Clobetasol
- Product Name
- Clobetasol
- CAS No.
- 25122-41-2
- Chemical Name
- Clobetasol
- Synonyms
- CLOBETASOLE PROPIONATE;CLOBETASOL-17-PROPIONATE;Clobetasol;ClobetasolBase;Clobetasol USP/EP/BP;Clobetasol Impurity G;CLOBESTASOL PROPIONATE;Betamethasone Impurity B;BETAMETHASONE EP MPURITY B;Clobetasol impurity G (PhEur)
- CBNumber
- CB8715108
- Molecular Formula
- C22H28ClFO4
- Formula Weight
- 410.91
- MOL File
- 25122-41-2.mol
Clobetasol Property
- Melting point:
- 220-222°C
- Boiling point:
- 555.1±50.0 °C(Predicted)
- Density
- 1.32±0.1 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 12.03±0.70(Predicted)
- color
- White to Light Brown
Safety
- Hazard Codes
- T
- Risk Statements
- 61-48/20/21-53-62
- Safety Statements
- 53-36/37-45
- Hazardous Substances Data
- 25122-41-2(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H373May cause damage to organs through prolonged or repeated exposure
H413May cause long lasting harmful effects to aquatic life
- Precautionary statements
-
P201Obtain special instructions before use.
P308+P313IF exposed or concerned: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- C583490
- Product name
- Clobetasol
- Packaging
- 100mg
- Price
- $1210
- Updated
- 2021/12/16
- Product number
- API0024630
- Product name
- CLOBETASOL
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $1758.49
- Updated
- 2021/12/16
- Product number
- 68820
- Product name
- Clobetasol
- Packaging
- 100mg
- Price
- $2000
- Updated
- 2021/12/16
- Product number
- 68820
- Product name
- Clobetasol
- Packaging
- 10mg
- Price
- $625
- Updated
- 2021/12/16
- Product number
- API0024630
- Product name
- CLOBETASOL
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $697.34
- Updated
- 2021/12/16
Clobetasol Chemical Properties,Usage,Production
Chemical Properties
White to Off-White Solid
Originator
Dermovate,Glaxo,UK,1973
Uses
Clobetasol (Clobetasol Propionate EP Impurity G) is a topical corticosteroid. Glucocorticoid; anti-inflammatory.
Uses
Atorvastatin Intermediate
Definition
ChEBI: A 3-oxo-Delta1,Delta4-steroid that is 16beta-methylpregna-1,4-diene-3,20-dione bearing hydroxy groups at the 11beta and 17alpha posit ons, fluorine at position 9, and a chlorine substituent at position 21. It is used as its 17alpha-propionate ester to treat various skin disorders, including exzema and psoriasis.
Manufacturing Process
A solution of betamethasone 21-methanesulfonate (4 g) in dimethylformamide
(25 ml) was treated with lithium chloride (4 g) and the mixture heated on the
steam bath for 30 minutes. Dilution with water gave the crude product which
was recrystallized to afford the title compound, MP 226°C.
Clobetasol is usually converted to the propionate as the useful form by
reaction with propionic anhydride.
brand name
Clobex (Galderma); Clobex (Galderma); Embeline (Healthpoint); Olux (Connetics); Temovate (Altana).
Therapeutic Function
Corticosteroid, Antiinflammatory
Clobetasol Preparation Products And Raw materials
Raw materials
Preparation Products
Clobetasol Suppliers
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View Lastest Price from Clobetasol manufacturers
- Product
- Clobetasol 25122-41-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-25
- Product
- Betamethasone EP Impurity B 25122-41-2
- Price
- US $0.00/mg
- Min. Order
- 10mg
- Purity
- 0.98
- Supply Ability
- 10g
- Release date
- 2024-04-01
- Product
- Betamethasone EP Impurity B 25122-41-2
- Price
- US $0.00/mg
- Min. Order
- 10mg
- Purity
- 0.98
- Supply Ability
- 10g
- Release date
- 2024-04-01