DC_517

Product Name: DC_517
CAS No.: 500017-70-9
Chemical Name: DC_517
Synonyms: DC_517;CS-2082;DC_517 (DC-517);2-Propanol, 1-[2-(9H-carbazol-9-yl)-1-(9H-carbazol-9-ylmethyl)ethoxy]-3-[(1-methylethyl)amino]-
CBNumber: CB13041399
Molecular Formula: C33H35N3O2
Formula Weight: 505.65
MOL File: 500017-70-9.mol

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DC_517 Property

Boiling point:: 727.9±60.0 °C(Predicted)
Density: 1.20±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : ≥ 50 mg/mL (98.88 mM);Water : < 0.1 mg/mL (insoluble)
form: Solid
pka: 13.88±0.20(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-4587
Product name: DC_517
Purity: 99.66%
Packaging: 5mg
Price: $420
Updated: 2021/12/16

ChemScene

Product number: CS-4587
Product name: DC_517
Purity: 99.66%
Packaging: 10mg
Price: $720
Updated: 2021/12/16

ChemScene

Product number: CS-4587
Product name: DC_517
Purity: 99.66%
Packaging: 50mg
Price: $2160
Updated: 2021/12/16

Crysdot

Product number: CD31001760
Product name: DC_517
Purity: 98+%
Packaging: 50mg
Price: $1250
Updated: 2021/12/16

Crysdot

Product number: CD31001760
Product name: DC_517
Purity: 98+%
Packaging: 5mg
Price: $243
Updated: 2021/12/16

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DC_517 Chemical Properties,Usage,Production

Uses

DC_517 is a DNA methyltransferase 1 (DNMT1) inhibitor, with an IC50 and a Kd of 1.7 μM and 0.91 μM, respectively.

IC 50

DNMT1: 0.91 μM (Kd); DNMT1: 1.7 μM (IC₅₀)

References

[1] Chen S, et al. Identifying novel selective non-nucleoside DNA methyltransferase 1 inhibitors through docking-based virtual screening. J Med Chem. 2014 Nov 13;57(21):9028-9041. DOI:10.1021/jm501134e

DC_517 Preparation Products And Raw materials

Raw materials

Preparation Products

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DC_517 Suppliers

China 23 United States 7 Global 30

Musechem

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Cckinase, Inc.

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TargetMol Chemicals Inc.

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500017-70-9, DC_517Related Search:

CS-2082

DC_517 (DC-517)

DC_517

2-Propanol, 1-[2-(9H-carbazol-9-yl)-1-(9H-carbazol-9-ylmethyl)ethoxy]-3-[(1-methylethyl)amino]-

500017-70-9