6-NITROIMIDAZO[1,2-A]PYRIDINE
- Product Name
- 6-NITROIMIDAZO[1,2-A]PYRIDINE
- CAS No.
- 25045-82-3
- Chemical Name
- 6-NITROIMIDAZO[1,2-A]PYRIDINE
- Synonyms
- 6-NITROIMIDAZO[1,2-A]PYRIDINE;6-nitrosoimidazo[1,2-a]pyridine;IMidazo[1,2-a]pyridine, 6-nitro-
- CBNumber
- CB1278345
- Molecular Formula
- C7H5N3O2
- Formula Weight
- 163.13
- MOL File
- 25045-82-3.mol
6-NITROIMIDAZO[1,2-A]PYRIDINE Property
- Melting point:
- 229-231°
- Density
- 1.49±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 3.70±0.50(Predicted)
- Appearance
- Yellow to brown Solid
- InChI
- InChI=1S/C7H5N3O2/c11-10(12)6-1-2-7-8-3-4-9(7)5-6/h1-5H
- InChIKey
- RXZZQEFTZIHXRI-UHFFFAOYSA-N
- SMILES
- C12=NC=CN1C=C([N+]([O-])=O)C=C2
- CAS DataBase Reference
- 25045-82-3
Safety
- HazardClass
- IRRITANT
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 045755
- Product name
- 6-Nitroimidazo[1,2-a]pyridine
- Purity
- 95+%
- Packaging
- 5g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- Z4497
- Product name
- 6-Nitroimidazo[1,2-a]pyridine
- Packaging
- 1g
- Price
- $70
- Updated
- 2021/12/16
- Product number
- 045755
- Product name
- 6-Nitroimidazo[1,2-a]pyridine
- Purity
- 95+%
- Packaging
- 25g
- Price
- $150
- Updated
- 2021/12/16
- Product number
- BP-20256
- Product name
- 6-nitro-imidazo[1,2-a]pyridine
- Purity
- 96%
- Packaging
- 5G
- Price
- $290
- Updated
- 2021/12/16
- Product number
- 188692
- Product name
- 6-NitroH-imidazo[1,2-a]pyridine
- Packaging
- 10g
- Price
- $298
- Updated
- 2021/12/16
6-NITROIMIDAZO[1,2-A]PYRIDINE Chemical Properties,Usage,Production
Synthesis
4214-76-0
2032-35-1
25045-82-3
In a 250 mL single-neck flask, bromoacetaldehyde diethyl acetal (42.5 g, 215.7 mmol) was dissolved in a mixture of 1 mol/L hydrochloric acid (120 mL) and ethanol (20 mL) and stirred at room temperature for 30 minutes. It was then heated to reflux and stirred continuously until the solution became clear. Upon completion of the reaction, the solution was cooled to room temperature and the pH was adjusted to near neutral with sodium bicarbonate solution. 2-Amino-5-nitropyridine (15.0 g, 107.8 mmol) was added and the reaction was stirred overnight at room temperature. At the end of the reaction, extraction was carried out with ethyl acetate (100 mL×3), the organic phases were combined, and the solvent was removed by concentration under reduced pressure. The crude product was purified by silica gel column chromatography (eluent ratio: petroleum ether:ethyl acetate = 2:1) to afford 13.7 g of yellow-brown crystalline 6-nitroimidazo[1,2-a]pyridine in 77.6% yield.
References
[1] Patent: CN107129496, 2017, A. Location in patent: Paragraph 0026-0028; 0014-0016; 0020-0022
6-NITROIMIDAZO[1,2-A]PYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
6-NITROIMIDAZO[1,2-A]PYRIDINE Suppliers
- Tel
- --
- Fax
- --
- info@specs.net
- Country
- The Netherlands
- ProdList
- 6833
- Advantage
- 70
View Lastest Price from 6-NITROIMIDAZO[1,2-A]PYRIDINE manufacturers
- Product
- 6-NITROIMIDAZO[1,2-A]PYRIDINE 25045-82-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2019-12-25