ChemicalBook > CAS DataBase List > PLpro inhibitor
PLpro inhibitor
- Product Name
- PLpro inhibitor
- CAS No.
- 1093070-14-4
- Chemical Name
- PLpro inhibitor
- Synonyms
- HY-17542;PLpro inhibitor;Plpro-IN-6(PLpro inhibitor);5-acetamido-2-methyl-n-(2-naphthalen-1-ylethyl)benzamide;5-acetamido-2-methyl-N-[2-(1-naphthalenyl)ethyl]benzamide;5-(acetylamino)-2-methyl-N-[(1R)-1-(1-naphthalenyl)ethyl]-;5-acetylamino-2-methyl-N-[(R)-1-(1-naphthyl)ethyl]benzamide;Inhibitor,SARS-CoV,SARS coronavirus,PLpro inhibitor,inhibit;5-Acetylamino-2-methyl-N-(1R-naphthalen-1-yl-ethyl)benzamide;(R)-5-Acetamido-2-methyl-N-(1-(naphthalen-1-yl)ethyl)benzamide
- CBNumber
- CB12685934
- Molecular Formula
- C22H22N2O2
- Formula Weight
- 346.42
- MOL File
- 1093070-14-4.mol
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PLpro inhibitor Property
- Boiling point:
- 584.7±50.0 °C(Predicted)
- Density
- 1.189±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml
- form
- Powder
- pka
- 14.13±0.46(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-2273
- Product name
- PLproinhibitor
- Purity
- 99.79%
- Packaging
- 5mg
- Price
- $420
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-2273
- Product name
- PLproinhibitor
- Purity
- 99.79%
- Packaging
- 10mg
- Price
- $600
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CCH0000210
- Product name
- 5-ACETYLAMINO-2-METHYL-N-(1R-NAPHTHALEN-1-YL-ETHYL)-BENZAMIDE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $866.25
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-2273
- Product name
- PLproinhibitor
- Purity
- 99.79%
- Packaging
- 50mg
- Price
- $1800
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-2273
- Product name
- PLproinhibitor
- Purity
- 99.79%
- Packaging
- 100mg
- Price
- $2520
- Updated
- 2021/12/16
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PLpro inhibitor Chemical Properties,Usage,Production
Definition
ChEBI: KOM70144 is a benzamide that is GRL-0617 in which one of the hydrogen's of the primary amino group is replaced by an acetyl group. It an inhibitor of SARS-CoV and SARS-CoV-2 papain-like protease (PLpro) with an IC50 of 2.6 muM and 5.0 muM, respectively. It also inhibits SARS-CoV and SARS-CoV-2 infection of Vero E6 cells in vitro (EC50 values are 13.1 and 21 muM, respectively). It has a role as a protease inhibitor and an anticoronaviral agent. It is a member of naphthalenes, a member of benzamides, a secondary carboxamide and a member of acetamides. It is functionally related to a GRL-0617.
storage
Store at -20°C
PLpro inhibitor Preparation Products And Raw materials
Raw materials
Preparation Products
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