1951424-89-7
- Product Name
- 1951424-89-7
- CAS No.
- 1951424-89-7
- Chemical Name
- 1951424-89-7
- Synonyms
- CAS_1951424-89-7;Desthiobiotin-PEG4-propargyl;Desthiobiotin Alkyne (CCT-1109);4-Imidazolidinehexanamide, 5-methyl-2-oxo-N-3,6,9,12-tetraoxapentadec-14-yn-1-yl-, (4R,5S)-;6-((4R,5S)-5-Methyl-2-oxoimidazolidin-4-yl)-N-(3,6,9,12-tetraoxapentadec-14-yn-1-yl)hexanamide
- CBNumber
- CB63369414
- Molecular Formula
- C21H37N3O6
- Formula Weight
- 427.54
- MOL File
- 1951424-89-7.mol
1951424-89-7 Property
- storage temp.
- Storage temp. 2-8°C
- form
- Viscous Liquid
- color
- Light yellow to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 35172
- Product name
- Desthiobiotinalkyne,95%(HPLC)
- Purity
- 95%(HPLC)
- Packaging
- 5MG
- Price
- $179.2
- Updated
- 2021/12/16
- Product number
- 35172
- Product name
- Desthiobiotinalkyne,95%(HPLC)
- Purity
- 95%(HPLC)
- Packaging
- 25MG
- Price
- $352.8
- Updated
- 2021/12/16
- Product number
- 35172
- Product name
- Desthiobiotinalkyne,95%(HPLC)
- Purity
- 95%(HPLC)
- Packaging
- 100MG
- Price
- $1400
- Updated
- 2021/12/16
1951424-89-7 Chemical Properties,Usage,Production
Uses
Desthiobiotin-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Desthiobiotin-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
1951424-89-7 Preparation Products And Raw materials
Raw materials
Preparation Products
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