TNFSF4
- Product Name
- TNFSF4
- Chemical Name
- TNFSF4
- Synonyms
- Gp34;CD252;OX40L;OX4OL;TNLG2B;TNFSF4;Txgp1l;CD134L;OX40 Ligand human;Recombinant Human OX40L/TNFSF4 Protein, His Tag
- CBNumber
- CB12973176
- Formula Weight
- 0
- MOL File
- Mol file
TNFSF4 Property
- storage temp.
- -20°C
- form
- lyophilized
- color
- white to off-white
- biological source
- human
N-Bromosuccinimide Price
- Product number
- SRP3133
- Product name
- OX40 Ligand human
- Purity
- recombinant, expressed in Hi-5 Insect cells, ≥97% (SDS-PAGE), ≥97% (HPLC), suitable for cell culture
- Packaging
- 10μG
- Price
- $369
- Updated
- 2025/07/31
TNFSF4 Chemical Properties,Usage,Production
Biological Activity
OX40L signals specifically through the OX40 receptor, which is expressed predominantly on CD4+T cells but also on certain activated CD8+T cells. OX40/OX40L functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of regulated on activation, normal T cell expressed and secreted (RANTES) or chemokine ligand 5 (CCL5), interleukins-2 and -3, and interferon-γ (IFNγ). OX40/OX40L signaling plays an important role in immuno-regulatory communication and immune-tolerance. Polymorphisms in the TNFSF4 gene have been associated with autoimmune thyroid diseases (AITDs), rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and systemic sclerosis (SSc).
TNFSF4 Preparation Products And Raw materials
Raw materials
Preparation Products
TNFSF4 Suppliers
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