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Biotin-PEG12-Acid

Product Name
Biotin-PEG12-Acid
CAS No.
1621423-14-0
Chemical Name
Biotin-PEG12-Acid
Synonyms
Biotin-PEG12-Acid;(+)-Biotin-PEG12-acid;(+)-Biotin-PEG12-CH2CH2COOH;ALPHA-BIOTIN-OMEGA-(PROPIONIC ACID)-DODECAE(ETHYLENE GLYCOL);4,7,10,13,16,19,22,25,28,31,34,37-Dodecaoxa-40-azapentatetracontanoic acid, 45-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-41-oxo-;Biotin-PEG12-CH2CH2COOH/4,7,10,13,16,19,22,25,28,31,34,37-Dodecaoxa-40-azapentatetracontanoic acid, 45-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-41-oxo-
CBNumber
CB13062387
Molecular Formula
C37H69N3O16S
Formula Weight
844.02
MOL File
1621423-14-0.mol
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Biotin-PEG12-Acid Property

Boiling point:
932.7±65.0 °C(Predicted)
Density 
1.171±0.06 g/cm3(Predicted)
pka
4.28±0.10(Predicted)
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Safety

HS Code 
2942000090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-21620
Product name
Biotin-PEG12-acid
Purity
98%
Packaging
100mg
Price
$295
Updated
2021/12/16
BroadPharm
Product number
BP-21620
Product name
Biotin-PEG12-acid
Purity
98%
Packaging
500mg
Price
$780
Updated
2021/12/16
purepeg
Product number
246812
Product name
(+)-Biotin-PEG12-CH2CH2COOH
Purity
min.97%
Packaging
50mg
Price
$200
Updated
2021/12/16
Acrotein
Product number
B-1363
Product name
Biotin-PEG12-CH2CH2COOH
Purity
97%
Packaging
0.25g
Price
$440
Updated
2021/12/16
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Biotin-PEG12-Acid Chemical Properties,Usage,Production

Description

Biotin-PEG12-acid is a biotin PEG linker containing a carboxylic acid group, it is reactive with amine moiety. The hydrophilic PEG spacer arm imparts water solubility that is transferred to the biotinylated molecule.

Uses

Biotin-PEG12-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. DOI:10.1038/nchembio.2329

Biotin-PEG12-Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Biotin-PEG12-Acid Suppliers

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View Lastest Price from Biotin-PEG12-Acid manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Biotin-PEG12-COOH 1621423-14-0
Price
US $0.00/g
Min. Order
1g
Purity
>95.00%
Supply Ability
1g
Release date
2024-03-30
Career Henan Chemical Co
Product
Biotin-PEG12-Acid 1621423-14-0
Price
US $1.00/KG
Min. Order
1KG
Purity
97%-99.9%
Supply Ability
100kg
Release date
2019-12-21

1621423-14-0, Biotin-PEG12-AcidRelated Search:

(+)-Biotin-PEG12-CH2CH2COONHS Ester Biotin-PEG12-hydrazide (+)-Biotin-PEG12-NH-Mal 1H-Thieno[3,4-d]imidazole-4-pentanamide,N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-,(3aS,4S,6aR)- Biotin-PEG4-N3 Biotin-PEG6-Mal Biotin-PEG3-Mal 15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester N-Biotinyl-N'-(3-maleimidopropionyl)-3,6-dioxaoctane-1,8-diamine [3aS,4S,6aR,(+)]-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid 5-oxide Biotin-PEG3-N3 Biotin-PEG2-Acid 9-biotinlaMino-4,7-dioxanonanoic acid N-hydroxysucciniMidyl ester 21-[D(+)-Biotinylamino]-4,7,10,13,16,19-hexaoxaheneicosanoic acid Biotin-PEG7-Azide Biotin-PEG5-azide 15-[D(+)-BIOTINYLAMINO]-4,7,10,13-TETRAOXAPENTADECANOIC ACID Biotin-PEG3-propionic acid

  • Biotin-PEG12-Acid
  • (+)-Biotin-PEG12-CH2CH2COOH
  • 4,7,10,13,16,19,22,25,28,31,34,37-Dodecaoxa-40-azapentatetracontanoic acid, 45-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-41-oxo-
  • (+)-Biotin-PEG12-acid
  • Biotin-PEG12-CH2CH2COOH/4,7,10,13,16,19,22,25,28,31,34,37-Dodecaoxa-40-azapentatetracontanoic acid, 45-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-41-oxo-
  • ALPHA-BIOTIN-OMEGA-(PROPIONIC ACID)-DODECAE(ETHYLENE GLYCOL)
  • 1621423-14-0