DCEBIO

Product Name: DCEBIO
CAS No.: 60563-36-2
Chemical Name: DCEBIO
Synonyms: DCEBIO;Potassium Channel,KcsA,DCEBIO,inhibit,Inhibitor;5,6-DICHLORO-1-ETHYL-1H-BENZO[D]IMIDAZOL-2(3H)-ONE;5,6-DICHLORO-1-ETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE;5,6-DICHLORO-1-ETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOLE-2-ONE;2H-Benzimidazol-2-one, 5,6-dichloro-1-ethyl-1,3-dihydro-
CBNumber: CB1308237
Molecular Formula: C9H8Cl2N2O
Formula Weight: 231.08
MOL File: 60563-36-2.mol

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DCEBIO Property

Melting point:: 205-207 °C(Solv: ethyl acetate (141-78-6))
Density: 1.412±0.06 g/cm3(Predicted)
storage temp.: Store at RT
solubility: DMSO: >10mg/mL
form: solid
pka: 10.28±0.30(Predicted)
color: off-white

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D9190
Product name: DCEBIO
Purity: ≥98% (HPLC), solid
Packaging: 5mg
Price: $200
Updated: 2024/03/01

Sigma-Aldrich

Product number: D9190
Product name: DCEBIO
Purity: ≥98% (HPLC), solid
Packaging: 25mg
Price: $770
Updated: 2023/06/20

Cayman Chemical

Product number: 29426
Product name: DCEBIO
Packaging: 5mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 29426
Product name: DCEBIO
Packaging: 10mg
Price: $116
Updated: 2024/03/01

Cayman Chemical

Product number: 29426
Product name: DCEBIO
Packaging: 25mg
Price: $268
Updated: 2024/03/01

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DCEBIO Chemical Properties,Usage,Production

Description

DCEBIO, a derivative of 1-EBIO, is an extremely potent activator of Cl- secretion in T84 colonic cells. DCEBIO stimulates Cl- secretion via the activation of hIK1 K+ channels and the activation of an apical membrane Cl- conductance.

Uses

DCEBIO is a small Ca2+sensitive K+ channel (SKCa) agonist. It also stimulate nitric oxide (NO) synthesis and vasodilation in resistance arteries.

Definition

ChEBI: DCEBIO is a dichlorobenzene.

Biological Activity

Stimulates Cl - secretion via activation of hIK1 K + channels and the activation of an apical Cl - conductance. More potent than its analog 1-EBIO (1-Ethyl-2-benzimidazolinone ).

storage

Store at RT

DCEBIO Preparation Products And Raw materials

Raw materials

Preparation Products

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DCEBIO Suppliers

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60563-36-2, DCEBIORelated Search:

3-Pentanone Ethylhexyl Triazone 2-Methoxyethyl chloride Tris(2-chloroethyl) phosphate DCEBIO

DCEBIO

5,6-DICHLORO-1-ETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE

5,6-DICHLORO-1-ETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOLE-2-ONE

5,6-DICHLORO-1-ETHYL-1H-BENZO[D]IMIDAZOL-2(3H)-ONE

2H-Benzimidazol-2-one, 5,6-dichloro-1-ethyl-1,3-dihydro-

Potassium Channel,KcsA,DCEBIO,inhibit,Inhibitor

60563-36-2

C9H8N2OCl2

Chloride Channel Modulators

Voltage-gated Ion Channels

Monovalent Ion Channels

Ion Channels

Cell Biology

Cell Signaling and Neuroscience

BioChemical

Potassium channel