ChemicalBook > CAS DataBase List > Mes-PEG5- THP
Mes-PEG5- THP
- Product Name
- Mes-PEG5- THP
- CAS No.
- 145927-73-7
- Chemical Name
- Mes-PEG5- THP
- Synonyms
- MS-PEG4-THP;Mes-PEG4- THP;Mes-PEG5- THP;CAS_145927-73-7;MSPEG4THP,MS-PEG-4-THP,PROTAC Linkers,inhibit,MS PEG4 THP,Inhibitor;2-(2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethoxy)ethyl methanesulfonate;Ethanol, 2-[2-[2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]ethoxy]ethoxy]-, 1-methanesulfonate
- CBNumber
- CB23048724
- Molecular Formula
- C14H28O8S
- Formula Weight
- 356.43
- MOL File
- 145927-73-7.mol
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Mes-PEG5- THP Chemical Properties,Usage,Production
Biological Activity
MS-PEG4-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Mes-PEG5- THP Preparation Products And Raw materials
Raw materials
Preparation Products
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