Mes-PEG2-acid t-butyl ester

Product Name: Mes-PEG2-acid t-butyl ester
CAS No.: 1312309-62-8
Chemical Name: Mes-PEG2-acid t-butyl ester
Synonyms: Ms-PEG2-C2-Boc;CAS_1312309-62-8;Ms-PEG2-t-butyl ester;Mes-PEG2-acid t-butyl ester;4,7,10-Trioxa-11-thiadodecanoic acid, 1,1-dimethylethyl ester, 11,11-dioxide
CBNumber: CB13062549
Molecular Formula: C12H24O7S
Formula Weight: 312.38
MOL File: 1312309-62-8.mol

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Mes-PEG2-acid t-butyl ester Property

Boiling point:: 429.2±30.0 °C(Predicted)
Density: 1.155±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
solubility: Soluble in DMSO, DCM, DMF
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: M755305
Product name: MS-PEG3-t-butylEster
Packaging: 10mg
Price: $45
Updated: 2021/12/16

TRC

Product number: M755305
Product name: MS-PEG3-t-butylEster
Packaging: 100mg
Price: $220
Updated: 2021/12/16

BroadPharm

Product number: BP-20557
Product name: Ms-PEG2-t-butylester
Purity: 98%
Packaging: 500mg
Price: $330
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1520
Product name: Mes-PEG2-acid t-butyl ester
Packaging: 500mg
Price: $681
Updated: 2021/12/16

BroadPharm

Product number: BP-20557
Product name: Ms-PEG2-t-butylester
Purity: 98%
Packaging: 5G
Price: $1440
Updated: 2021/12/16

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Mes-PEG2-acid t-butyl ester Chemical Properties,Usage,Production

Description

Ms-PEG2-t-butyl ester is a PEG linker containing a mesyl group and a t-butyl protecting group. The mesyl group is a good leaving group for nucleophilic substitution reactions. The t-butyl is an acid labile protecting group. Upon removal, the carboxylic acid can react with primary amines. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.

Uses

Ms-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Mes-PEG2-acid t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Mes-PEG2-acid t-butyl ester Suppliers

China 25 India 1 United Kingdom 1 United States 4 Global 31

Borenpharm Co., Ltd

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1312309-62-8, Mes-PEG2-acid t-butyl esterRelated Search:

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Mes-PEG2-acid t-butyl ester

Ms-PEG2-t-butyl ester

CAS_1312309-62-8

Ms-PEG2-C2-Boc

4,7,10-Trioxa-11-thiadodecanoic acid, 1,1-dimethylethyl ester, 11,11-dioxide

1312309-62-8

C12H24O7S