ChemicalBook > CAS DataBase List > 2-Chloro-6-methoxypurine

2-Chloro-6-methoxypurine

Product Name
2-Chloro-6-methoxypurine
CAS No.
1198-46-5
Chemical Name
2-Chloro-6-methoxypurine
Synonyms
2-Chloro-6-methoxypurine;2-Chloro-6-methoxy-9H-purine;2-chloro-6-methoxy-7H-purine;9H-Purine, 2-chloro-6-methoxy-
CBNumber
CB13042194
Molecular Formula
C6H5ClN4O
Formula Weight
184.58
MOL File
1198-46-5.mol
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2-Chloro-6-methoxypurine Property

storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C597435
Product name
2-Chloro-6-methoxypurine
Packaging
50mg
Price
$200
Updated
2021/12/16
AK Scientific
Product number
8796CC
Product name
2-Chloro-6-methoxypurine
Packaging
1g
Price
$174
Updated
2021/12/16
Apolloscientific
Product number
OR471479
Product name
2-Chloro-6-methoxypurine
Packaging
250mg
Price
$292
Updated
2021/12/16
SynQuest Laboratories
Product number
4H56-5-LA
Product name
2-Chloro-6-methoxypurine
Packaging
250mg
Price
$346
Updated
2021/12/16
Apolloscientific
Product number
OR471479
Product name
2-Chloro-6-methoxypurine
Packaging
1g
Price
$756
Updated
2021/12/16
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2-Chloro-6-methoxypurine Chemical Properties,Usage,Production

Synthesis

124-41-4

5451-40-1

1198-46-5

To a solution of 2,6-dichloro-9H-purine (1 g, 5.29 mmol) in methanol (15 mL) was added a methanolic solution of 25% sodium methanolate (1.26 mL, 5.89 mmol). The reaction mixture was heated to 80 °C and kept for 1 h, followed by cooling to room temperature. The resulting precipitate was collected by filtration, washed with ice-cold methanol and dried to afford 2-chloro-6-methoxypurine 920 mg (94% yield) as a white solid. Mass spectrometry analysis showed m/z 185.36 [M + 1].

References

[1] ACS Medicinal Chemistry Letters, 2015, vol. 6, # 5, p. 584 - 589
[2] Patent: WO2016/130920, 2016, A2. Location in patent: Page/Page column 123
[3] Tetrahedron Letters, 2015, vol. 56, # 44, p. 6019 - 6021
[4] Molecules, 2011, vol. 16, # 7, p. 5840 - 5860

2-Chloro-6-methoxypurine Preparation Products And Raw materials

Raw materials

Preparation Products

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1198-46-5, 2-Chloro-6-methoxypurineRelated Search:


  • 2-Chloro-6-methoxypurine
  • 2-Chloro-6-methoxy-9H-purine
  • 9H-Purine, 2-chloro-6-methoxy-
  • 2-chloro-6-methoxy-7H-purine
  • 1198-46-5