MLS-0315848 hydrochloride

Product Name: MLS-0315848 hydrochloride
CAS No.: 1135318-57-8
Chemical Name: MLS-0315848 hydrochloride
Synonyms: ML095;ML095 HCL;MLS-0315848 hcl;ML095 hydrochloride;MLS-0315848 hydrochloride;CID-25067483 hydrochloride;ML-095 hydrochloride, 10 mM in DMSO;1-(3,4-dihydroxyphenyl)-2-(2-ethylimidazol-1-yl)ethanone;1-(3,4-Dihydroxyphenyl)-2-(3-ethyl-1H-pyrazol-1-yl)ethanone Hydrochloride;1-(3,4-Dihydroxyphenyl)-2-(2-ethyl-1H-imidazol-1-yl)-Ethanone hydrochloride
CBNumber: CB12750702
Molecular Formula: C13H15ClN2O3
Formula Weight: 282.72
MOL File: 1135318-57-8.mol

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MLS-0315848 hydrochloride Property

storage temp.: 2-8°C
solubility: H2O: soluble5mg/mL, clear
form: powder
color: white to beige

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Safety

Hazard Codes: Xn
Risk Statements: 22-37/38-41
Safety Statements: 26-39
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 15173
Product name: ML-095 (hydrochloride)
Purity: ≥98%
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 15173
Product name: ML-095 (hydrochloride)
Purity: ≥98%
Packaging: 5mg
Price: $118
Updated: 2024/03/01

Cayman Chemical

Product number: 15173
Product name: ML-095 (hydrochloride)
Purity: ≥98%
Packaging: 10mg
Price: $193
Updated: 2024/03/01

Cayman Chemical

Product number: 15173
Product name: ML-095 (hydrochloride)
Purity: ≥98%
Packaging: 25mg
Price: $374
Updated: 2024/03/01

TRC

Product number: D454515
Product name: 1-(3,4-Dihydroxyphenyl)-2-(3-ethyl-1H-pyrazol-1-yl)ethanoneHydrochloride
Packaging: 1mg
Price: $50
Updated: 2021/12/16

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MLS-0315848 hydrochloride Chemical Properties,Usage,Production

Uses

1-(3,4-Dihydroxyphenyl)-2-(3-ethyl-1H-pyrazol-1-yl)ethanone Hydrochloride is a biochemical inhibitor of placental alkaline phosphatase (PLAP) and is used to elucidate the key biological functions and natural substrates of human PLAP.

Biological Activity

ml-095 (hydrochloride) is a specific plap inhibitor [1].alkaline phosphatases are hydrolase enzymes responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. there are three isozymes of alkaline phosphatases: placental alkaline phosphatase (plap), intestinal alkaline phosphatase (iap), and tissue non-specific alkaline phosphatase (tnap). placental alkaline phosphatase (plap) is highly expressed in primate placental tissue and the biological function is still unknown. however, plap-like enzymes are detected in serum of patients with primary testicular tumors, in particular seminoma and other cancers [1].ml-095 (cid-25067483) is a biochemical inhibitor of plap and will be useful to elucidate the key biological functions and natural substrates of human plap. ml095 is a specific plap inhibitor and inhibited plap, tnap and iap with ic50 values of 2.1, >100 and 53 μm, respectively. ml095 exhibited greater than 25-fold selectivity over tissue non-specific alkaline phosphatase (tnap) and intestinal alkaline phosphatase (iap) [1].

References

[1]. lanier m, cashman j, sergienko e, et al. placental alkaline phosphatase (plap) luminescent hts assay - probe 2.

MLS-0315848 hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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MLS-0315848 hydrochloride Suppliers

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1135318-57-8, MLS-0315848 hydrochlorideRelated Search:

1-(3,4-Dihydroxyphenyl)-2-(2-ethyl-1H-imidazol-1-yl)-Ethanone hydrochloride

CID-25067483 hydrochloride

ML095 hydrochloride

MLS-0315848 hydrochloride

1-(3,4-Dihydroxyphenyl)-2-(3-ethyl-1H-pyrazol-1-yl)ethanone Hydrochloride

MLS-0315848 hcl

ML095 HCL

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1135318-57-8

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