PNU-159682

Product Name: PNU-159682
CAS No.: 202350-68-3
Chemical Name: PNU-159682
Synonyms: PNU-159682;PNU-159682 95%;PNU-159682 >95%; 5-hydroxy-6-tert.-butyl-1,1-pentamethylene-3,3-dimethyl-indane;inhibit,non-Hodgkin’s lymphoma,PNU159682,ADCs Toxin,PNU-159682,acute myeloid leukemia,ADC Payload,EDV nanocell,AML,Inhibitor,ADC Cytotoxin,PNU 159682,Topoisomerase,NMS249,NHL;(8S,10S)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-{[(2S,4R,6S,7S,9R,10S)-10-methoxy-6-methyl-5,8,11-trioxa-1-azatricyclo[7.4.0.02,?]tridecan-4-yl]oxy}-5,7,8,9,10,12-hexahydrotetracene-5,12-dione;(8S,10S)-6,8,11-Trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-(((1S,3R,4aS,9S,9aR,10aS)-9-methoxy-1-methyloctahydro-1H-pyrano[4',3':4,5]oxazolo[2,3-c][1,4]oxazin-3-yl)oxy)-7,8,9,10-tetrahydrotetracene-5,12-dione;(8S,10S)-6,8,11-Trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-(((1S,3R,4aS,9S,9aR,10aS)-9-methoxy-1-methyloctahydro-1H-pyrano[4',3':4,5]oxazolo[2,3-c][1,4]oxazin-3-yl)oxy)-7,8,9,10-tetrahydrotetracene-5,12-dione;(8S,10S)-7,8,9,10-Tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[(1S,3R,4aS,9S,9aR,10aS)-octahydro-9-methoxy-1-methyl-1H-pyrano[4',3':4,5]oxazolo[2,3-c][1,4]oxazin-3-yl]oxy]-5,12-naphthacenedione;5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[(1S,3R,4aS,9S,9aR,10aS)-octahydro-9-methoxy-1-methyl-1H-pyrano[4',3':4,5]oxazolo[2,3-c][1,4]oxazin-3-yl]oxy]-, (8S,10S)-
CBNumber: CB12702958
Molecular Formula: C32H35NO13
Formula Weight: 641.62
MOL File: 202350-68-3.mol

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PNU-159682 Property

Boiling point:: 838.5±65.0 °C(Predicted)
Density: 1.58±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 7.34±0.60(Predicted)
form: Solid
color: Reddish Brown to red

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-3298
Product name: PNU-159682
Purity: 97.24%
Packaging: 5mg
Price: $750
Updated: 2021/12/16

ChemScene

Product number: CS-3298
Product name: PNU-159682
Purity: 97.24%
Packaging: 10mg
Price: $1000
Updated: 2021/12/16

ChemScene

Product number: CS-3298
Product name: PNU-159682
Purity: 97.24%
Packaging: 50mg
Price: $2400
Updated: 2021/12/16

Crysdot

Product number: CD31002752
Product name: PNU-159682
Purity: 98+%
Packaging: 50mg
Price: $3750
Updated: 2021/12/16

Crysdot

Product number: CD31002752
Product name: PNU-159682
Purity: 98+%
Packaging: 100mg
Price: $6150
Updated: 2021/12/16

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PNU-159682 Chemical Properties,Usage,Production

Characteristics

PNU-159682, a metabolite of the anthracycline neomycin metabolite, is a DNA topoisomerase I (TopoI) inhibitor with excellent cytotoxicity. It is a more potent and tolerable ADC cytotoxin than doxorubicin in ADC synthesis.

Uses

PNU-159682 can be used in EDV nanocell technology to overcome drug resistance.

PNU-159682 Preparation Products And Raw materials

Raw materials

Preparation Products

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PNU-159682 Suppliers

China 74 United States 8 Global 82

WuYan Pharmaceutical Technology (Shanghai) Co., Ltd.

Tel: 021-61001086 13671938079
Fax: 021-61114075
Email: sales@wuyanpharm.com
Country: China
ProdList: 105
Advantage: 55

Levena (Suzhou) Biopharma Co., Ltd.

Tel: 0512-81877925 051281877925
Email: info@levena.cn
Country: China
ProdList: 48
Advantage: 58

Shanghai ruichang pharmaceutical technology co., LTD

Tel: 18621054990
Email: maychemicals@sina.com
Country: China
ProdList: 673
Advantage: 58

Wuhan Topule

Tel: +86-02787215551 +86-19945035818
Fax: 027-87215551
Email: 2936752263@qq.com
Country: China
ProdList: 8084
Advantage: 58

Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.

Tel: +86-027-59232304 15387063101
Email: 2881924050@qq.com
Country: China
ProdList: 9959
Advantage: 58

Xianning Shen Lan Biomedical Research and Development Co., Ltd.

Tel: 18171815831
Email: 1341138380@qq.com
Country: China
ProdList: 3665
Advantage: 58

Wuhan Augda Biotechnology Co., Ltd

Tel: 15071299552
Fax: QQ:262933239
Email: 262933239@qq.com
Country: China
ProdList: 6887
Advantage: 58

EnliPharma Technology Co., Ltd

Tel: 0551-66399836 18955197623
Email: sales@enlipharma.com
Country: China
ProdList: 1874
Advantage: 55

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

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View Lastest Price from PNU-159682 manufacturers

Wuhan Topule Biopharmaceutical Co., Ltd

Product: PNU-159682 202350-68-3
Price: US $10.00/mg
Min. Order: 10mg
Purity: 95%+
Supply Ability: 500g
Release date: 2023-06-13

Career Henan Chemical Co

Product: PNU-159682 202350-68-3
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-02-13

202350-68-3, PNU-159682Related Search:

PNU-159682

PNU-159682 >95%

(8S,10S)-7,8,9,10-Tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[(1S,3R,4aS,9S,9aR,10aS)-octahydro-9-methoxy-1-methyl-1H-pyrano[4',3':4,5]oxazolo[2,3-c][1,4]oxazin-3-yl]oxy]-5,12-naphthacenedione

PNU-159682 95%

5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[(1S,3R,4aS,9S,9aR,10aS)-octahydro-9-methoxy-1-methyl-1H-pyrano[4',3':4,5]oxazolo[2,3-c][1,4]oxazin-3-yl]oxy]-, (8S,10S)-

5-hydroxy-6-tert.-butyl-1,1-pentamethylene-3,3-dimethyl-indane

inhibit,non-Hodgkin’s lymphoma,PNU159682,ADCs Toxin,PNU-159682,acute myeloid leukemia,ADC Payload,EDV nanocell,AML,Inhibitor,ADC Cytotoxin,PNU 159682,Topoisomerase,NMS249,NHL

(8S,10S)-6,8,11-Trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-(((1S,3R,4aS,9S,9aR,10aS)-9-methoxy-1-methyloctahydro-1H-pyrano[4',3':4,5]oxazolo[2,3-c][1,4]oxazin-3-yl)oxy)-7,8,9,10-tetrahydrotetracene-5,12-dione

(8S,10S)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-{[(2S,4R,6S,7S,9R,10S)-10-methoxy-6-methyl-5,8,11-trioxa-1-azatricyclo[7.4.0.02,?]tridecan-4-yl]oxy}-5,7,8,9,10,12-hexahydrotetracene-5,12-dione

202350-68-3