ChemicalBook > CAS DataBase List > Mes-PEG2-acid t-butyl ester
Mes-PEG2-acid t-butyl ester
- Product Name
- Mes-PEG2-acid t-butyl ester
- CAS No.
- 1312309-62-8
- Chemical Name
- Mes-PEG2-acid t-butyl ester
- Synonyms
- Ms-PEG2-C2-Boc;CAS_1312309-62-8;Ms-PEG2-t-butyl ester;Mes-PEG2-acid t-butyl ester;4,7,10-Trioxa-11-thiadodecanoic acid, 1,1-dimethylethyl ester, 11,11-dioxide
- CBNumber
- CB13062549
- Molecular Formula
- C12H24O7S
- Formula Weight
- 312.38
- MOL File
- 1312309-62-8.mol
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Mes-PEG2-acid t-butyl ester Property
- Boiling point:
- 429.2±30.0 °C(Predicted)
- Density
- 1.155±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in DMSO, DCM, DMF
- form
- Liquid
- color
- Colorless to light yellow
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N-Bromosuccinimide Price
TRC
- Product number
- M755305
- Product name
- MS-PEG3-t-butylEster
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
TRC
- Product number
- M755305
- Product name
- MS-PEG3-t-butylEster
- Packaging
- 100mg
- Price
- $220
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-20557
- Product name
- Ms-PEG2-t-butylester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $330
- Updated
- 2021/12/16
Apolloscientific
- Product number
- BIPG1520
- Product name
- Mes-PEG2-acid t-butyl ester
- Packaging
- 500mg
- Price
- $681
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-20557
- Product name
- Ms-PEG2-t-butylester
- Purity
- 98%
- Packaging
- 5G
- Price
- $1440
- Updated
- 2021/12/16
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Mes-PEG2-acid t-butyl ester Chemical Properties,Usage,Production
Description
Ms-PEG2-t-butyl ester is a PEG linker containing a mesyl group and a t-butyl protecting group. The mesyl group is a good leaving group for nucleophilic substitution reactions. The t-butyl is an acid labile protecting group. Upon removal, the carboxylic acid can react with primary amines. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.
Uses
Ms-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Mes-PEG2-acid t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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Mes-PEG2-acid t-butyl ester Suppliers
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