OG-L002

ChemicalBook > CAS DataBase List > OG-L002

Product Name: OG-L002
CAS No.: 1357302-64-7
Chemical Name: OG-L002
Synonyms: CS-830;OG-L002;OG-L002 USP/EP/BP;OGL002;OG L002;OGL-002;4'-((1R,2S)-2-Aminocyclopropyl)biphenyl-3-ol;4'-((1R,2S)-2-Aminocyclopropyl)-[1,1'-biphenyl]-3-ol;4'-((1R,2S)-2-Aminocyclopropyl)-[1,1'-biphenyl]-3-ol;[1,1'-Biphenyl]-3-ol, 4'-[(1R,2S)-2-aminocyclopropyl]-;[1,1'-Biphenyl]-3-ol, 4'-[(1R,2S)-2-aminocyclopropyl]-4'-((1R,2S)-2-Aminocyclopropyl)biphenyl-3-o;OG-L002 4'-((1S,2R)-2-aminocyclopropyl)-[1,1'-biphenyl]-3-ol 3-[4-[(1R,2S)-2-aminocyclopropyl]phenyl]phenol
CBNumber: CB12677399
Molecular Formula: C15H15NO
Formula Weight: 225.29
MOL File: 1357302-64-7.mol

Less

OG-L002 Property

Boiling point:: 416.7±45.0 °C(Predicted)
Density: 1.193±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: insoluble in H2O; ≥22.5 mg/mL in DMSO; ≥6.82 mg/mL in EtOH
form: solid
pka: 9.78±0.10(Predicted)

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 17471
Product name: OG-L002
Purity: ≥98%
Packaging: 1mg
Price: $36
Updated: 2024/03/01

Cayman Chemical

Product number: 17471
Product name: OG-L002
Purity: ≥98%
Packaging: 5mg
Price: $155
Updated: 2024/03/01

Cayman Chemical

Product number: 17471
Product name: OG-L002
Purity: ≥98%
Packaging: 10mg
Price: $274
Updated: 2024/03/01

Cayman Chemical

Product number: 17471
Product name: OG-L002
Purity: ≥98%
Packaging: 25mg
Price: $553
Updated: 2024/03/01

Tocris

Product number: 6244
Product name: OG-L002
Purity: ≥98%(HPLC)
Packaging: 25
Price: $450
Updated: 2021/12/16

Less

OG-L002 Chemical Properties,Usage,Production

Description

Lysine-specific demethylase 1 (LSD1) is a protein lysine demethylase that specifically demethylates histone H3 lysine 4 (H3K4) and H3K9, resulting in transcriptional repression. Host LSD1 is also recruited by certain viruses to limit H3K9 methylation, which can repress viral genes necessary for infection. Lysine-specific demethylase 1 (LSD1) is a protein lysine demethylase that specifically demethylates histone H3 lysine 4 (H3K4) and H3K9, resulting in transcriptional repression. Host LSD1 is also recruited by certain viruses to limit H3K9 methylation, which can repress viral genes necessary for infection. OG-L002 is a potent inhibitor of LSD1 (IC₅₀ = 0.02 μM) that less effectively inhibits the monoamine oxidases A (MAO-A) and MAO-B (IC₅₀s = 1.38 and 0.72 μM). It blocks the expression of immediate early (IE) genes of herpes simplex virus (HSV) in HeLa cells but not that of cellular control genes. OG-L002 also reduces the expression of human cytomegalovirus IE genes and adenovirus E1A gene in mammalian cells. It is effective in vivo, repressing HSV primary infection in mice and blocking HSV reactivation from latency in a mouse ganglion explant model.

Uses

OG-L002 is a novel, potent, and selective LSD1/KDM1A inhibitor that epigenetically blocks the herpes simplex lytic replication and reactivation from latency.

target

LSD1

storage

Store at -20°C

OG-L002 Preparation Products And Raw materials

Raw materials

Preparation Products

Less

OG-L002 Suppliers

China 86 India 2 United Kingdom 1 United States 10 Global 99

Jinan Trio PharmaTech Co., Ltd.

Tel: +86 (531) 88811783
Fax: +86 (531) 55696010 QQ 1762738062
Email: sales@trio-pharmatech.com (International market)
Country: China
ProdList: 1856
Advantage: 62

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4659
Advantage: 58

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7854
Advantage: 58

Hygeia (Chengdu) pharmaceutical technique Co., Ltd

Tel: 028-84502008 13568869383
Fax: 028-66476329
Email: sales@hygeiapharm.com
Country: China
ProdList: 294
Advantage: 55

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2989
Advantage: 60

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4153
Advantage: 55

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131981
Advantage: 58

Medi-tech Bioscientific Co., Ltd.

Tel: 0519-83246372 13585352506
Fax: 0519-83246372
Country: China
ProdList: 1844
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28821
Advantage: 58

Angel Pharmatech, Ltd.

Tel: 17317130613
Fax: QQ3358272972
Email: 3358272972@qq.com
Country: China
ProdList: 3242
Advantage: 58

Guangzhou Tomums Life Science Co., Ltd.

Tel: 020-31155029 18902330969
Fax: 020-31155029
Email: sales@tomums.cn
Country: China
ProdList: 4698
Advantage: 58

Zhejiang J&C Biological Technology Co.,Limited

Tel: +1-2135480471 +1-2135480471
Email: sales@sarms4muscle.com
Country: China
ProdList: 10523
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 28506
Advantage: 58

HANGZHOU CLAP TECHNOLOGY CO.,LTD

Tel: 86-571-88216897,88216896 13588875226
Fax: 86-571-88216895
Email: sales@hzclap.com
Country: CHINA
ProdList: 6313
Advantage: 58

DC Chemicals

Tel: 021-58447131 13564518121
Email: sales@dcchemicals.com
Country: China
ProdList: 9414
Advantage: 58

Absin Bioscience Inc.

Tel: 021-38015121 15000105423
Email: chenjw@absin.cn
Country: China
ProdList: 24734
Advantage: 58

Shanghai hongqu biomedical technology co. LTD

Tel: 88888888888
Email: hongquchem@qq.com
Country: China
ProdList: 5132
Advantage: 58

Taizhou Nanfeng Pharmaceutical Research Institute

Tel: 12345678910
Fax: nanfengdrug@163
Email: nanfengdrug@163.com
Country: China
ProdList: 15323
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44894
Advantage: 58

Wuhan Yanzhe Technology Co., Ltd

Tel: 15527250409
Fax: QQ：2692360204
Email: wenhaotian12@163.com
Country: China
ProdList: 4576
Advantage: 58

Wuhan Topule

Tel: +86-02787215551 +86-19945035818
Fax: 027-87215551
Email: 2936752263@qq.com
Country: China
ProdList: 7955
Advantage: 58

Nantong Feiyu Biological Technology CO.,LTD

Tel: 0513-68819626; 13813788405
Fax: 0513-68669626
Email: feiyubio2@163.com
Country: China
ProdList: 4821
Advantage: 58

Hubei Kele Fine Chemical Co., Ltd

Tel: 027-59101668 19945030958
Fax: 027-59101668
Email: 2881924765@qq.com
Country: China
ProdList: 7977
Advantage: 58

Wuhan Augda Biotechnology Co., Ltd

Tel: 15071299552
Fax: QQ:262933239
Email: 262933239@qq.com
Country: China
ProdList: 6637
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 15221909166
Email: product02@bidepharm.com
Country: China
ProdList: 61720
Advantage: 58

Kaifeng Mingren Pharmaceutical Co.,LTD

Tel: 0371-65741762
Fax: QQ：2860768577
Email: sales@hasunny.com
Country: China
ProdList: 2380
Advantage: 58

InvivoChem

Tel: 13549236410
Email: sales@invivochem.cn
Country: China
ProdList: 6712
Advantage: 58

Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.

Tel: +86-027-59232304 15387063101
Email: 2881924050@qq.com
Country: China
ProdList: 9892
Advantage: 58

Xianning Shen Lan Biomedical Research and Development Co., Ltd.

Tel: 18171815831
Email: 1341138380@qq.com
Country: China
ProdList: 2780
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 8740
Advantage: 58

Shanghai?Medlife?Pharm-Tech?Co.,?Ltd

Tel: 021-59167510 18117107507
Email: vip@med-life.cn
Country: China
ProdList: 5019
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-85560043 15850508050
Fax: 025-85563444
Email: cindy.huang@synzest.com
Country: China
ProdList: 12007
Advantage: 58

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Tel: +86-18521732826
Email: market@aladdin-e.com
Country: China
ProdList: 48467
Advantage: 58

Shanghai jerryxing Biomedical Technology Co., Ltd

Tel: 17721492509
Email: 643638326@qq.com
Country: China
ProdList: 5347
Advantage: 58

Wuhan Topule Biopharmaceutical Co., Ltd

Tel: +8618327326525
Email: masar@topule.com
Country: China
ProdList: 8474
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6846
Advantage: 58

Beijing Dongge Boye Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 1861586486@qq.com
Country: CHINA
ProdList: 6652
Advantage: 58

Shanghai Boyi Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: 15800446246@163.com
Country: CHINA
ProdList: 5417
Advantage: 58

Wuhan Boot Biotechnology Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6829
Advantage: 58

Beijing Chief-East Tech Co.,Ltd (Qwbio)

Tel: --
Fax: --
Email: info@qwbio.com
Country: China
ProdList: 6912
Advantage: 50

Shanghai Yijie Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: SHYIJIEBIO@126.COM
Country: CHINA
ProdList: 3510
Advantage: 58

Xiamen Huijia Biological Technology Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6979
Advantage: 58

Boao Pike

Tel: --
Fax: --
Email: lyn@biopike.com.cn
Country: CHINA
ProdList: 6629
Advantage: 58

Qingdao Jieshikang Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: jskangchina@163.com
Country: CHINA
ProdList: 4012
Advantage: 58

Shanghai Benrui Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: john.st@163.com
Country: CHINA
ProdList: 1472
Advantage: 58

Nanjing Sai Ruirui Biotechnology Co., Ltd.

Tel: --
Fax: --
Email: sales@shrbio.com
Country: CHINA
ProdList: 6873
Advantage: 58

Beijing Taize Ruida Technology Co., Ltd.

Tel: --
Fax: --
Email: taizeorder@163.com
Country: CHINA
ProdList: 6536
Advantage: 58

Beijing Lebo Biotechnology Co., Ltd.

Tel: --
Fax: --
Country: CHINA
ProdList: 6057
Advantage: 58

1357302-64-7, OG-L002Related Search:

BIX 01294 Tazemetostat (EPZ-6438) GSK J4 HCl 6-CHLORO-2,3,4,9-TETRAHYDRO-1H-CARBAZOLE-1-CARBOXAMIDE (2R,3R,4S,5R)-2-(6-aMino-9H-purin-9-yl)-5-((((1r,3S)-3-(2-(5-(tert-butyl)-1H-benzo[d]iMidazol-2-yl)ethyl)cyclobutyl)(isopropyl)aMino)Methyl)tetrahydrofuran-3,4-diol MM-102

OG-L002

[1,1'-Biphenyl]-3-ol, 4'-[(1R,2S)-2-aminocyclopropyl]-4'-((1R,2S)-2-Aminocyclopropyl)biphenyl-3-o

OG-L002 [1,1'-Biphenyl]-3-ol, 4'-[(1R,2S)-2-aminocyclopropyl]-

OG-L002 4'-((1S,2R)-2-aminocyclopropyl)-[1,1'-biphenyl]-3-ol 3-[4-[(1R,2S)-2-aminocyclopropyl]phenyl]phenol

OGL002;OG L002;OGL-002

CS-830

4'-((1R,2S)-2-Aminocyclopropyl)biphenyl-3-ol

4'-((1R,2S)-2-Aminocyclopropyl)-[1,1'-biphenyl]-3-ol

[1,1'-Biphenyl]-3-ol, 4'-[(1R,2S)-2-aminocyclopropyl]-

OG-L002 USP/EP/BP

4'-((1R,2S)-2-Aminocyclopropyl)-[1,1'-biphenyl]-3-ol

1357302-64-7

Inhibitors