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KN93 hydrochloride

Product Name
KN93 hydrochloride
CAS No.
1956426-56-4
Chemical Name
KN93 hydrochloride
Synonyms
CS-1449;KN-93 HCl;KN-93-HCI;KN-93 HCI;KN93 (HCI);KN-93 (HCI);KN93 hydrochloride;KN 93 hydrochloride;KN-93 (hydrochloride);N-(2-(((3-(4-Chlorophenyl)allyl)(methyl)amino)methyl)phenyl)-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide hydrochloride
CBNumber
CB12666647
Molecular Formula
C26H30Cl2N2O4S
Formula Weight
537.5
MOL File
1956426-56-4.mol
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KN93 hydrochloride Property

storage temp. 
Store at -20°C
solubility 
DMF:10.0(Max Conc. mg/mL);18.6(Max Conc. mM)
DMSO:20.5(Max Conc. mg/mL);38.14(Max Conc. mM)
Water:0.45(Max Conc. mg/mL);0.84(Max Conc. mM)
form 
A crystalline solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
13864
Product name
KN-93 (hydrochloride)
Purity
≥98%
Packaging
1mg
Price
$107
Updated
2024/03/01
Cayman Chemical
Product number
13864
Product name
KN-93 (hydrochloride)
Purity
≥98%
Packaging
5mg
Price
$471
Updated
2024/03/01
Cayman Chemical
Product number
13864
Product name
KN-93 (hydrochloride)
Purity
≥98%
Packaging
10mg
Price
$836
Updated
2024/03/01
Biorbyt Ltd
Product number
orb611908
Product name
KN-93 HCl
Purity
>98%
Packaging
100mg
Price
$646
Updated
2021/12/16
ChemScene
Product number
CS-1561
Product name
KN-93hydrochloride
Purity
99.43%
Packaging
50mg
Price
$720
Updated
2021/12/16
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KN93 hydrochloride Chemical Properties,Usage,Production

Biological Activity

KN93 hydrochloride is a cell-permeable, reversible and competitive inhibitor of calmodulin-dependent kinase type II (CaMKII) with Ki of 370 nM.

in vitro

After 2 days of KN-93 treatment, 95% of cells are arrested in G1. G1 arrest is reversible; 1 day after KN93 release, a peak of cells had progressed into S and G2-M. KN93 also blocks cell growth stimulated by basic fibroblast growth factor, platelet-derived growth factor-BB, and epidermal growth factor in NIH 3T3 fibroblasts.

target

Ki: 370 nM (CaMK-II)

KN93 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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KN93 hydrochloride Suppliers

MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
Advantage
60
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
Cckinase, Inc.
Tel
+1 (732)236-3202
Email
sales@cckinase.com
Country
United States
ProdList
2738
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52924
Advantage
58
ApexBio Technology
Tel
--
Fax
--
Email
sales@apexbt.com
Country
United States
ProdList
6251
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58

1956426-56-4, KN93 hydrochlorideRelated Search:


  • KN 93 hydrochloride
  • KN-93 (hydrochloride)
  • KN93 hydrochloride
  • KN-93 HCl
  • CS-1449
  • KN93 (HCI)
  • KN-93 (HCI)
  • KN-93 HCI
  • KN-93-HCI
  • N-[2-[[[3-(4-chlorophenyl)-2-propen-1-yl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxy-benzenesulfonamide, monohydrochloride
  • N-(2-(((3-(4-Chlorophenyl)allyl)(methyl)amino)methyl)phenyl)-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide hydrochloride
  • 1956426-56-4
  • C26H30Cl2N2O4S