ChemicalBook > CAS DataBase List > 11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2

11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2

Product Name
11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2
CAS No.
53658-98-3
Chemical Name
11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2
Synonyms
AY 24609;11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2;9-OXO-15R-HYDROXY-16,16-DIMETHYL-PROSTA-5Z,13E-DIEN-1-OIC ACID;Prosta-5,13-dien-1-oic acid, 15-hydroxy-16,16-dimethyl-9-oxo-, (5Z,13E,15R)-
CBNumber
CB1274529
Molecular Formula
C22H36O4
Formula Weight
364.52
MOL File
53658-98-3.mol
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11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2 Property

solubility 
DMF: >100 mg/ml (from PGE2); DMSO: >100 mg/ml (from PGE2); Ethanol: >100 mg/ml (from PGE2); PBS pH 7.2: >5 mg/ml (from PGE2)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

H336May cause drowsiness or dizziness

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
14570
Product name
11-deoxy-16,16-dimethyl Prostaglandin E2
Purity
≥98%
Packaging
1mg
Price
$64
Updated
2024/03/01
Cayman Chemical
Product number
14570
Product name
11-deoxy-16,16-dimethyl Prostaglandin E2
Purity
≥98%
Packaging
5mg
Price
$280
Updated
2024/03/01
Cayman Chemical
Product number
14570
Product name
11-deoxy-16,16-dimethyl Prostaglandin E2
Purity
≥98%
Packaging
10mg
Price
$497
Updated
2024/03/01
TRC
Product number
A795100
Product name
AY24609
Packaging
2.5mg
Price
$560
Updated
2021/12/16
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11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2 Chemical Properties,Usage,Production

Description

11-deoxy-16,16-dimethyl PGE2 is a stable synthetic analog of PGE2. It is an agonist for both EP2 and EP3 receptors. It is an effective inhibitor of gastric acid secretion and ulcer formation in the rat, with ED50 values of 1 mg/kg and 0.021 mg/kg respectively. It is 900 times more potent than PGF2α in the contraction of human respiratory tract smooth muscle in vitro.

Uses

AY 24609 is an analogue of PGE2 and a selective EP2 and EP3 receptors agonist. It also inhibits gastric acid secretion and ulcer formation in rat.

Definition

ChEBI: 11-Deoxy-16,16-dimethyl-PGE2 is a prostanoid.

11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2 Preparation Products And Raw materials

Raw materials

Preparation Products

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11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2 Suppliers

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53658-98-3, 11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2Related Search:

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  • 9-OXO-15R-HYDROXY-16,16-DIMETHYL-PROSTA-5Z,13E-DIEN-1-OIC ACID
  • 11-DEOXY-16,16-DIMETHYL PROSTAGLANDIN E2
  • AY 24609
  • Prosta-5,13-dien-1-oic acid, 15-hydroxy-16,16-dimethyl-9-oxo-, (5Z,13E,15R)-
  • 53658-98-3