ChemicalBook > CAS DataBase List > NSC 150117 hydrochloride
NSC 150117 hydrochloride
- Product Name
- NSC 150117 hydrochloride
- CAS No.
- 95130-23-7
- Chemical Name
- NSC 150117 hydrochloride
- Synonyms
- (E/Z)-BCI;BCI (hydrochloride);(E)-BCI hydrochloride;(E/Z)-BCI hydrochloride;NSC 150117 hydrochloride;BCI hydrochloride - NSC 150117 hydrochloride;(2Z)-2-benzylidene-3-(cyclohexylamino)-3H-inden-1-one;2-benzylidene-3-(cyclohexylamino)-1-Indanone hydrochloride;(E)-2-benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one;3-(cyclohexylamino)-2,3-dihydro-2-(phenylmethylene)-1Hinden-1-one
- CBNumber
- CB12756032
- Molecular Formula
- C22H24ClNO
- Formula Weight
- 353.885
- MOL File
- 95130-23-7.mol
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NSC 150117 hydrochloride Property
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble10mg/mL, clear
- form
- powder
- color
- white to beige
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- B4313
- Product name
- (E/Z)-BCI hydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $254
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- B4313
- Product name
- (E/Z)-BCI hydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $695.1
- Updated
- 2025/07/31
Cayman Chemical
- Product number
- 21945
- Product name
- BCI (hydrochloride)
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21945
- Product name
- BCI (hydrochloride)
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $202
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21945
- Product name
- BCI (hydrochloride)
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $384
- Updated
- 2024/03/01
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NSC 150117 hydrochloride Chemical Properties,Usage,Production
Uses
(E/Z)-BCI hydrochloride has been used:
- to evaluate the role of the Duox-H2O2-Dusp6 derepression signaling pathway in heart regeneration
- as an MKP-1 inhibitor to investigate the role of MKP-1 on bexarotent-induced effects
- as a dual specificity phosphatase 6 (DUSP6) inhibitor to study its effects on the proliferation of SKOV3 cells
Biochem/physiol Actions
BCI is an allosteric inhibitor of Dusp6 that acts within the phosphatase domain to prevent the catalytic stimulation of phosphatase activity induced by ERK2 substrate binding. BCI also hyperactivates FGF signaling, since Dusp6 functions as a feedback regulator of FGF signaling.
NSC 150117 hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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NSC 150117 hydrochloride Suppliers
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