ChemicalBook > CAS DataBase List > FTI-277

FTI-277

Product Name
FTI-277
CAS No.
170006-73-2
Chemical Name
FTI-277
Synonyms
FTI-277;FTI-277;FTI277;METHYL[N-[2-PHENYL-4-N-[2(R)-AMINO-3-MERCAPTOPROPYLAMINO] BENZOYL]]-METHIONATE, TFA;N-[[5-[[(2R)-2-Amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-L-methionine methyl ester;N-[4-[2(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE METHYL ESTER TRIFLUOROACETATE SALT;L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-, methyl ester;N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine methyl ester trifluoroacetate salt
CBNumber
CB1266050
Molecular Formula
C22H29N3O3S2
Formula Weight
447.61
MOL File
170006-73-2.mol
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FTI-277 Property

Boiling point:
684.2±55.0 °C(Predicted)
Density 
1.222±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
H2O: soluble
form 
amorphous semi-solid
pka
9.81±0.10(Predicted)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
F9803
Product name
FTI-277 trifluoroacetate salt
Purity
≥95% (HPLC), amorphous semi-solid
Packaging
1mg
Price
$190
Updated
2024/03/01
Sigma-Aldrich
Product number
F9803
Product name
FTI-277 trifluoroacetate salt
Purity
≥95% (HPLC), amorphous semi-solid
Packaging
5mg
Price
$697
Updated
2024/03/01
Tocris
Product number
2407
Product name
FTI277
Purity
≥95%(HPLC)
Packaging
1
Price
$148
Updated
2021/12/16
Usbiological
Product number
255341
Product name
FTI 277
Packaging
1mg
Price
$389
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0003962
Product name
FTI-277
Purity
95.00%
Packaging
5MG
Price
$501.88
Updated
2021/12/16
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FTI-277 Chemical Properties,Usage,Production

Uses

Farnesyltransferase inhibitor 277 (FTI-277) has been used to:

  • inhibit protein farnesylation in breast cell lines.
  • in marrow-isolated adult multilineage inducible cells (MIAMI).
  • inhibition of farnesyl transferase in CV-1 in Origin with SV40 genes cells (COS-7).

Biochem/physiol Actions

Farnesyltransferase inhibitor 277 (FTI-277) mediates apoptosis in multiple myeloma and is regarded as a potential therapeutic agent.

FTI-277 Preparation Products And Raw materials

Raw materials

Preparation Products

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FTI-277 Suppliers

China 43 Japan 1 Switzerland 1 United Kingdom 4 United States 11 Global 60
SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from FTI-277 manufacturers

Career Henan Chemical Co
Product
FTI-277 trifluoroacetate salt 170006-73-2
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
200kg
Release date
2020-01-09

170006-73-2, FTI-277Related Search:


  • METHYL[N-[2-PHENYL-4-N-[2(R)-AMINO-3-MERCAPTOPROPYLAMINO] BENZOYL]]-METHIONATE, TFA
  • FTI-277
  • N-[4-[2(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-PHENYLBENZOYL]METHIONINE METHYL ESTER TRIFLUOROACETATE SALT
  • N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine methyl ester trifluoroacetate salt
  • N-[[5-[[(2R)-2-Amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-L-methionine methyl ester
  • FTI-277;FTI277
  • L-Methionine, N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-, methyl ester
  • 170006-73-2
  • C22H29N3O3S2
  • C22H29N3O3S2C2HF3O2