Clobetasol

Product Name: Clobetasol
CAS No.: 25122-41-2
Chemical Name: Clobetasol
Synonyms: CLOBETASOLE PROPIONATE;CLOBETASOL-17-PROPIONATE;Clobetasol;ClobetasolBase;Clobetasol USP/EP/BP;Clobetasol Impurity G;CLOBESTASOL PROPIONATE;Betamethasone Impurity B;BETAMETHASONE EP MPURITY B;Clobetasol impurity G (PhEur)
CBNumber: CB8715108
Molecular Formula: C22H28ClFO4
Formula Weight: 410.91
MOL File: 25122-41-2.mol

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Clobetasol Property

Melting point:: 220-222°C
Boiling point:: 555.1±50.0 °C(Predicted)
Density: 1.32±0.1 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 12.03±0.70(Predicted)
color: White to Light Brown

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Safety

Hazard Codes: T
Risk Statements: 61-48/20/21-53-62
Safety Statements: 53-36/37-45
Hazardous Substances Data: 25122-41-2(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P201Obtain special instructions before use.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC

Product number: C583490
Product name: Clobetasol
Packaging: 100mg
Price: $1210
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0024630
Product name: CLOBETASOL
Purity: 95.00%
Packaging: 100MG
Price: $1758.49
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 68820
Product name: Clobetasol
Packaging: 100mg
Price: $2000
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 68820
Product name: Clobetasol
Packaging: 10mg
Price: $625
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0024630
Product name: CLOBETASOL
Purity: 95.00%
Packaging: 10MG
Price: $697.34
Updated: 2021/12/16

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Clobetasol Chemical Properties,Usage,Production

Chemical Properties

White to Off-White Solid

Originator

Dermovate,Glaxo,UK,1973

Uses

Clobetasol (Clobetasol Propionate EP Impurity G) is a topical corticosteroid. Glucocorticoid; anti-inflammatory.

Uses

Atorvastatin Intermediate

Definition

ChEBI: A 3-oxo-Delta1,Delta4-steroid that is 16beta-methylpregna-1,4-diene-3,20-dione bearing hydroxy groups at the 11beta and 17alpha posit ons, fluorine at position 9, and a chlorine substituent at position 21. It is used as its 17alpha-propionate ester to treat various skin disorders, including exzema and psoriasis.

Manufacturing Process

A solution of betamethasone 21-methanesulfonate (4 g) in dimethylformamide (25 ml) was treated with lithium chloride (4 g) and the mixture heated on the steam bath for 30 minutes. Dilution with water gave the crude product which was recrystallized to afford the title compound, MP 226°C.
Clobetasol is usually converted to the propionate as the useful form by reaction with propionic anhydride.

brand name

Clobex (Galderma); Clobex (Galderma); Embeline (Healthpoint); Olux (Connetics); Temovate (Altana).

Therapeutic Function

Corticosteroid, Antiinflammatory

Clobetasol Preparation Products And Raw materials

Raw materials

Preparation Products

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Clobetasol Suppliers

Canada 2 China 104 China Hong Kong 1 Europe 3 France 1 Germany 1 India 13 Israel 1 United Kingdom 2 United States 18 Global 146

Toronto Research Chemicals

Tel: --
Fax: --
Email: info@trc-canada.com
Country: Canada
ProdList: 6088
Advantage: 71

Dalton Chemical Laboratories, Inc.

Tel: --
Fax: --
Email: chemist@dalton.com
Country: Canada
ProdList: 966
Advantage: 78

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View Lastest Price from Clobetasol manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD

Product: Betamethasone EP Impurity B 25122-41-2
Price: US $0.00/mg
Min. Order: 10mg
Purity: 0.98
Supply Ability: 10g
Release date: 2024-04-01

ShenZhen H&D Pharmaceutical Technology Co., LTD

Product: Betamethasone EP Impurity B 25122-41-2
Price: US $0.00/mg
Min. Order: 10mg
Purity: 0.98
Supply Ability: 10g
Release date: 2024-04-01

XI'AN TIANGUANGYUAN BIOTECH CO., LTD.

Product: Clobetasol 25122-41-2
Price: US $1200.00/Kg/Bag
Min. Order: 1Kg/Bag
Purity: 99%
Supply Ability: 1000kg/month
Release date: 2021-08-24

25122-41-2, ClobetasolRelated Search:

Betamethasone-17-ketone Betamethasone EP Impurity D Betamethasone Impurity 35 11-Oxo-betaMethasone Dipropionate Mometasone furoate Trimethyl borate Dexamethasone 9β,11β-Epoxy-17,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17,21-dihydroxy-16beta-methylpregna-1,4,9(11)-triene-3,20-dione Ethanone, 2-chloro-1-cyclopentyl- (9CI) CLOBETASOL PROPIONATE RELATED COMPOUND A (50 MG) (9-ALPHA-FLUORO-11-BETA-HYDROXY-16-BETA-METHYL-3-OXO-ANDROSTA-1,4-DIENE-17(R)-SPIRO-2'-[4'-CHLORO-5'-ETHYLFURAN-3'(2'H)-ONE]) Halobetasol propionate Clobetasol propionate CLOBETASOL FOR PEAK IDENTIFICATION,CLOBETASOL FOR PEAK IDENTIFICATION CLOBETASOL IMPURITY J,CLOBETASOL IMPURITY J HALOBETASOL Clobetasol fluoro jade

ClobetasolBase

Clobetasol Propionate 25122-46-7 / Base

21-Chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione

CLOBETASOLE PROPIONATE

CLOBETASOL-17-PROPIONATE

CLOBESTASOL PROPIONATE

Clobetasol (Betamethasone Impurity B)

(11β,16β)-21-Chloro-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione

Clobetasol impurity G (PhEur)

Clobetasol Propionate Impurity 7(Clobetasol Propionate EP Impurity G)

17-(2-Chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8, 11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one

Clobetasol

Clobetasol (Betamethasone EP Impurity B)

Clobetasol Propionate EP Impurity G

Clobetasol Impurity G

Betamethasone Impurity 2（Betamethasone EP Impurity B）

Betamethasone impurity 1/Betamethasone EP Impurity B/Clobetasol/21-Chloro-9-fluoro-11?,17-dihydroxy-16?-methylpregna-1,4-diene-3,20-dione

Clobetasol Propionate EP IMP G

21-Chloro-9-fluoro-11beta,17-dihydr

Pregna-1,4-diene-3,20-dione, 21-chloro-9-fluoro-11,17-dihydroxy-16-methyl-, (11β,16β)-

Clobetasol Propionate EP Impurity G/Betamethasone EP Impurity B

Clobetasol USP/EP/BP

Clobetasol (1.0 mg/mL in Methanol)

Betamethasone Impurity B

Clobetasol Propionate Impurity-G (EP)/ Betamethasone Impurity B (EP)

Betamethasone Impurity B (EP)/ Clobetasol Propionate Impurity-G (EP)

Clobetasol D5Q: What is Clobetasol D5 Q: What is the CAS Number of Clobetasol D5 Q: What is the storage condition of Clobetasol D5 Q: What are the applications of Clobetasol D5

21-Chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione

(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

Clobetasol Propionate Impurity G

Betamethasone EP Impurity B（Clobetasol Propionate EP Impurity G）

Clobetasol (Betamethasone EP Impurity B, Clobetasol Propionate EP Impurity G)

1, 4-PREGNADIEN-21-CHLORO-9α-FLUORO-16β-METHYL-11β, 17α-DIOL-3, 20-DIONE

21-chloro-9-uoro-11β,17-dihydroxy-16β-methylpregna- 1,4-diene-3,20-dione

BETAMETHASONE EP MPURITY B

25122-41-2

C22H28ClFO4

CI - CL

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Steroids