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alisporivir

Product Name
alisporivir
CAS No.
254435-95-5
Chemical Name
alisporivir
Synonyms
DEB-025;Debio-025;alisporivir;Alisporivir (Debio-025);alisporivir /DB025/DB-025;Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-D-alanyl-N-ethyl-L-valyl-L-valyl-N-methyl-L-leucyl]
CBNumber
CB12677410
Molecular Formula
C63H113N11O12
Formula Weight
1216.66
MOL File
254435-95-5.mol
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alisporivir Property

Boiling point:
1294.2±65.0 °C(Predicted)
Density 
1.011±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : ≥ 100 mg/mL (82.19 mM)
pka
13.32±0.70(Predicted)
form 
Solid
color 
White to off-white
Sequence
Cyclo({N-Me-Bmt(E)}-{Abu}-{d-N-Me-Ala}-{N-Et-Val)-Val-{N-Me-Leu}-Ala-{d-Ala}-{N-Me-Leu}-{N-Me-Leu}-{N-Me-Val})
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H361Suspected of damaging fertility or the unborn child

H372Causes damage to organs through prolonged or repeated exposure

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P281Use personal protective equipment as required.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

P314Get medical advice/attention if you feel unwell.

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML3856
Product name
Alisporivir
Purity
≥95% (HPLC)
Packaging
1mg
Price
$94.05
Updated
2025/07/31
Sigma-Aldrich
Product number
SML3856
Product name
Alisporivir
Purity
≥95% (HPLC)
Packaging
5mg
Price
$399
Updated
2025/07/31
ChemScene
Product number
CS-7501
Product name
Alisporivir
Purity
98.15%
Packaging
1mg
Price
$700
Updated
2021/12/16
ChemScene
Product number
CS-7501
Product name
Alisporivir
Purity
98.15%
Packaging
5mg
Price
$2100
Updated
2021/12/16
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alisporivir Chemical Properties,Usage,Production

Uses

Trofinetide is a synthetic analogue of the endogenous N-terminus tripeptide, Glycine-Proline-Glutamate (GPE), that has shown to be neuroprotective in animal models of brain injury.

Definition

ChEBI: Alisporivir is a homodetic cyclic peptide. It has a role as an anticoronaviral agent.

Biological Activity

Alisporivir is a Cyclophilin A inhibitor with potent anti-hepatitis C virus (HCV) activity. Alisporivir has also been investigated for Duchenne muscular dystrophy.

in vivo

Combination treatment with Alisporivir and ICN-1229 does not protect against SARS-CoV infection in a mouse model[3].

alisporivir Preparation Products And Raw materials

Raw materials

Preparation Products

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alisporivir Suppliers

ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3506
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9126
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Heze Development Zone chuangli Chemical Co., Ltd.
Tel
0530-+86-530-529 6766,+86-15666160102 15666160102
Fax
0530-529 6766
Email
info@chuangli-chem.com
Country
China
ProdList
836
Advantage
55
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
Guangzhou Belka Biological Technology Co., Ltd.
Tel
+86-18665676617
Fax
18665676617
Country
China
ProdList
957
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
LEADMEDPHARM CO.,LTD
Tel
13674959855 13674959855
Email
sales@synthontech.com
Country
China
ProdList
3035
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Wuhan Topule
Tel
+86-02787215551 +86-19945035818
Fax
027-87215551
Email
2936752263@qq.com
Country
China
ProdList
7986
Advantage
58
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View Lastest Price from alisporivir manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
Alisporivir 254435-95-5
Price
US $2.00-5.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-25

254435-95-5, alisporivirRelated Search:


  • alisporivir
  • alisporivir /DB025/DB-025
  • Alisporivir (Debio-025)
  • DEB-025
  • Debio-025
  • Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-D-alanyl-N-ethyl-L-valyl-L-valyl-N-methyl-L-leucyl]
  • 254435-95-5