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EQUISETIN

Product Name
EQUISETIN
CAS No.
57749-43-6
Chemical Name
EQUISETIN
Synonyms
LS-64262;EQUISETIN;Citalopram Impurity 39;(3E,5S)-3-[[(1S,2R,4aS,6R,8aR)-1,6-dimethyl-2-[(E)-prop-1-enyl]-4a,5,6,7,8,8a-hexahydro-2H-naphthalen-1-yl]-hydroxymethylidene]-5-(hydroxymethyl)-1-methylpyrrolidine-2,4-dione;2,4-Pyrrolidinedione, 5-(hydroxymethyl)-3-[hydroxy[(1S,2R,4aS,6R,8aR)-1,2,4a,5,6,7,8,8a-octahydro-1,6-dimethyl-2-(1E)-1-propen-1-yl-1-naphthalenyl]methylene]-1-methyl-, (3E,5S)-;(3E,5S)-3-{[(1S,2R,4aS,6R,8aR)-1,6-dimethyl-2-[(1E)-prop-1-en-1-yl]-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl](hydroxy)methylidene}-5-(hydroxymethyl)-1-methylpyrrolidine-2,4-dione
CBNumber
CB1281192
Molecular Formula
C22H31NO4
Formula Weight
373.49
MOL File
57749-43-6.mol
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EQUISETIN Property

Melting point:
117-118 °C
Boiling point:
556.0±50.0 °C(Predicted)
Density 
1.180±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
4.50±1.00(Predicted)
color 
Pale Beige to Light Brown
Stability:
Hygroscopic
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Safety

HS Code 
29339900
Toxicity
mouse,LD50,intraperitoneal,63mg/kg (63mg/kg),Antimicrobial Agents and Chemotherapy. Vol. 5, Pg. 634, 1974.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
18196
Product name
Equisetin
Purity
≥99%
Packaging
1mg
Price
$153
Updated
2024/03/01
Cayman Chemical
Product number
18196
Product name
Equisetin
Purity
≥99%
Packaging
5mg
Price
$684
Updated
2024/03/01
Usbiological
Product number
E3450-55
Product name
Equisetin
Packaging
1mg
Price
$390
Updated
2021/12/16
TRC
Product number
E592900
Product name
Equisetin
Packaging
0.5mg
Price
$125
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0016732
Product name
EQUISETIN
Purity
95.00%
Packaging
5MG
Price
$505.9
Updated
2021/12/16
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EQUISETIN Chemical Properties,Usage,Production

Description

Equisetin is a fungal metabolite that has been isolated from Fusarium. It inhibits HIV-1 integrase 3’ end-processing and strand transfer activities. Equisetin inhibits the ATPase activity of rat liver mitochondria and mitoplasts stimulated by 2,4-dinitrophenol (Dnp) in a concentration-dependent manner (IC50 = ~8 nM per mg of protein for both). It also inhibits ADP-stimulated respiration and the mitochondrial transport of ATP, inorganic phosphate, and succinate. Epiequisetin is phytotoxic and inhibits the germination of various seeds and growth of young seedlings.

Uses

The tetramic acid, equisetin, is produced by a number of species of Fusarium. Interest in equisetin emerged with reports of its inhibitory activity against HIV-1 integrase in vitro that was mechanistically distinct from previously described inhibitors. Equisetin inhibits 3' end-processing and strand transfer, as well as disintegration catalysed by either the full-length enzyme or the truncated integrase core.

Uses

Equisetin is tetramic acid with antibiotic and cytotoxic activity, and a potent inhibitor of HIV-1 integrase.

EQUISETIN Preparation Products And Raw materials

Raw materials

Preparation Products

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EQUISETIN Suppliers

China 53 India 1 United Kingdom 6 United States 12 Global 72
EMMX Biotechnology LLC
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888-539-0666
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info@emmx.com
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United States
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BOC Sciences
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16314854226; +16314854226
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TargetMol Chemicals Inc.
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marketing@targetmol.com
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TargetMol Chemicals Inc.
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Aladdin Scientific
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ApexBio Technology
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Cayman Chemical Company
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View Lastest Price from EQUISETIN manufacturers

Career Henan Chemical Co
Product
EQUISETIN 57749-43-6
Price
US $1.00/g
Min. Order
1g
Purity
≥98%
Supply Ability
g/kg/Ton
Release date
2019-12-25

57749-43-6, EQUISETINRelated Search:

EQUISETIN 1-METHYL-PYRROLIDINE-2,4-DIONE 5-Hydroxymethylpyrrolidin-2-one 2,4-Pyrrolidinedione

  • EQUISETIN
  • LS-64262
  • 2,4-Pyrrolidinedione, 5-(hydroxymethyl)-3-[hydroxy[(1S,2R,4aS,6R,8aR)-1,2,4a,5,6,7,8,8a-octahydro-1,6-dimethyl-2-(1E)-1-propen-1-yl-1-naphthalenyl]methylene]-1-methyl-, (3E,5S)-
  • (3E,5S)-3-[[(1S,2R,4aS,6R,8aR)-1,6-dimethyl-2-[(E)-prop-1-enyl]-4a,5,6,7,8,8a-hexahydro-2H-naphthalen-1-yl]-hydroxymethylidene]-5-(hydroxymethyl)-1-methylpyrrolidine-2,4-dione
  • Citalopram Impurity 39
  • (3E,5S)-3-{[(1S,2R,4aS,6R,8aR)-1,6-dimethyl-2-[(1E)-prop-1-en-1-yl]-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl](hydroxy)methylidene}-5-(hydroxymethyl)-1-methylpyrrolidine-2,4-dione
  • 57749-43-6
  • C22H31NO4