KN93 hydrochloride
- Product Name
- KN93 hydrochloride
- CAS No.
- 1956426-56-4
- Chemical Name
- KN93 hydrochloride
- Synonyms
- CS-1449;KN-93 HCl;KN-93-HCI;KN-93 HCI;KN93 (HCI);KN-93 (HCI);KN93 hydrochloride;KN 93 hydrochloride;KN-93 (hydrochloride)
- CBNumber
- CB12666647
- Molecular Formula
- C26H30Cl2N2O4S
- Formula Weight
- 537.5
- MOL File
- 1956426-56-4.mol
KN93 hydrochloride Property
- storage temp.
- Store at -20°C
- solubility
- DMF:10.0(Max Conc. mg/mL);18.6(Max Conc. mM)
DMSO:20.5(Max Conc. mg/mL);38.14(Max Conc. mM)
Water:0.45(Max Conc. mg/mL);0.84(Max Conc. mM) - form
- A crystalline solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 13864
- Product name
- KN-93 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $107
- Updated
- 2024/03/01
- Product number
- 13864
- Product name
- KN-93 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $471
- Updated
- 2024/03/01
- Product number
- 13864
- Product name
- KN-93 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $836
- Updated
- 2024/03/01
- Product number
- orb611908
- Product name
- KN-93 HCl
- Purity
- >98%
- Packaging
- 100mg
- Price
- $646
- Updated
- 2021/12/16
- Product number
- CS-1561
- Product name
- KN-93hydrochloride
- Purity
- 99.43%
- Packaging
- 50mg
- Price
- $720
- Updated
- 2021/12/16
KN93 hydrochloride Chemical Properties,Usage,Production
Biological Activity
KN93 hydrochloride is a cell-permeable, reversible and competitive inhibitor of calmodulin-dependent kinase type II (CaMKII) with Ki of 370 nM.
in vitro
After 2 days of KN-93 treatment, 95% of cells are arrested in G1. G1 arrest is reversible; 1 day after KN93 release, a peak of cells had progressed into S and G2-M. KN93 also blocks cell growth stimulated by basic fibroblast growth factor, platelet-derived growth factor-BB, and epidermal growth factor in NIH 3T3 fibroblasts.
target
Ki: 370 nM (CaMK-II)
KN93 hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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