DCEBIO

Product Name: DCEBIO
CAS No.: 60563-36-2
Chemical Name: DCEBIO
Synonyms: DCEBIO;DCEBIO, 10 mM in DMSO;Potassium Channel,KcsA,DCEBIO,inhibit,Inhibitor;5,6-DICHLORO-1-ETHYL-1H-BENZO[D]IMIDAZOL-2(3H)-ONE;5,6-DICHLORO-1-ETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE;5,6-DICHLORO-1-ETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOLE-2-ONE;2H-Benzimidazol-2-one, 5,6-dichloro-1-ethyl-1,3-dihydro-;5,6-dichloro-1-ethyl-1,3-dihydro-2H-benzo[d]imidazol-2-one
CBNumber: CB1308237
Molecular Formula: C9H8Cl2N2O
Formula Weight: 231.08
MOL File: 60563-36-2.mol

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DCEBIO Property

Melting point:: 205-207 °C(Solv: ethyl acetate (141-78-6))
Density: 1.412±0.06 g/cm3(Predicted)
storage temp.: Store at RT
solubility: DMSO: >10mg/mL
form: solid
pka: 10.28±0.30(Predicted)
color: off-white
InChI: 1S/C9H8Cl2N2O/c1-2-13-8-4-6(11)5(10)3-7(8)12-9(13)14/h3-4H,2H2,1H3,(H,12,14)
InChIKey: LKHRMULASXZCLG-UHFFFAOYSA-N
SMILES: CCN1C(=O)Nc2cc(Cl)c(Cl)cc12

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D9190
Product name: DCEBIO
Purity: ≥98% (HPLC), solid
Packaging: 5mg
Price: $206
Updated: 2025/07/31

Sigma-Aldrich

Product number: D9190
Product name: DCEBIO
Purity: ≥98% (HPLC), solid
Packaging: 25mg
Price: $770
Updated: 2023/06/20

Cayman Chemical

Product number: 29426
Product name: DCEBIO
Packaging: 5mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 29426
Product name: DCEBIO
Packaging: 10mg
Price: $116
Updated: 2024/03/01

Cayman Chemical

Product number: 29426
Product name: DCEBIO
Packaging: 25mg
Price: $268
Updated: 2024/03/01

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DCEBIO Chemical Properties,Usage,Production

Description

DCEBIO, a derivative of 1-EBIO, is an extremely potent activator of Cl- secretion in T84 colonic cells. DCEBIO stimulates Cl- secretion via the activation of hIK1 K+ channels and the activation of an apical membrane Cl- conductance.

Uses

DCEBIO is a small Ca2+sensitive K+ channel (SKCa) agonist. It also stimulate nitric oxide (NO) synthesis and vasodilation in resistance arteries.

Definition

ChEBI: DCEBIO is a dichlorobenzene.

Biological Activity

Stimulates Cl - secretion via activation of hIK1 K + channels and the activation of an apical Cl - conductance. More potent than its analog 1-EBIO (1-Ethyl-2-benzimidazolinone ).

storage

Store at RT

DCEBIO Preparation Products And Raw materials

Raw materials

Preparation Products

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DCEBIO Suppliers

Canada 1 CHINA 53 Germany 2 India 2 Switzerland 1 United Kingdom 1 United States 8 USA 1 Global 69

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

Shanghai Ennopharm Co., Ltd.

Tel: +86 (21) 6435-5022
Country: China
ProdList: 4267
Advantage: 65

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9895
Advantage: 58

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9519
Advantage: 58

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

Quality Control Solutions Ltd.

Tel: 66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18364
Advantage: 56

Shanghai PharmOrgsyn Technology Co., LTD.

Tel: 021-+86-021-38228826 13916602830;
Fax: sales@pharmorgsyn.com
Email: sales@pharmorgsyn.cn
Country: China
ProdList: 232
Advantage: 58

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

60563-36-2, DCEBIORelated Search:

3-Pentanone Ethylhexyl Triazone 2-Methoxyethyl chloride Tris(2-chloroethyl) phosphate DCEBIO

DCEBIO

5,6-DICHLORO-1-ETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE

5,6-DICHLORO-1-ETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOLE-2-ONE

5,6-DICHLORO-1-ETHYL-1H-BENZO[D]IMIDAZOL-2(3H)-ONE

2H-Benzimidazol-2-one, 5,6-dichloro-1-ethyl-1,3-dihydro-

Potassium Channel,KcsA,DCEBIO,inhibit,Inhibitor

DCEBIO, 10 mM in DMSO

5,6-dichloro-1-ethyl-1,3-dihydro-2H-benzo[d]imidazol-2-one

60563-36-2

C9H8N2OCl2

Chloride Channel Modulators

Voltage-gated Ion Channels

Monovalent Ion Channels

Ion Channels

Cell Biology

Cell Signaling and Neuroscience

BioChemical

Potassium channel