FTI-277

ChemicalBook > CAS DataBase List > FTI-277

Product Name: FTI-277
CAS No.: 170006-73-2
Chemical Name: FTI-277
Synonyms: FTI-277;FTI-277;FTI277;METHYL[N-[2-PHENYL-4-N-[2(R)-AMINO-3-MERCAPTOPROPYLAMINO] BENZOYL]]-METHIONATE, TFA;N-[[5-[[(2R)-2-Amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-L-methionine methyl ester;N-[4-[2(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE METHYL ESTER TRIFLUOROACETATE SALT;L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-, methyl ester;N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine methyl ester trifluoroacetate salt
CBNumber: CB1266050
Molecular Formula: C22H29N3O3S2
Formula Weight: 447.61
MOL File: 170006-73-2.mol

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FTI-277 Property

Boiling point:: 684.2±55.0 °C(Predicted)
Density: 1.222±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: H₂O: soluble
form: amorphous semi-solid
pka: 9.81±0.10(Predicted)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: F9803
Product name: FTI-277 trifluoroacetate salt
Purity: ≥95% (HPLC), amorphous semi-solid
Packaging: 1mg
Price: $190
Updated: 2024/03/01

Sigma-Aldrich

Product number: F9803
Product name: FTI-277 trifluoroacetate salt
Purity: ≥95% (HPLC), amorphous semi-solid
Packaging: 5mg
Price: $697
Updated: 2024/03/01

Tocris

Product number: 2407
Product name: FTI277
Purity: ≥95%(HPLC)
Packaging: 1
Price: $148
Updated: 2021/12/16

Usbiological

Product number: 255341
Product name: FTI 277
Packaging: 1mg
Price: $389
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0003962
Product name: FTI-277
Purity: 95.00%
Packaging: 5MG
Price: $501.88
Updated: 2021/12/16

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FTI-277 Chemical Properties,Usage,Production

Uses

Farnesyltransferase inhibitor 277 (FTI-277) has been used to:

inhibit protein farnesylation in breast cell lines.
in marrow-isolated adult multilineage inducible cells (MIAMI).
inhibition of farnesyl transferase in CV-1 in Origin with SV40 genes cells (COS-7).

Biochem/physiol Actions

Farnesyltransferase inhibitor 277 (FTI-277) mediates apoptosis in multiple myeloma and is regarded as a potential therapeutic agent.

FTI-277 Preparation Products And Raw materials

Raw materials

Preparation Products

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FTI-277 Suppliers

China 43 Japan 1 Switzerland 1 United Kingdom 4 United States 11 Global 60

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View Lastest Price from FTI-277 manufacturers

Career Henan Chemical Co

Product: FTI-277 trifluoroacetate salt 170006-73-2
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-09

170006-73-2, FTI-277Related Search:

METHYL[N-[2-PHENYL-4-N-[2(R)-AMINO-3-MERCAPTOPROPYLAMINO] BENZOYL]]-METHIONATE, TFA

FTI-277

N-[4-[2(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE METHYL ESTER TRIFLUOROACETATE SALT

N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine methyl ester trifluoroacetate salt

N-[[5-[[(2R)-2-Amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-L-methionine methyl ester

FTI-277;FTI277

L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-, methyl ester

170006-73-2

C22H29N3O3S2

C22H29N3O3S2C2HF3O2