ChemicalBook > CAS DataBase List > Clobetasol
Clobetasol
- Product Name
- Clobetasol
- CAS No.
- 25122-41-2
- Chemical Name
- Clobetasol
- Synonyms
- CLOBETASOLE PROPIONATE;CLOBETASOL-17-PROPIONATE;Clobetasol;ClobetasolBase;Clobetasol USP/EP/BP;Clobetasol Impurity G;CLOBESTASOL PROPIONATE;Betamethasone Impurity B;Clobetasol impurity G (PhEur);Clobetasol Propionate EP IMP G
- CBNumber
- CB8715108
- Molecular Formula
- C22H28ClFO4
- Formula Weight
- 410.91
- MOL File
- 25122-41-2.mol
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Clobetasol Property
- Melting point:
- 220-222°C
- Boiling point:
- 555.1±50.0 °C(Predicted)
- Density
- 1.32±0.1 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 12.03±0.70(Predicted)
- color
- White to Light Brown
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Safety
- Hazard Codes
- T
- Risk Statements
- 61-48/20/21-53-62
- Safety Statements
- 53-36/37-45
- Hazardous Substances Data
- 25122-41-2(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H373May cause damage to organs through prolonged or repeated exposure
H413May cause long lasting harmful effects to aquatic life
- Precautionary statements
-
P201Obtain special instructions before use.
P308+P313IF exposed or concerned: Get medical advice/attention.
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N-Bromosuccinimide Price
TRC
- Product number
- C583490
- Product name
- Clobetasol
- Packaging
- 100mg
- Price
- $1210
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0024630
- Product name
- CLOBETASOL
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $1758.49
- Updated
- 2021/12/16
Medical Isotopes, Inc.
- Product number
- 68820
- Product name
- Clobetasol
- Packaging
- 100mg
- Price
- $2000
- Updated
- 2021/12/16
Medical Isotopes, Inc.
- Product number
- 68820
- Product name
- Clobetasol
- Packaging
- 10mg
- Price
- $625
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0024630
- Product name
- CLOBETASOL
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $697.34
- Updated
- 2021/12/16
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Clobetasol Chemical Properties,Usage,Production
Chemical Properties
White to Off-White Solid
Originator
Dermovate,Glaxo,UK,1973
Uses
Clobetasol (Clobetasol Propionate EP Impurity G) is a topical corticosteroid. Glucocorticoid; anti-inflammatory.
Uses
Atorvastatin Intermediate
Definition
ChEBI: A 3-oxo-Delta1,Delta4-steroid that is 16beta-methylpregna-1,4-diene-3,20-dione bearing hydroxy groups at the 11beta and 17alpha posit ons, fluorine at position 9, and a chlorine substituent at position 21. It is used as its 17alpha-propionate ester to treat various skin disorders, including exzema and psoriasis.
Manufacturing Process
A solution of betamethasone 21-methanesulfonate (4 g) in dimethylformamide
(25 ml) was treated with lithium chloride (4 g) and the mixture heated on the
steam bath for 30 minutes. Dilution with water gave the crude product which
was recrystallized to afford the title compound, MP 226°C.
Clobetasol is usually converted to the propionate as the useful form by
reaction with propionic anhydride.
brand name
Clobex (Galderma); Clobex (Galderma); Embeline (Healthpoint); Olux (Connetics); Temovate (Altana).
Therapeutic Function
Corticosteroid, Antiinflammatory
Clobetasol Preparation Products And Raw materials
Raw materials
Preparation Products
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Clobetasol Suppliers
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View Lastest Price from Clobetasol manufacturers
ShenZhen H&D Pharmaceutical Technology Co., LTD
- Product
- Betamethasone EP Impurity B 25122-41-2
- Price
- US $0.00/mg
- Min. Order
- 10mg
- Purity
- 0.98
- Supply Ability
- 10g
- Release date
- 2024-04-01
ShenZhen H&D Pharmaceutical Technology Co., LTD
- Product
- Betamethasone EP Impurity B 25122-41-2
- Price
- US $0.00/mg
- Min. Order
- 10mg
- Purity
- 0.98
- Supply Ability
- 10g
- Release date
- 2024-04-01
Hebei Yanxi Chemical Co., Ltd.
- Product
- Clobetasol 25122-41-2
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2023-11-16
25122-41-2, ClobetasolRelated Search:
Betamethasone-17-ketone
Betamethasone EP Impurity D
Betamethasone Impurity 35
11-Oxo-betaMethasone Dipropionate
Mometasone furoate
Trimethyl borate
Dexamethasone
9β,11β-Epoxy-17,21-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione
17,21-dihydroxy-16beta-methylpregna-1,4,9(11)-triene-3,20-dione
Ethanone, 2-chloro-1-cyclopentyl- (9CI)
CLOBETASOL PROPIONATE RELATED COMPOUND A (50 MG) (9-ALPHA-FLUORO-11-BETA-HYDROXY-16-BETA-METHYL-3-OXO-ANDROSTA-1,4-DIENE-17(R)-SPIRO-2'-[4'-CHLORO-5'-ETHYLFURAN-3'(2'H)-ONE])
Halobetasol propionate
Clobetasol propionate
CLOBETASOL FOR PEAK IDENTIFICATION,CLOBETASOL FOR PEAK IDENTIFICATION
CLOBETASOL IMPURITY J,CLOBETASOL IMPURITY J
HALOBETASOL
Clobetasol
fluoro jade