Amino-PEG10-alcohol
- Product Name
- Amino-PEG10-alcohol
- CAS No.
- 129449-09-8
- Chemical Name
- Amino-PEG10-alcohol
- Synonyms
- H2N-PEG10-OH;Amino-PEG10-OH;NH2-PEG10-alcohol;Amino-PEG10-alcohol;29-Amino-3,6,9,12,15,18,21,24,27-nonaoxanonacosan-1-ol;3,6,9,12,15,18,21,24,27-Nonaoxanonacosan-1-ol, 29-amino-;H2N-PEG10-OH/3,6,9,12,15,18,21,24,27-Nonaoxanonacosan-1-ol, 29-amino-
- CBNumber
- CB13062312
- Molecular Formula
- C20H43NO10
- Formula Weight
- 457.56
- MOL File
- 129449-09-8.mol
Amino-PEG10-alcohol Property
- Boiling point:
- 533.3±45.0 °C(Predicted)
- Density
- 1.096±0.06 g/cm3(Predicted)
- pka
- 14.36±0.10(Predicted)
Safety
- HS Code
- 2918999090
N-Bromosuccinimide Price
- Product number
- A619493
- Product name
- Amino-PEG10-alcohol
- Packaging
- 100mg
- Price
- $265
- Updated
- 2021/12/16
- Product number
- BIPG1051
- Product name
- Amino-PEG10-alcohol
- Packaging
- 250mg
- Price
- $334
- Updated
- 2021/12/16
- Product number
- BP-22590
- Product name
- Amino-PEG10-alcohol
- Purity
- 98%
- Packaging
- 500mg
- Price
- $360
- Updated
- 2021/12/16
- Product number
- BIPG1051
- Product name
- Amino-PEG10-alcohol
- Packaging
- 500mg
- Price
- $636
- Updated
- 2021/12/16
- Product number
- AS104169
- Product name
- H2N-PEG10-OH
- Purity
- 95+%
- Packaging
- 1g
- Price
- $673
- Updated
- 2021/12/16
Amino-PEG10-alcohol Chemical Properties,Usage,Production
Description
Amino-PEG10-alcohol is a highly water soluble PEG reagent. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
Biological Activity
Amino-PEG10-OH is a non-cleavable 10-unit PEG-ADC linker for antibody drug-drug (ADC) synthesis. It is also a PEG-based PROTAC linker that can be used for PROTAC synthesis.
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
target
Non-cleavable < span> | PEGs
|
Amino-PEG10-alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Amino-PEG10-alcohol manufacturers
- Product
- Amino-PEG10-alcohol 129449-09-8
- Price
- US $0.00/mg
- Min. Order
- 250mg
- Purity
- >98.00%
- Supply Ability
- 250mg
- Release date
- 2024-03-22
- Product
- Amino-PEG10-alcohol 129449-09-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 97%-99.9%
- Supply Ability
- 100kg
- Release date
- 2019-12-21