling point:: 596.4±45.0 °C(Predicted)
Density: 1.097±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO:77.5(Max Conc. mg/mL);282.47(Max Conc. mM)
Ethanol:28.0(Max Conc. mg/mL);102.06(Max Conc. mM)
Water:55.0(Max Conc. mg/mL);200.47(Max Conc. mM)
pka: 14.19±0.10(Predicted)
InChI: InChI=1S/C13H26N2O4/c16-10-8-14-12(18)6-4-2-1-3-5-7-13(19)15-9-11-17/h16-17H,1-11H2,(H,14,18)(H,15,19)
InChIKey: PAHZPHDAJQIETD-UHFFFAOYSA-N
SMILES: C(NCCO)(=O)CCCCCCCC(NCCO)=O

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: A247540
Product name: Adelmidrol
Packaging: 25mg
Price: $65
Updated: 2021/12/16

ChemScene

Product number: CS-4543
Product name: Adelmidrol
Purity: ≥98.0%
Packaging: 100mg
Price: $72
Updated: 2021/12/16

AK Scientific

Product number: 1760CB
Product name: Adelmidrol
Packaging: 1g
Price: $848
Updated: 2021/12/16

DC Chemicals

Product number: DC10745
Product name: Adelmidrol
Purity: >98%
Packaging: 1g
Price: $800
Updated: 2021/12/16

Ambeed

Product number: A103800
Product name: Adelmidrol
Purity: 98+%
Packaging: 25mg
Price: $24
Updated: 2021/12/16

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AdelMitrol Chemical Properties,Usage,Production

Description

N,N'-Bis(2-hydroxyethyl)nonanediamide, also named Admidol, is an anti-inflammatory ethanolamide derivative. It is hydrophilic and hydrophobic, favoring its solubility in water and organic media. As an naturally occurring saturated dicarboxylic acid, it is found in trace amounts in the human body and in some whole grains. Adelmidrol is an analogue of palmitoylethanolamide (PEA), which is a well-known anti-inflammatory and anti-oxidant compound. Adelmidrol was able to manage the significant incapacity of antioxidants and elevation of the oxidant burden[1-2].

Uses

Adelmidrol is an anti-inflammatory. It can be used in biological study of protective effect of adelmidrol as new palmitoylethanolamide analog for pharmacol. treatment of inflammatory bowel disease in mouse model.

Biological Activity

Adelmidrol is an analog of hexadecylamide ethanol (PEA) with anti-inflammatory activity.

in vitro

Adelmidrol is a palmitoylethanolamide analogue. Adelmidrol reduces NF-κB translocation, COX-2, and p-ERK expression; proinflammatory cytokine release; and the incidence of nitrotyrosine and poly(ADP)ribose in the colon.

target

NF-κB

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COX-2

PPARγ

References

[1] Cordaro M, et al. Adelmidrol, a Palmitoylethanolamide Analogue, as a New Pharmacological Treatment for the Management of Inflammatory Bowel Disease. BIOCHEMICAL PHARMACOLOGY, 2016; 90: 549-561
[2] Fusco R, et al. Adelmidrol: A New Promising Antioxidant and Anti-Inflammatory Therapeutic Tool in Pulmonary Fibrosis. Antioxidants, 2020; 9.
[3] Guida F, et al. Targeting Neuroinflammation in Osteoarthritis with Intra-Articular Adelmidrol. 2022; 12.

AdelMitrol Preparation Products And Raw materials

Raw materials

Preparation Products

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AdelMitrol Suppliers

China 51 India 1 United States 6 Global 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66099280 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19918
Advantage: 55

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7553
Advantage: 61

GIHI CHEMICALS CO.,LTD

Tel: 0086-571-86217390
Fax: 0086-571-86217391
Email: Sales@gihichem.com
Country: China
ProdList: 861
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4121
Advantage: 55

Puripharm Co., Ltd.

Tel: 0572-2745768-1 13167223168
Fax: 13167223168
Email: sales@puripharm.com
Country: China
ProdList: 281
Advantage: 65

Tianjin Kailiqi Biotechnology Co., Ltd.

Tel: 15076683720
Fax: 022-23754520
Email: klq@cw-bio.com
Country: China
ProdList: 3444
Advantage: 55

Shanghai Chaolan Chemical Technology Center

Tel: QQ:65489617 15618227136
Fax: 21-5161 9052
Email: info@SuperLan-chem.com
Country: China
ProdList: 9440
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131981
Advantage: 58

Medi-tech Bioscientific Co., Ltd.

Tel: 0519-83246372 13585352506
Fax: 0519-83246372
Country: China
ProdList: 1844
Advantage: 58

Chuzhou KeMail Chemical Technology Co., Ltd

Tel: 0550-5196001 15000891977
Fax: 0550-5196001
Email: wj520wjxby@126.com
Country: China
ProdList: 1831
Advantage: 55

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View Lastest Price from AdelMitrol manufacturers

Dideu Industries Group Limited

Product: AdelMitrol 1675-66-7
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-08-16

Career Henan Chemical Co

Product: AdelMitrol 1675-66-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 97%-99.9%
Supply Ability: 100kg
Release date: 2019-12-25

GIHI CHEMICALS CO.,LIMITED

Product: Adelmitrol 1675-66-7
Price: US $0.00/KG
Min. Order: 1g
Purity: 99%
Supply Ability: 1ton
Release date: 2019-01-31

1675-66-7, AdelMitrolRelated Search:

AdelMitrol

N,N'-Bis(2-hydroxyethyl)nonanediamide

NSC 27132

Nonanediamide, N1,N9-bis(2-hydroxyethyl)-

AdelMitrol USP/EP/BP

N1,N9-bis(2-hydroxyethyl)-nonanediamide

China biggest manufacturer,AdelMitrol,1675-66-7

Demiqu

NF-κB,Nuclear factor-kappaB,PPAR,COX,Adelmidrol,Cyclooxygenase,Peroxisome proliferator-activated receptors,inhibit,Inhibitor,Nuclear factor-κB

1675-66-7