ChemicalBook > CAS DataBase List > 21-Chloro-9-fluoro-11β,17-dihydroxy-16β-Methylpregn-4-ene-3,20-dione 17-Propionate

21-Chloro-9-fluoro-11β,17-dihydroxy-16β-Methylpregn-4-ene-3,20-dione 17-Propionate

Product Name
21-Chloro-9-fluoro-11β,17-dihydroxy-16β-Methylpregn-4-ene-3,20-dione 17-Propionate
CAS No.
25120-99-4
Chemical Name
21-Chloro-9-fluoro-11β,17-dihydroxy-16β-Methylpregn-4-ene-3,20-dione 17-Propionate
Synonyms
Clobetasol Impurity D;Clobetasol EP Impurity D;Clobetasol Propionate EP Impurity D;Clobetasol Propionate Impurity 4(Clobetasol Propionate EP Impurity D);21-Chloro-9-fluoro-11b-hydroxy-16b-methyl-3,20-dioxopregn-4-en-17-yl propanoate;21-Chloro-9-fluoro-11b,17-dihydroxy-16b-methylpregn-4-ene-3,20-dione 17-Propionate;Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (11β,16β)-;Clobetasol Propionate EP Impurity D/(11beta,16beta)-21-Chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)pregn-4-ene-3,20-dione;(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-Chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl propionate (Clobetasol Propionate Impurity)
CBNumber
CB12695023
Molecular Formula
C25H34ClFO5
Formula Weight
468.99
MOL File
25120-99-4.mol
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21-Chloro-9-fluoro-11β,17-dihydroxy-16β-Methylpregn-4-ene-3,20-dione 17-Propionate Property

Melting point:
>188°C (dec.)
Boiling point:
568.5±50.0 °C(Predicted)
Density 
1.26±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Dioxane (Slightly), Methanol (Slightly)
pka
12.97±0.70(Predicted)
form 
Solid
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
C366305
Product name
21-Chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregn-4-ene-3,20-dione17-Propionate
Packaging
250mg
Price
$1620
Updated
2021/12/16
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21-Chloro-9-fluoro-11β,17-dihydroxy-16β-Methylpregn-4-ene-3,20-dione 17-Propionate Chemical Properties,Usage,Production

Uses

21-Chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregn-4-ene-3,20-dione 17-Propionate (Clobetasol Propionate EP Impurity D) is an impurity of Clobetasol 17-Propionate (C583500), an topical corticosteroid with anti-inflammatory properties.

Uses

21-Chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregn-4-ene-3,20-dione 17-Propionate is an impurity of Clobetasol 17-Propionate (C583500), an topical corticosteroid with anti-inflammatory properties.

21-Chloro-9-fluoro-11β,17-dihydroxy-16β-Methylpregn-4-ene-3,20-dione 17-Propionate Preparation Products And Raw materials

Raw materials

Preparation Products

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21-Chloro-9-fluoro-11β,17-dihydroxy-16β-Methylpregn-4-ene-3,20-dione 17-Propionate Suppliers

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25120-99-4, 21-Chloro-9-fluoro-11β,17-dihydroxy-16β-Methylpregn-4-ene-3,20-dione 17-PropionateRelated Search:


  • Clobetasol Propionate EP Impurity D
  • Clobetasol Propionate Impurity 4(Clobetasol Propionate EP Impurity D)
  • Clobetasol Impurity D
  • Clobetasol Propionate EP Impurity D/(11beta,16beta)-21-Chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)pregn-4-ene-3,20-dione
  • Pregn-4-ene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (11β,16β)-
  • 21-Chloro-9-fluoro-11b-hydroxy-16b-methyl-3,20-dioxopregn-4-en-17-yl propanoate
  • Clobetasol EP Impurity D
  • (8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-Chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl propionate (Clobetasol Propionate Impurity)
  • 21-Chloro-9-fluoro-11b,17-dihydroxy-16b-methylpregn-4-ene-3,20-dione 17-Propionate
  • 25120-99-4
  • C25H34ClFO5
  • Pharmaceuticals, Intermediates & Fine Chemicals, Steroids