ChemicalBook > CAS DataBase List > 1951424-89-7

1951424-89-7

Product Name
1951424-89-7
CAS No.
1951424-89-7
Chemical Name
1951424-89-7
Synonyms
CAS_1951424-89-7;Desthiobiotin-PEG4-propargyl;Desthiobiotin Alkyne (CCT-1109);4-Imidazolidinehexanamide, 5-methyl-2-oxo-N-3,6,9,12-tetraoxapentadec-14-yn-1-yl-, (4R,5S)-;6-((4R,5S)-5-Methyl-2-oxoimidazolidin-4-yl)-N-(3,6,9,12-tetraoxapentadec-14-yn-1-yl)hexanamide
CBNumber
CB63369414
Molecular Formula
C21H37N3O6
Formula Weight
427.54
MOL File
1951424-89-7.mol
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1951424-89-7 Property

storage temp. 
Storage temp. 2-8°C
form 
Viscous Liquid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Chem-Impex
Product number
35172
Product name
Desthiobiotinalkyne,95%(HPLC)
Purity
95%(HPLC)
Packaging
5MG
Price
$179.2
Updated
2021/12/16
Chem-Impex
Product number
35172
Product name
Desthiobiotinalkyne,95%(HPLC)
Purity
95%(HPLC)
Packaging
25MG
Price
$352.8
Updated
2021/12/16
Chem-Impex
Product number
35172
Product name
Desthiobiotinalkyne,95%(HPLC)
Purity
95%(HPLC)
Packaging
100MG
Price
$1400
Updated
2021/12/16
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1951424-89-7 Chemical Properties,Usage,Production

Uses

Desthiobiotin-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Desthiobiotin-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

1951424-89-7 Preparation Products And Raw materials

Raw materials

Preparation Products

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1951424-89-7 Suppliers

Bide Pharmatech Ltd.
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1951424-89-7, 1951424-89-7Related Search:


  • CAS_1951424-89-7
  • Desthiobiotin-PEG4-propargyl
  • 4-Imidazolidinehexanamide, 5-methyl-2-oxo-N-3,6,9,12-tetraoxapentadec-14-yn-1-yl-, (4R,5S)-
  • Desthiobiotin Alkyne (CCT-1109)
  • 6-((4R,5S)-5-Methyl-2-oxoimidazolidin-4-yl)-N-(3,6,9,12-tetraoxapentadec-14-yn-1-yl)hexanamide
  • 1951424-89-7