4-BENZYL-2-MORPHOLINECARBOXYLIC ACID HYDROCHLORIDE
- Product Name
- 4-BENZYL-2-MORPHOLINECARBOXYLIC ACID HYDROCHLORIDE
- CAS No.
- 135072-15-0
- Chemical Name
- 4-BENZYL-2-MORPHOLINECARBOXYLIC ACID HYDROCHLORIDE
- Synonyms
- 4-Benzyl-2-morpholinecarboxylicacidHCl;4-Benzyl-2-carboxymorpholine hydrochloride;BENZYL(N-)-MORPHOLINE-2-CARBOXYLIC ACID HCL;4-BENZYL-2-MORPHOLINECARBOXYLIC ACID HYDROCHLORIDE;4-BENZYL-MORPHOLINE-2-CARBOXYLIC ACID HYDROCHLORIDE;4-Benzylmorpholine-2-carboxylicacidhydrochloride,97%;4-Benzyl-2-morpholinecarboxylic acid hydrochloride, 90+%;4-Benzyl-2-carboxymorpholine hydrochloride, 10 mM in DMSO;2-Morpholinecarboxylic acid, 4-(phenylmethyl)-, hydrochloride;4-(phenylmethyl)-2-Morpholinecarboxylic acid hydrochloride (1:1)
- CBNumber
- CB3101320
- Molecular Formula
- C12H16ClNO3
- Formula Weight
- 257.71
- MOL File
- 135072-15-0.mol
4-BENZYL-2-MORPHOLINECARBOXYLIC ACID HYDROCHLORIDE Property
- Melting point:
- 244 °C
- storage temp.
- Sealed in dry,Room Temperature
- form
- solid
- color
- Brown
Safety
- Hazard Codes
- Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 26-36/37/39
- Hazard Note
- Harmful
- HazardClass
- 6.1
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- B535568
- Product name
- 4-Benzyl-2-morpholinecarboxylicAcidHydrochloride
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR23182
- Product name
- 4-Benzylmorpholine-2-carboxylicacidhydrochloride
- Packaging
- 1g
- Price
- $34
- Updated
- 2021/12/16
- Product number
- 4H21-5-Z5
- Product name
- 4-Benzylmorpholine-2-carboxylic acid hydrochloride
- Packaging
- 1g
- Price
- $37
- Updated
- 2021/12/16
- Product number
- OR23182
- Product name
- 4-Benzylmorpholine-2-carboxylicacidhydrochloride
- Packaging
- 250mg
- Price
- $15
- Updated
- 2021/12/16
- Product number
- 4H21-5-Z5
- Product name
- 4-Benzylmorpholine-2-carboxylic acid hydrochloride
- Packaging
- 250mg
- Price
- $16
- Updated
- 2021/12/16
4-BENZYL-2-MORPHOLINECARBOXYLIC ACID HYDROCHLORIDE Chemical Properties,Usage,Production
Synthesis
147767-51-9
135072-15-0
4-Benzylmorpholine-2-carbonitrile (64.1 g, 316.9 mmol) was used as the raw material, which was dissolved in 6 N aqueous hydrochloric acid (600 mL) and the reaction was heated to reflux for 2.5 hours. After the reaction was completed, the reaction solution was cooled to -10 °C. The precipitated solid product was collected by filtration and washed with acetone (300 mL) pre-cooled to -10 °C. The resulting solid was dried in an oven at 60 °C to afford 4-benzyl-2-morpholine carboxylic acid hydrochloride (78.7 g, 305.4 mmol, 96% yield). The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 2.18 (broad peak, -COOH), 7.67-7.65 (multiple peaks, 2H), 7.53-7.40 (multiple peaks, 3H), 4.61 (double peak, J = 10.8 Hz, 1H), 4.39 (multiple peaks, 2H), 4.05-4.94 (multiple peaks, 2H) , 3.43 (double peak, J = 12.0 Hz, 1H), 3.20-3.07 (multiple peaks, 3H).
References
[1] Patent: WO2012/128582, 2012, A2. Location in patent: Page/Page column 28
[2] Patent: WO2005/47272, 2005, A1. Location in patent: Page/Page column 48-49
[3] Organic Process Research and Development, 2009, vol. 13, # 2, p. 209 - 224
[4] Patent: WO2010/59658, 2010, A1. Location in patent: Page/Page column 225
4-BENZYL-2-MORPHOLINECARBOXYLIC ACID HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-BENZYL-2-MORPHOLINECARBOXYLIC ACID HYDROCHLORIDE manufacturers
- Product
- 4-BENZYL-2-MORPHOLINECARBOXYLIC ACID HYDROCHLORIDE 135072-15-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-02