ChemicalBook > CAS DataBase List > 2,4-Dichloro-3-Methylacetophenone

2,4-Dichloro-3-Methylacetophenone

Product Name
2,4-Dichloro-3-Methylacetophenone
CAS No.
157652-32-9
Chemical Name
2,4-Dichloro-3-Methylacetophenone
Synonyms
2,4-Dichloro-3-Methylacetophenone;1-(2,4-Dichloro-3-methylphenyl)ethan-1-one;Ethanone, 1-(2,4-dichloro-3-methylphenyl)-
CBNumber
CB12709861
Molecular Formula
C9H8Cl2O
Formula Weight
203.07
MOL File
157652-32-9.mol
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2,4-Dichloro-3-Methylacetophenone Property

Melting point:
38 °C
Boiling point:
147-148 °C(Press: 10 Torr)
Density 
1.260±0.06 g/cm3(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H341Suspected of causing genetic defects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
D435465
Product name
2,4-Dichloro-3-methylacetophenone
Packaging
10g
Price
$1320
Updated
2021/12/16
Alichem
Product number
157652329
Product name
2',4'-Dichloro-3'-methylacetophenone
Packaging
1g
Price
$1504.9
Updated
2021/12/16
Alichem
Product number
157652329
Product name
2',4'-Dichloro-3'-methylacetophenone
Packaging
250mg
Price
$484.8
Updated
2021/12/16
Alichem
Product number
157652329
Product name
2',4'-Dichloro-3'-methylacetophenone
Packaging
500mg
Price
$823.15
Updated
2021/12/16
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2,4-Dichloro-3-Methylacetophenone Chemical Properties,Usage,Production

Uses

2,4-Dichloro-3-methylacetophenone is an intermediate used to synthesize 7-Chloro-1-cyclopropyl-1,4-dihydro-8-methyl-4-oxo-3-quinolinecarboxylic Acid (C364875) which is a medical bactericide.

Synthesis

Aluminum chloride (49.68 g, 372.60 mmol) and 2,6-dichloro toluene (50.00 g, 310.50 mmol) were added to the single-mouth flask under stir at room temperature. Then acetyl chloride (26.81 g, 341.60 mmol) is added dropwise. The reaction was heated to 40°C for 2 hours, and the reaction of the raw materials was monitored by TLC to be complete. Pour the system slowly into ice water (500mL), dilute hydrochloric acid solution(1M, 30mL) acidified, extracted with dichloromethane (150mL x 3). It was dried over anhydrous sodium sulfate and concentrated to obtain 2,4-Dichloro-3-Methylacetophenone as a colorless oil with a yield of 95%.

2,4-Dichloro-3-Methylacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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157652-32-9, 2,4-Dichloro-3-MethylacetophenoneRelated Search:


  • 2,4-Dichloro-3-Methylacetophenone
  • Ethanone, 1-(2,4-dichloro-3-methylphenyl)-
  • 1-(2,4-Dichloro-3-methylphenyl)ethan-1-one
  • 157652-32-9