RSPO1
- Product Name
- RSPO1
- Chemical Name
- RSPO1
- Synonyms
- RSPO;RSPO1;HRspo1;FLJ40906;CRISTIN3;RSPONDIN;R-spondin 1;R-SPONDIN-1 human;Roof plate-specific spondin-1;Recombinant Human RSPO1 Protein, His Tag
- CBNumber
- CB12912843
- Formula Weight
- 0
- MOL File
- Mol file
RSPO1 Property
- storage temp.
- -20°C
- form
- lyophilized
- color
- white
- biological source
- human
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- SRP3292
- Product name
- R-SPONDIN-1 human
- Purity
- recombinant, expressed in CHO cells, ≥95% (SDS-PAGE), ≥95% (HPLC)
- Packaging
- 20μG
- Price
- $380
- Updated
- 2025/07/31
- Product number
- SRP6487
- Product name
- R spondin-1 human
- Purity
- recombinant, expressed in HEK 293 cells, ≥98% (SDS-PAGE)
- Packaging
- 10μG
- Price
- $330
- Updated
- 2022/05/15
- Product number
- 156572
- Product name
- R-Spondin 1
- Packaging
- 10ug
- Price
- $350
- Updated
- 2021/12/16
- Product number
- 156571
- Product name
- R-Spondin 1
- Packaging
- 10ug
- Price
- $350
- Updated
- 2021/12/16
- Product number
- 358605
- Product name
- RSPO1
- Packaging
- 48Tests
- Price
- $588
- Updated
- 2021/12/16
RSPO1 Chemical Properties,Usage,Production
General Description
R-Spondin-1 (Rspo-1) belongs to the (Rspo) family of Wnt modulators. Currently, the (Rspo) family consists of four structurally related secreted ligands (Rspo 1-4), all containing furin-like and thrombospondin structural domains. Rspo-1 is expressed in certain areas of the developing central nervous system, as well as in adrenal glands, ovary, testis, thyroid, and trachea. Recombinant human R-Spondin-1 is a 26.7kDa protein consisting of 243 amino acid residues. Due to glycosylation, R-Spondin-1 migrates at an apparent molecular weight of approximately 40.0kDa by SDS PAGE analysis under reducing conditions.
Biochem/physiol Actions
Rspo (R-Spondin) can interact with the Frizzled/LRP6 (LDL receptor related protein 6) receptor complex in a manner that stimulates the Wnt/beta-catenin signaling pathway. Disruption of Rspo-1 gene causes recessive syndrome with XX sex reversal, palmoplantar hyperkeratosis and predisposition to squamous cell carcinoma of the skin. Rspo-1 is also associated with radioresistance of tumor cells.
RSPO1 Preparation Products And Raw materials
Raw materials
Preparation Products
RSPO1 Suppliers
- Tel
- --
- Fax
- --
- Country
- United States
- ProdList
- 6773
- Advantage
- 87