ChemicalBook > CAS DataBase List > ((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone

((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone

Product Name
((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone
CAS No.
1103738-19-7
Chemical Name
((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone
Synonyms
SOTA-005;EOS-61383;LX-4211 int;6aS)-6-hydroxy-2;LX-4211 inermediate;LX-4211 intermediate;2-dimethyltetrahydrofuro[2;D-xylo-Pentodialdo-5,2-furanose;3]dioxol-5-yl)(morpholino)methanone;LX-4211 intermediate, 10 mM in DMSO
CBNumber
CB12668005
Molecular Formula
C12H19NO6
Formula Weight
273.28
MOL File
1103738-19-7.mol
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((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone Property

Boiling point:
479.3±45.0 °C(Predicted)
Density 
1.318±0.06 g/cm3(Predicted)
pka
12.78±0.60(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-M2126
Product name
D-xylo-Pentodialdo-5,2-furanose,4,5-O-(1-methylethylidene)-1-C-4-morpholinyl-,(5S)-
Purity
99.88%
Packaging
100mg
Price
$68
Updated
2021/12/16
ChemScene
Product number
CS-M2126
Product name
D-xylo-Pentodialdo-5,2-furanose,4,5-O-(1-methylethylidene)-1-C-4-morpholinyl-,(5S)-
Purity
99.88%
Packaging
250mg
Price
$111
Updated
2021/12/16
ChemScene
Product number
CS-M2126
Product name
D-xylo-Pentodialdo-5,2-furanose,4,5-O-(1-methylethylidene)-1-C-4-morpholinyl-,(5S)-
Purity
99.88%
Packaging
1g
Price
$187
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CRB0006511
Product name
D-XYLO-PENTODIALDO-5,2-FURANOSE, 4,5-O-(1-METHYLETHYLIDENE)-1-C-4-MORPHOLINYL-,(5S)-
Purity
95.00%
Packaging
5MG
Price
$499.43
Updated
2021/12/16
ChemScene
Product number
CS-M2126
Product name
D-xylo-Pentodialdo-5,2-furanose,4,5-O-(1-methylethylidene)-1-C-4-morpholinyl-,(5S)-
Purity
99.88%
Packaging
5g
Price
$562
Updated
2021/12/16
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((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone Chemical Properties,Usage,Production

Synthesis

To a solution of (3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole-5-carboxylic acid (5.0 g, 24.5 mmol) in THF (100 ML, 20.x.) was added TBTU (11.8 g, 1.5 equiv), N-methylmorpholine (NMM, 4.1 mL, 1.5 equiv) and the mixture was stirred at 20° C. for 30 min. Morpholine (3.2 mL, 1.5 equiv) was added, and the reaction mixture was stirred at 20° C. for an additional 6h. The solid was filtered off by filtration, and the cake was washed with THF (10 mL, 2.x. .x.2). The organic solution was concentrated under a vacuum. The residue was purified by silica gel column chromatography (hexanes: EtOAc, from 1:4 to 4: 1) to afford 4.3 g of the desired morpholine amide (((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone) as a white solid.

((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone Preparation Products And Raw materials

Raw materials

Preparation Products

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((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone Suppliers

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View Lastest Price from ((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone manufacturers

Nanjing Fred Technology Co., Ltd
Product
((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone 1103738-19-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1 ton
Release date
2024-01-04
Hangzhou ICH Biofarm Co., Ltd
Product
(3aS,5R,6S,6aS)-[6-hydroxy-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-5-yl]-(morpholino)methanone 1103738-19-7
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
200kg
Release date
2023-06-30
Hangzhou ICH Biofarm Co., Ltd
Product
(3aS,5R,6S,6aS)-[6-hydroxy-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-5-yl]-(morpholino)methanone 1103738-19-7
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
200kg
Release date
2023-06-30

1103738-19-7, ((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanoneRelated Search:

MK-4618 Pyrimidinone Acid Sodium Salt (6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one

  • D-xylo-Pentodialdo-5,2-furanose, 4,5-O-(1-Methylethylidene)-1-C-4-Morpholinyl-,(5S)-
  • ((3aS,5R,6S,6aS)-6-hydroxy-2,2-diMethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(Morpholino)Methanone
  • (3aS,5R,6S,6aS)-[6-hydroxy-2,2-dimethyltetrahydrofuro[3,2-d][1,3]dioxol-5-yl]-(morpholino)methanone
  • LX-4211 int
  • (5S)-4,5-O-(1-Methylethylidene)-1-C-4-morpholinyl-D-xylo-pentodialdo-5,2-furanose
  • LX-4211 inermediate
  • EOS-61383
  • SOTA-005
  • ((3aS,5S,6R,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone
  • LX-4211 intermediate
  • [(3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]-morpholin-4-ylmethanone
  • 2-dimethyltetrahydrofuro[2
  • 3]dioxol-5-yl)(morpholino)methanone
  • 6aS)-6-hydroxy-2
  • ((3aS,5R,6S,6aS)-6-hydroxy-2,2-diMethyltetrahydrofuro[2,3-d]...
  • D-xylo-Pentodialdo-5,2-furanose
  • (5S)-4,5-o-(1-Methylethylidene)-1-C-morpholin-4-yl-D-xylo-pentodialdo-5,2-furanose
  • (5S)-4,5-0-(1-Methylethylidene)-1-C-4- morpholinyl-D-xylo-pentodialdo-5,2-furanose
  • LX-4211 intermediate, 10 mM in DMSO
  • 1103738-19-7