D-DESTHIOBIOTIN

Product Name: D-DESTHIOBIOTIN
CAS No.: 533-48-2
Chemical Name: D-DESTHIOBIOTIN
Synonyms: DESTHIOBIOTIN;Dethiobiotin;6-((4R,5S)-5-Methyl-2-oxoiMidazolidin-4-yl)hexanoic acid;ethiobiotin;CAS_533-48-2;D-Dethiobiotin;D-DESTHIOBIOTIN;DL-DESTHIOBIOTIN;Desulfurized biotin;D-desulfurized biotin
CBNumber: CB2259792
Molecular Formula: C10H18N2O3
Formula Weight: 214.26
MOL File: 533-48-2.mol

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D-DESTHIOBIOTIN Property

Melting point:: 156-158°
alpha: D21 +10.7° (c = 2)
Boiling point:: 354.4°C (rough estimate)
Density: 1.1404 (rough estimate)
refractive index: 1.4550 (estimate)
storage temp.: 2-8°C
solubility: Aqueous Base (Slightly), DMSO (Slightly)
form: Solid
pka: 4.77±0.10(Predicted)
color: White to Off-White
InChI: InChI=1S/C10H18N2O3/c1-7-8(12-10(15)11-7)5-3-2-4-6-9(13)14/h7-8H,2-6H2,1H3,(H,13,14)(H2,11,12,15)/t7-,8+/m0/s1
InChIKey: AUTOLBMXDDTRRT-UHFFFAOYSA-N
SMILES: C1(=O)N[C@@H](C)[C@@H](CCCCCC(O)=O)N1

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Safety

WGK Germany: 3
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D1411
Product name: d-Desthiobiotin
Purity: ≥98% (TLC)
Packaging: 500mg
Price: $200
Updated: 2025/07/31

Sigma-Aldrich

Product number: D1411
Product name: d-Desthiobiotin
Purity: ≥98% (TLC)
Packaging: 1g
Price: $341
Updated: 2025/07/31

Sigma-Aldrich

Product number: 71610-M
Product name: D-Desthiobiotin
Packaging: 1g
Price: $477
Updated: 2025/07/31

Cayman Chemical

Product number: 30418
Product name: D-Desthiobiotin
Packaging: 100mg
Price: $56
Updated: 2024/03/01

Cayman Chemical

Product number: 30418
Product name: D-Desthiobiotin
Packaging: 250mg
Price: $118
Updated: 2024/03/01

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D-DESTHIOBIOTIN Chemical Properties,Usage,Production

Uses

D-Desthiobiotin is an analogue of Biotin (B389040) that binds less tightly to biotin-binding proteins such as Avidin and is easily displaced by Biotin.

Definition

ChEBI: (4R,5S)-dethiobiotin is the (4R,5S)-isomer of dethiobiotin. It is a conjugate acid of a (4R,5S)-dethiobiotin(1-). It is an enantiomer of a (4S,5R)-dethiobiotin.

Biological Activity

Desthiobiotin is a non-sulfur containing biotin derivative th at binds less strongly to biotin-binding proteins and is easily dislocated by biotin.

IC 50

Microbial Metabolite; Human Endogenous Metabolite

Purification Methods

Dissolve desthiobiotin in 0.5% Na2CO3, filter, acidify with HCl to Congo Red, concentrate to a small volume (2-3 mL) to give fine needles, filter it off and recrystallise it twice from H2O, m 157-158o. It also crystallises from 95% EtOH. The methyl ester crystallises from MeOH and sublimes at 100o/high vacuum, m 69-70o, [] D +2.6o (c 2, CHCl3). [Melville et al. Science 98 497 1943, J Am Chem Soc 66 1422 1944, Beilstein 25 III/IV 1543.]

D-DESTHIOBIOTIN Preparation Products And Raw materials

Raw materials

Preparation Products

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D-DESTHIOBIOTIN Suppliers

China 134 India 2 Switzerland 1 United Kingdom 2 United States 12 Global 151

Shanghai TenSus Biotechnology Co., Ltd.

Tel: 021-50895067 18616507272
Fax: 021-50895067
Email: tensus@163.com
Country: China
ProdList: 8073
Advantage: 58

Hangzhou Taorui Biotechnology Co., Ltd

Tel: 4000-360-990 15268198094
Email: sales@torreybio.com
Country: China
ProdList: 3873
Advantage: 58

Jiangsu aikang biomedical research and development co., LTD

Tel: 025-58859352 13155353615
Email: qzhang@aikonchem.com
Country: China
ProdList: 15525
Advantage: 58

Hefei fuya biotechnology co. LTD

Tel: 18096409024
Email: sales02@foreversyn.com
Country: China
ProdList: 1938
Advantage: 58

Shanghai Harmony Bio-Pharmaceutical Technology Co., Ltd.

Tel: 021-18019086215 18019086215
Email: ljf_navigator@163.com
Country: China
ProdList: 827
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: 18143011203
Email: ET-market@chemextension.com
Country: China
ProdList: 32275
Advantage: 58

JiangSu Star Science Co.,Ltd

Tel: 400-605-7200 15335295587
Email: 3941881028@qq.com
Country: China
ProdList: 3760
Advantage: 58

Puyang Borui Technology Development Co., Ltd

Tel: 15203933070
Email: 450281857@qq.com
Country: China
ProdList: 116
Advantage: 58

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

Beijing HwrkChemical Technology Co., Ltd

Tel: 010-89508211 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9401
Advantage: 55

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View Lastest Price from D-DESTHIOBIOTIN manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Dethiobiotin 533-48-2
Price: US $0.00/g
Min. Order: 5g
Purity: >95.00%
Supply Ability: 5g
Release date: 2024-03-30

Dideu Industries Group Limited

Product: D-DESTHIOBIOTIN 533-48-2
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-07-30

533-48-2, D-DESTHIOBIOTINRelated Search:

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5-METHYL-2-OXO-4-IMIDAZOLINE-CAPROIC ACID

DL-DESTHIOBIOTIN

CAS_533-48-2

D-DESTHIOBIOTIN

DESTHIOBIOTIN

(4R-cis)-5-methyl-2-oxoimidazolidine-4-hexanoic acid

6-(5-methyl-2-oxo-imidazolidin-4-yl)hexanoic acid

Dethiobiotin

5-Methyl-2-oxo-4-imidazolidinehexanoic acid

(4R)-2-Oxo-5α-methylimidazolidine-4α-hexanoic acid

[4R,5S,(+)]-5-Methyl-2-oxo-4-imidazolidinehexanoic acid

6-((4R,5S)-5-Methyl-2-oxoiMidazolidin-4-yl)hexanoic acid

4-Imidazolidinehexanoic acid, 5-methyl-2-oxo-, (4R,5S)-

d-Desthiobiotin >=98% (TLC)

Desulfurized biotin

D-DESTHIOBIOTIN USP/EP/BP

D-desulfurized biotin

ethiobiotin

D-Dethiobiotin

D-Desthiobiotin, 10 mM in DMSO

<i>d</i>-Desthiobiotin

533-48-2