(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one

Uses

Product Name: (6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one
CAS No.: 1190363-46-2
Chemical Name: (6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one
Synonyms: 5H-Cyclohepta[b]pyridin-5-one, 6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-, (6S,9R)-;EOS-60325;Ramazepam Impurity 8;BMS-846372 Impurity 1;Rimegepant Impurity 8;Rimegepant Impurity 14;(6S,9R)-6-(2,3-Difluoroph;5H-Cyclohepta[b]pyridin-5-one, 6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-;9-((triisopropylsilyl)oxy)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-5-one hydrochloride;ERT-BUTYL 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-3,6-DIHYDROPYRIDINE-1(2H)-CARBOXYLATE
CBNumber: CB02717474
Molecular Formula: C25H33F2NO2Si
Formula Weight: 445.62
MOL File: 1190363-46-2.mol

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(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one Property

Boiling point:: 477.5±45.0 °C(Predicted)
Density: 1.10±0.1 g/cm3(Predicted)
pka: 2.97±0.60(Predicted)
InChIKey: AIVVBBARCYSYDU-SIKLNZKXSA-N
SMILES: C12[C@H](O[Si](C(C)C)(C(C)C)C(C)C)CC[C@@H](C3=CC=CC(F)=C3F)C(=O)C1=CC=CN=2

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: ORS0014114
Product name: (6S,9R)-6-(2,3-DIFLUOROPHENYL)-9-((TRIISOPROPYLSILYL)OXY)-6,7,8,9-TETRAHYDRO-5H-CYCLOHEPTA[B]PYRIDIN-5-ONE
Purity: 95.00%
Packaging: 5MG
Price: $503.36
Updated: 2021/12/16

Chemenu

Product number: CM328793
Product name: 6-(2,3-difluorophenyl)-9-tri(propan-2-yl)silyloxy-6,7,8,9-tetrahydrocyclohepta[b]pyridin-5-one
Purity: 95+%
Packaging: 1000g
Price: $147200
Updated: 2021/12/16

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(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one Chemical Properties,Usage,Production

Uses

(6S,9R)-6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-9-[[triisopropylsilyl]oxy]-5H-cycloheptatrien[B]pyridin-5-one is a pharmaceutical chemical intermediate that can be used in the production of the drug molecule Remegapan.

Chemical Properties

(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[triisopropylsilyl]oxy]-5H-cycloheptatrieno[B]pyridin-5-one is a cycloheptanone-pyridinium organic compound with a reactive hydroxyl reactive group protected by a silyl unit in its structure, which can be hydrolyzed to remove the silyl protecting group under acidic conditions. In addition, its structure contains a carbonyl α-carbon atom chiral center, which is sensitive to alkalis and is prone to undergo enolic reciprocal isomerism under the action of bases leading to the disappearance of its chirality.

(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one Preparation Products And Raw materials

Raw materials

Preparation Products

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(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one Suppliers

China 137 India 2 Global 139

ChengDu TongChuangYuan Pharmaceutical Co.Ltd

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Jiangsu Vcare PharmaTech Co., Ltd.

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Syncozymes (Shanghai) Co.,Ltd.

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Suzhou Sino Rare Chemical Co., Ltd.

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Taizhou Tongxin Bio-Tech Co., Ltd

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Chengdu Climb Pharmaceutical Technology Co., Ltd.

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Shanghai Pansopharm Technology Co., Ltd.

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Taizhou Ruixin Chemical Co., Ltd.

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Cangzhou Enke Pharma-tech Co., Ltd.

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ChengDu TongChuangYuan Pharmaceutical Co.Ltd

Tel: 028-83379370 13880556291
Fax: 028-87747383
Email: tcy@tcypharm.com
Country: China
ProdList: 7218
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View Lastest Price from (6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: (6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one 1190363-46-2
Price: US $2.00-5.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-13

Hangzhou ICH Biofarm Co., Ltd

Product: 5H-?Cyclohepta[b]?pyridin-?5-?one, 6-?(2,?3-?difluorophenyl)?-?6,?7,?8,?9-?tetrahydro-?9-?[[tris(1-?methylethyl)?silyl]?oxy]?-?, (6S,?9R)?- 1190363-46-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100KG
Release date: 2023-06-28

1190363-46-2, (6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-oneRelated Search:

(R)-9-((triisopropylsilyl)oxy)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-5-onehydrochloride 2-Chloro-4-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)pyrimidine 1-(1-(1H-imidazole-1-carbonyl)piperidin-4-yl)-1H-imidazo[4,5-b]pyridin-2(3H)-one MK-4618 Pyrimidinone Acid Sodium Salt ((3AS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)(morpholino)methanone

(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one

ERT-BUTYL 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-3,6-DIHYDROPYRIDINE-1(2H)-CARBOXYLATE

(6S,9R)-6-(2,3-difluorophenyl)-9-(triisopropylsilyloxy)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-5-one

EOS-60325

(6S,9R)-6-(2,3-difluorophenyl)-9-tri(propan-2-yl)silyloxy-6,7,8,9-tetrahydrocyclohepta[b]pyridin-5-one

5H-Cyclohepta[b]pyridin-5-one, 6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-

BMS-846372 Impurity 1

5H-Cyclohepta[b]pyridin-5-one, 6-(2,3-difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-, (6S,9R)-

(6S,9R)-6-(2,3-Difluoroph

Rimegepant Impurity 8

(6S,9R)-6- (2,3-Difuorophenyl)-6.7,8.9-tetrahydro-9 [[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin 5-0n?

(6R,9S)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro- 9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-one

9-((triisopropylsilyl)oxy)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-5-one hydrochloride

(6S,9R)-6-(2,3-difluorophenyl)-9-{[tris(propan-2-yl)silyl]oxy}-5H,6H,7H,8H,9H-cyclohepta[b]pyridin-5-one

(6S, 9R) -6- (2,3-fluorophenyl) -6,7,8,9-tetrahydro-9- [[[triisopropylsilyl] oxy] -5H-cyclohepteno [B] pyridin-5-one

Rimegepant Impurity 14

Ramazepam Impurity 8

(6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[triisopropylsilyl]oxy]-5H-cycloheptatrien[B]pyridin-5-one

1190363-46-2

1373116-08-6

C25H33F2NO2Si

1190363-46-2