CID 16020046

Uses

Product Name: CID 16020046
CAS No.: 834903-43-4
Chemical Name: CID 16020046
Synonyms: CS-1189;C390-0219;CID 16020046;CID16020046 (CID 16020046);CID 16020046, 10 mM in DMSO;CID16020046;CID 16020046;CID 16020046;4-(4-(3-Hydroxyphenyl)-6-oxo-3-(p-tolyl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5(1H)-yl)benzoic acid;4-[4-(3-Hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-4,6-dihydropyrrolo[3,4-c]pyrazol-5(1H)-yl]benzoic acid;4-[4,6-Dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]-benzoic acid;Benzoic acid, 4-[4,6-dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]-
CBNumber: CB12715619
Molecular Formula: C25H19N3O4
Formula Weight: 425.44
MOL File: 834903-43-4.mol

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CID 16020046 Property

Boiling point:: 748.1±60.0 °C(Predicted)
Density: 1.425±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: soluble1mg/mL, clear (warmed)
pka: 4.27±0.10(Predicted)
form: powder
color: white to beige

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Safety

Hazard Codes: Xi
Risk Statements: 36/38
Safety Statements: 26
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0805
Product name: CID16020046
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $151
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0805
Product name: CID16020046
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $537
Updated: 2024/03/01

Cayman Chemical

Product number: 15247
Product name: CID16020046
Purity: ≥98%
Packaging: 1mg
Price: $36
Updated: 2024/03/01

Cayman Chemical

Product number: 15247
Product name: CID16020046
Purity: ≥98%
Packaging: 5mg
Price: $112
Updated: 2024/03/01

Cayman Chemical

Product number: 15247
Product name: CID16020046
Purity: ≥98%
Packaging: 10mg
Price: $172
Updated: 2024/03/01

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CID 16020046 Chemical Properties,Usage,Production

Uses

CID 16020046 is a selective GPR55 antagonist. It Inhibits LPI-induced Ca2+ signaling, ERK1/2 phosphorylation and GPR55-mediated transcription factor activation. It displays weak inhibition of acetylcholinesterase, μ-opioid receptor, KCNH2 and hERG. It decreases LPI-induced GPR55 internalization.

Uses

CID 16020046 is a selective GPR55 antagonist. It Inhibits LPI-induced Ca2+ signaling, ERK1/2 phosphorylation and GPR55-mediated transcription factor activation. It displays weak inhibition of acetylcholinesterase, μ-opioid receptor, KCNH2 and hERG. It decreases LPI-induced GPR55 internalization.

Biochem/physiol Actions

CID16020046 is a potent and a selective GPR55 antagonist that inhibits GPR55-mediated ERK1/2 phosphorylation. CID16020046 inhibits LPI-induced Ca2+ signaling in HEK-GPR55 cells.

storage

Store at +4°C

CID 16020046 Preparation Products And Raw materials

Raw materials

Preparation Products

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CID 16020046 Suppliers

China 65 India 1 United Kingdom 2 United States 12 Global 80

Novachemistry

Tel: 44-20819178-90 02081917890
Fax: (0)2080432064
Email: info@novachemistry.com
Country: United Kingdom
ProdList: 4381
Advantage: 58

Tocris Bioscience

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Email: customerservice@tocris.co.uk
Country: United Kingdom
ProdList: 5726
Advantage: 77

834903-43-4, CID 16020046Related Search:

Uracil Dihydroxybenzoic acid Diphenylphosphine oxide

4-[4-(3-Hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-4,6-dihydropyrrolo[3,4-c]pyrazol-5(1H)-yl]benzoic acid

CID16020046 (CID 16020046)

Benzoic acid, 4-[4,6-dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]-

CID 16020046

4-[4,6-Dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]-benzoic acid

CS-1189

CID16020046;CID 16020046;CID 16020046

C390-0219

4-(4-(3-Hydroxyphenyl)-6-oxo-3-(p-tolyl)-4,6-dihydropyrrolo[3,4-c]pyrazol-5(1H)-yl)benzoic acid

CID 16020046,cells,CID16020046,wound,Ca2+,inhibit,ERK1/2,GPR55,hERG,acetylcholinesterase,HEK,CID-16020046,function,phosphorylation,KCNH2,LPI,healing,endothelial,platelet,Inhibitor,HMVEC,lysophosphatidylinositol,m-opioid,G protein-coupled receptor 55

CID 16020046, 10 mM in DMSO

834903-43-4