ChemicalBook > CAS DataBase List > 2-CHLORO-6-METHOXYPYRAZINE

2-CHLORO-6-METHOXYPYRAZINE

Product Name
2-CHLORO-6-METHOXYPYRAZINE
CAS No.
33332-30-8
Chemical Name
2-CHLORO-6-METHOXYPYRAZINE
Synonyms
C90117;6-Methoxy-2-chloropyrazine;2-Methoxy-6-chloropyrazine;2-CHLORO-6-METHOXYPYRAZINE;Pyrazine, 2-chloro-6-methoxy-
CBNumber
CB9351794
Molecular Formula
C5H5ClN2O
Formula Weight
144.56
MOL File
33332-30-8.mol
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2-CHLORO-6-METHOXYPYRAZINE Property

Boiling point:
183.3±35.0 °C(Predicted)
Density 
1.292±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
solid
pka
-1.79±0.10(Predicted)
Appearance
Off-white to light yellow Solid-liquid mixture
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Safety

Risk Statements 
41
Safety Statements 
26-39
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SYX00288
Product name
2-Chloro-6-methoxypyrazine
Packaging
1g
Price
$107
Updated
2025/07/31
TRC
Product number
C381675
Product name
2-Chloro-6-methoxypyrazine
Packaging
100mg
Price
$75
Updated
2021/12/16
Matrix Scientific
Product number
069525
Product name
2-Chloro-6-methoxypyrazine
Purity
98%
Packaging
1g
Price
$38
Updated
2021/12/16
Apolloscientific
Product number
OR961527
Product name
2-Chloro-6-methoxypyrazine
Purity
98%
Packaging
1g
Price
$75
Updated
2021/12/16
AK Scientific
Product number
W5506
Product name
2-Chloro-6-methoxypyrazine
Packaging
1g
Price
$83
Updated
2021/12/16
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2-CHLORO-6-METHOXYPYRAZINE Chemical Properties,Usage,Production

Synthesis

67-56-1

4774-14-5

33332-30-8

1. Methanol (MeOH, 0.27 mL, 6.7 mmol) was dissolved in 15 mL of tetrahydrofuran (THF). 2. Add sodium hydride (NaH, 60 wt% mineral oil dispersion, 0.32 g, 8.0 mmol) to the above solution and stir for 30 minutes at room temperature. 3. 2,6-dichloropyrazine (1.0 g, 6.7 mmol) dissolved in 20 mL of THF was added slowly and stirring was continued for 16 hours at room temperature. 4. Upon completion of the reaction, the reaction was quenched by the addition of aqueous ammonium chloride and the reaction mixture was extracted with ether (Et2O). 5. The organic layers were combined, dried over anhydrous magnesium sulfate, filtered and purified by column chromatography to afford the target product, 2-chloro-6-methoxypiperazine (0.71 g, 73% yield). 6. The structure of the product was confirmed by 1H-NMR (CDCl3): δ 8.14 (1H, s), 8.13 (1H, s), 3.99 (3H, s).

References

[1] Patent: EP3239143, 2017, A2. Location in patent: Paragraph 0467

2-CHLORO-6-METHOXYPYRAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-CHLORO-6-METHOXYPYRAZINE Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
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jkinfo@jkchemical.com
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China
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96815
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76
Pure Chemistry Scientific Inc.
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001-857-928-2050 or 1-888-588-9418
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001-617-206-9595
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sales@chemreagents.com
Country
United States
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10186
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Tetranov Biopharm
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13526569071
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sales@leadmedpharm.com
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China
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Accela ChemBio Co.,Ltd.
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021-50795510 4000665055
Fax
021-50795055
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sales@accelachem.com
Country
China
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11035
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Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
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42934
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Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
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China
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Shanghai Sunway Pharmaceutical Technology Co., Ltd
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18270980682
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021 51613951
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Kohn & Shawn Pharmatech Co.,Ltd
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+86-931-8506154
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sales@kyxpharma.com
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China
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Xi'an Manareco New Materials Co., Ltd.
Tel
029-68669089-8816
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+86-29-68669073
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China
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Chiba Pharmaceutical Science and technology Co, Ltd.
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0531-81313138 13066006660
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QQ: 3366077777
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chibapharm@foxmail.com
Country
China
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3992
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View Lastest Price from 2-CHLORO-6-METHOXYPYRAZINE manufacturers

Career Henan Chemical Co
Product
2-CHLORO-6-METHOXYPYRAZINE 33332-30-8
Price
US $6.68/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg-1000kg
Release date
2020-01-09