N-Biotinyl-N'-(3-maleimidopropionyl)-3,6-dioxaoctane-1,8-diamine

Product Name: N-Biotinyl-N'-(3-maleimidopropionyl)-3,6-dioxaoctane-1,8-diamine
CAS No.: 305372-39-8
Chemical Name: N-Biotinyl-N'-(3-maleimidopropionyl)-3,6-dioxaoctane-1,8-diamine
Synonyms: mPE12-OH;propanamido);Biotin-PEG2-Mal;Biotin Impurity 70;Biotin-PEG2-amido-Mal;Amido-Mal-PEG2-Biotin;(+)-Biotin-PEG2-NH-Mal;(+)-Biotin-PEG2-Maleimide;(+)-BIOTIN-(PEO)3-MALEIMIDE(I);Biotin PEG2 maleimide *CAS 305372-39-8*
CBNumber: CB72470738
Molecular Formula: C23H35N5O7S
Formula Weight: 525.62
MOL File: 305372-39-8.mol

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N-Biotinyl-N'-(3-maleimidopropionyl)-3,6-dioxaoctane-1,8-diamine Property

Boiling point:: 897.0±65.0 °C(Predicted)
Density: 1.271±0.06 g/cm3(Predicted)
storage temp.: <0°C
solubility: Soluble in DMSO, DCM, DMF
pka: 13.90±0.40(Predicted)
form: powder to crystal
color: White to Orange to Green
SMILES: O=C(N1CCC(NCCOCCOCCNC(CCCC[C@H]2[C@@]3([C@]([H])(CS2)NC(N3)=O)[H])=O)=O)C=CC1=O

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Safety

HS Code: 2930.90.9190

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B3174
Product name: N-Biotinyl-N'-(3-maleimidopropionyl)-3,6-dioxaoctane-1,8-diamine
Purity: >90.0%(HPLC)
Packaging: 50mg
Price: $198
Updated: 2026/04/30

Cayman Chemical

Product number: 44569
Product name: Biotin-PEG2-Maleimide
Purity: ≥95%
Packaging: 50mg
Price: $28
Updated: 2026/04/30

Cayman Chemical

Product number: 44569
Product name: Biotin-PEG2-Maleimide
Purity: ≥95%
Packaging: 100mg
Price: $53
Updated: 2026/04/30

Cayman Chemical

Product number: 44569
Product name: Biotin-PEG2-Maleimide
Purity: ≥95%
Packaging: 250mg
Price: $98
Updated: 2026/04/30

Cayman Chemical

Product number: 44569
Product name: Biotin-PEG2-Maleimide
Purity: ≥95%
Packaging: 500mg
Price: $182
Updated: 2026/04/30

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N-Biotinyl-N'-(3-maleimidopropionyl)-3,6-dioxaoctane-1,8-diamine Chemical Properties,Usage,Production

Description

Biotin-PEG2-Mal is a biotin maleimide linker that reacts specifically with sulfhydryl groups (at pH 6.5-7.5) to form a stable, irreversible thioether linkage.

Uses

Biotin-PEG2-Mal is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.

IC 50

PEGs

N-Biotinyl-N'-(3-maleimidopropionyl)-3,6-dioxaoctane-1,8-diamine Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Biotinyl-N'-(3-maleimidopropionyl)-3,6-dioxaoctane-1,8-diamine Suppliers

Americas 1 CHINA 88 Europe 1 India 2 Japan 1 United Kingdom 2 United States 10 Global 105

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
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Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
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TCI (Shanghai) Development Co., Ltd.

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Energy Chemical

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ChemPep, Inc.

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BOC Sciences

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TOKYO CHEMICAL INDUSTRY CO., LTD.

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View Lastest Price from N-Biotinyl-N'-(3-maleimidopropionyl)-3,6-dioxaoctane-1,8-diamine manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.

Product: Biotin-PEG2-amido-MAL 305372-39-8
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
Release date: 2026-02-06

Xian confluore Biological Technology Co., Ltd.

Product: Biotin-PEG2-amido-Mal 305372-39-8
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-30

305372-39-8, N-Biotinyl-N'-(3-maleimidopropionyl)-3,6-dioxaoctane-1,8-diamineRelated Search:

Biotin-PEG5-azide N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE ATBTA-EU3+ biotinylamidoethylacetamide SULPHOSUCCINIMIDYL-6-(BIOTINAMIDO)HEXANOATE (+)-BIOTIN-EPSILON-AMINOCAPROIC ACID Succinimidyl 6-(biotinamido)hexanoate D-DESTHIOBIOTIN BIOTIN-4-FLUORESCEIN UV-Tracer Biotin NHS Ester Biotin-PEG5-Amine N-BIOTINYL-3,6-DIOXAOCTANE-1,8-DIAMINE 1H-Thieno[3,4-d]imidazole-4-pentanamide,N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-,(3aS,4S,6aR)- Biotin-PEG4-N3 Biotin-PEG<sub>4</sub>-Azide Biotin-PEG3-N3 Biotin-PEG2-Hydrazide 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-N-[2-(2-hydroxyethoxy)ethyl]-2-oxo-, (3aS,4S,6aR)-

N-Biotinyl-N'-(3-maleimidopropionyl)-3,6-dioxaoctane-1,8-diamine

1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[2-[2-[2-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)-

Biotin-PEG2-Mal

N-(2-(2-(2-(3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)

propanamido)

N-(2-(2-(2-(3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide

(+)-Biotin-PEG2-NH-Mal

Biotin PEG2 maleimide *CAS 305372-39-8*

(+)-BIOTIN-(PEO)3-MALEIMIDE(I)

mPE12-OH

N-Biotinyl-N'-(3-maleimidopropionyl)-3,6-dioxaoctane-1,8-diamine &gt

Biotin Impurity 70

N-[2-[2-[2-[(3-Maleimidopropionyl)amino]ethoxy]ethoxy]ethyl]biotinamide

(+)-Biotin-PEG2-Maleimide

Biotin-PEG2-amido-Mal

5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]-N-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethyl]pentanamide

Amido-Mal-PEG2-Biotin

305372-39-8

peg

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