4-BENZYL-MORPHOLINE-2-CARBOXYLIC ACID

Product Name: 4-BENZYL-MORPHOLINE-2-CARBOXYLIC ACID
CAS No.: 769087-80-1
Chemical Name: 4-BENZYL-MORPHOLINE-2-CARBOXYLIC ACID
Synonyms: 4-Benzyl-2-Morpholinecarboxylic acid;4-BENZYL-MORPHOLINE-2-CARBOXYLIC ACID;4-Benzyl-morpholine-2-carboxylic acid ,97%;2-Morpholinecarboxylic acid, 4-(phenylmethyl)-
CBNumber: CB1280094
Molecular Formula: C12H15NO3
Formula Weight: 221.25
MOL File: 769087-80-1.mol

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4-BENZYL-MORPHOLINE-2-CARBOXYLIC ACID Property

Boiling point:: 372.7±42.0 °C(Predicted)
Density: 1.235±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 2.57±0.20(Predicted)
form: Solid
color: White to Off-White
Stability:: Hygroscopic

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Safety

HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FB139826
Product name: 4-Benzylmorpholine-2-carboxylic acid
Packaging: 1g
Price: $70
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB139826
Product name: 4-Benzylmorpholine-2-carboxylic acid
Packaging: 2g
Price: $121
Updated: 2021/12/16

Matrix Scientific

Product number: 082779
Product name: 4-Benzylmorpholine-2-carboxylic acid
Purity: 97%
Packaging: 1g
Price: $124
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H58-1-BU
Product name: 4-Benzylmorpholine-2-carboxylic acid
Packaging: 250mg
Price: $175
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB139826
Product name: 4-Benzylmorpholine-2-carboxylic acid
Packaging: 5G
Price: $241
Updated: 2021/12/16

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4-BENZYL-MORPHOLINE-2-CARBOXYLIC ACID Chemical Properties,Usage,Production

Uses

4-Benzyl-morpholine-2-carboxylic is used in the synthesis of novel morpholine conjugated benzophenone analogs and evaluation of antagonistic role against neoplastic development.

Synthesis

147767-51-9

769087-80-1

Step B. Synthesis of 4-benzylmorpholine-2-carboxylic acid. 4-Benzylmorpholine-2-carbonitrile (20.2 g, 100 mmol) was dissolved in toluene (60 mL), followed by the slow addition of 6 M hydrochloric acid solution (100 mL, 600 mmol). The reaction mixture was heated to 110 °C and kept at reflux for 1.5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and stirring was continued for 18 hours. The precipitated solid was collected by filtration to afford the target product 4-benzyl-morpholine-2-carboxylic acid (22 g, 99% yield) as a white solid.

References

[1] Patent: WO2015/164508, 2015, A1. Location in patent: Page/Page column 48-49
[2] Patent: WO2011/58478, 2011, A1. Location in patent: Page/Page column 54-55

4-BENZYL-MORPHOLINE-2-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Monoethanolamine Potassium tert-butoxide Benzyl chloride N,N-Dimethylformamide Potassium hydroxide 2-Chloroacrylonitrile Sodium sulfate Toluene Tetrahydrofuran Diethyl ether Ethyl acetate Hydrochloric acid Sodium bicarbonate 1,2-Dimethoxyethane

Preparation Products

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4-BENZYL-MORPHOLINE-2-CARBOXYLIC ACID Suppliers

China 93 Germany 1 India 1 United Kingdom 5 United States 13 Global 113

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View Lastest Price from 4-BENZYL-MORPHOLINE-2-CARBOXYLIC ACID manufacturers

Career Henan Chemical Co

Product: 4-BENZYL-MORPHOLINE-2-CARBOXYLIC ACID 769087-80-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2018-12-24

769087-80-1, 4-BENZYL-MORPHOLINE-2-CARBOXYLIC ACIDRelated Search:

4-BENZYL-MORPHOLINE-2-CARBOXYLIC ACID

2-Morpholinecarboxylic acid, 4-(phenylmethyl)-

4-Benzyl-morpholine-2-carboxylic acid ,97%

4-Benzyl-2-Morpholinecarboxylic acid

769087-80-1

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