ChemicalBook > CAS DataBase List > ML335

ML335

Product Name
ML335
CAS No.
1069498-96-9
Chemical Name
ML335
Synonyms
ML335;CYM51010;CID23723457;ML 335,ML335;CYM51010(ML335);Ethyl 1-(4-acetamidobenzyl)-4- phenethylpiperidine-4-carboxylate;ethyl 1-[(4-acetamidophenyl)methyl]-4-(2-phenylethyl)piperidine-4-carboxylate;1-[[4-(Acetylamino)phenyl]methyl]-4-(2-phenylethyl)-4-Piperidinecarboxylic acid ethyl ester;4-Piperidinecarboxylic acid, 1-[[4-(acetylamino)phenyl]methyl]-4-(2-phenylethyl)-, ethyl ester
CBNumber
CB12750520
Molecular Formula
C25H32N2O3
Formula Weight
408.53
MOL File
1069498-96-9.mol
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ML335 Property

storage temp. 
2-8°C
solubility 
DMSO: soluble10mg/mL, clear
form 
powder
color 
white to beige
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Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0980
Product name
CYM51010
Purity
≥98% (HPLC)
Packaging
5mg
Price
$119
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0980
Product name
CYM51010
Purity
≥98% (HPLC)
Packaging
25mg
Price
$594
Updated
2024/03/01
Cayman Chemical
Product number
15196
Product name
ML-335
Purity
≥98%
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
15196
Product name
ML-335
Purity
≥98%
Packaging
5mg
Price
$118
Updated
2024/03/01
Cayman Chemical
Product number
15196
Product name
ML-335
Purity
≥98%
Packaging
10mg
Price
$193
Updated
2024/03/01
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ML335 Chemical Properties,Usage,Production

Description

The μ-opioid receptor (OPRM1) is the primary site of action for morphine and other opioids associated with the treatment of pain. The occupancy of δ-opioid receptors (OPRD1) by antagonists has been shown to enhance OPRM1 binding and signaling activity. Because heteromerization of OPRM1 and OPRD1 is thought to be a potential mechanism by which this occurs, compounds are being sought that selectively activate OPRM1-OPRD1 heterodimerization while alleviating the unwanted effects associated with prolonged opiate use. ML-335 is the first identified agonist for OPRM1-OPRD1 heterodimerization (EC50 = 403 nM) that demonstrates selectivity over the individual OPRM1 and OPRD1 receptors and the serotonin HT5A receptor (EC50s = 14.9, 1.1, and >40 μM, respectively).

Uses

ML335, is a selective activator of both TREK-1 and TREK-2.

Uses

ML-335 is an agonist for μ-opioid receptor (OPRM1)- δ-opioid receptors (OPRD1) heterodimerization.

ML335 Preparation Products And Raw materials

Raw materials

Preparation Products

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ML335 Suppliers

China 48 United States 8 Global 56
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
United States Biological
Tel
--
Fax
--
Email
sales@advtechind.com
Country
United States
ProdList
6075
Advantage
58
ApexBio Technology
Tel
--
Fax
--
Email
sales@apexbt.com
Country
United States
ProdList
6251
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80

1069498-96-9, ML335Related Search:


  • 1-[[4-(Acetylamino)phenyl]methyl]-4-(2-phenylethyl)-4-Piperidinecarboxylic acid ethyl ester
  • CID23723457
  • CYM51010
  • ML335
  • 4-Piperidinecarboxylic acid, 1-[[4-(acetylamino)phenyl]methyl]-4-(2-phenylethyl)-, ethyl ester
  • CYM51010(ML335)
  • Ethyl 1-(4-acetamidobenzyl)-4- phenethylpiperidine-4-carboxylate
  • ML 335,ML335
  • ethyl 1-[(4-acetamidophenyl)methyl]-4-(2-phenylethyl)piperidine-4-carboxylate
  • 1069498-96-9