Azadirachtin

ChemicalBook > CAS DataBase List > Azadirachtin

Product Name: Azadirachtin
CAS No.: 11141-17-6
Chemical Name: Azadirachtin
Synonyms: AZADIRACHTIN B;AZADIRACHTIN A;AZAD;Oikos;AZATIN;NEEMIX;Ecozin;Gronim;Suneem;KAYNEEM
CBNumber: CB1308833
Molecular Formula: C35H44O16
Formula Weight: 720.71
MOL File: 11141-17-6.mol

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Azadirachtin Property

Melting point:: 159°C
alpha: D -53° (c = 0.5 in CHCl3)
Boiling point:: 792.4±60.0 °C(Predicted)
Density: 1.51
storage temp.: −20°C
solubility: DMSO (Sparingly), Methanol (Slightly)
form: Solid
pka: 9.78±0.70(Predicted)
color: White to Pale Yellow
Merck: 13,896
Stability:: Light Sensitive
InChIKey: TWGPOIQWWGNBKW-POEZYEDVSA-N
LogP: 1.090
CAS DataBase Reference: 11141-17-6
EPA Substance Registry System: Azadirachtin A (11141-17-6)

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Safety

Risk Statements: 22
Safety Statements: 22-45
RIDADR: 3077
WGK Germany: 3
HazardClass: 9
PackingGroup: III
HS Code: 13021920
Hazardous Substances Data: 11141-17-6(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL89574
Product name: Azadirachtin
Purity: phyproof? Reference Substance
Packaging: 5MG
Price: $459
Updated: 2024/03/01

Sigma-Aldrich

Product number: A7430
Product name: Azadirachtin
Purity: ~95%
Packaging: 0.5mg
Price: $140
Updated: 2024/03/01

Cayman Chemical

Product number: 21893
Product name: Azadirachtin
Purity: ≥95%
Packaging: 1mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 21893
Product name: Azadirachtin
Purity: ≥95%
Packaging: 5mg
Price: $220
Updated: 2024/03/01

Cayman Chemical

Product number: 21893
Product name: Azadirachtin
Purity: ≥95%
Packaging: 10mg
Price: $330
Updated: 2024/03/01

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Azadirachtin Chemical Properties,Usage,Production

Description

Kernel extracts from the Indian neem tree (Azadirachta indica) have insecticidal and insect-repellent properties. The key active ingredient is azadirachtin, a nortriterpenoid that exhibits insect growth regulator effects but no adulticidal activity.

Chemical Properties

Off-white, yellowish powder or dark brown emulsifiable concentrate.

Uses

Azadiractin is extracted from the neem tree (Azadirachta indica). It is the principal active ingredient of extracts of neem. Neem extracts and pure azadirachtin are used to control whitefly, leaf miners and other pests including pear psylla.

Uses

Azadirachtin is a tetranortriterpinoid isolated from the seeds of the neem tree. Highly active insect feeding deterrent and growth regulator.It is used experimentally as insect control agent.

Definition

ChEBI: A member of the family of azadirachtins that is isolated from the neem tree (Azadirachta indica).

Agricultural Uses

Insecticides, Nematicide: Azadirachtin is an extract of fruit from the Neem tree, which is largely grown in India. It is used as a commercial insect growth regulator that controls the metamorphosis process as the insect passes from the larva stage to the pupa stage. The Neem tree also yields extracts from its bark, leaves and wood that are used in medicine and cosmetics.

Trade name

ALIGN®; AZATIN EC®; AZATIN®-XL PLUS; AZATROL EC®; AMAZIN® ECOZIN® EI- 783®; MARGOSAN-O®; NEEM®; NEEMAZAL®; ORNAZIN® SALANNIN®; SUPERNEEM®; TURPLEX®

Biochem/physiol Actions

Triterpenoid found in need tree seeds, azadiractin suppresses feeding by many insect species and disrupts growth of most insect and other arthropod species, while having very low mammalian toxicity. Promising as a natural pesticide.

Potential Exposure

Biological tetranortriterpinoid insecticide; insect growth regulator. A natural product extracted from seeds of the Neem tree (Azadirachta indica).

Metabolic pathway

The natural insecticide azadirachtin is most stable in mildly acidic solutions between pH 4 and 6 at room temperature and unstable in alkaline and strong acidic conditions. While azadirachtin is relatively stable to heating in the seeds or as a pure solid, it is rapidly destroyed or altered by heating in aqueous solution and methanol. In methanol at 90°C, it is quantitatively converted to 3-acetyl-1-tigloylazadirachtinin.

Shipping

UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.

Degradation

After 90 hours exposure to UV radiation, very little azadirachtin (l)its 3- acetyl derivative and 22,23-dihydroazadirachtin remained intact. However, these compounds retained biological activity, and at least 200 hours irradiation was necessary to reduce the biological activity of 1. It is suggested that the effect of ultraviolet radiation is confined to the tigloyl residue which is common to these three compounds and which may undergo cis-trans isomerisation, rearrangement, etc. without significant effect on the biological activity of the molecule, because reduction or removal of the tigloyl residue causes only limited reduction in biological activity of the parent (Barnby ef al., 1989).
Azadirachtin was hydrolysed readily in several buffers (pH 4.1-8.1) and natural waters (pH 6.2,7.3,8.0 and 8.1) at 35 °C and its disappearance followed pseudo-first-order kinetics (Szeto and Wan, 1996). Rates of disappearance of the parent were faster in basic than in acidic solution (DT₅₀ was 12 hours at pH 8 and 206 hours at pH 6) and the compound is not expected to be persistent in water.

Mode of action

Azadirachtin acts on insect gustatory receptors to inhibit feeding, and also interferes with development by inhibiting synthesis of the neuropeptide that triggers ecdysone release. The molecular targets mediating these effects are not known.

Toxicity evaluation

Azadirachtin is practically non-toxic to mammals, birds and plants. It is moderately toxic to aquatic invertebrates, but exposure is negligible due to low application rates and rapid degradation. Since it is only active by ingestion of treated foliage, exposure of non-target insects and honeybees is minimal.

Incompatibilities

Powder or liquid may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, reducing agents and metals, acid chlorides, alkalis, alkali metals, high heat, including sunlight.

Waste Disposal

Waste product may be disposed of onsite (open dumping may be prohibited) or at an approved waste disposal facility. All federal, state, and local environmental regulations must be observed.

Azadirachtin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Azadirachtin manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: Azadirachtin 11141-17-6
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-05

Hebei Mojin Biotechnology Co.,Ltd

Product: Azadirachta Indica Extract 11141-17-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2024-07-22

Hebei Mojin Biotechnology Co., Ltd

Product: Azadirachtin 11141-17-6
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-09-06

11141-17-6, AzadirachtinRelated Search:

INDACONITINE DECYL VINYL ETHER ISOAMYL TIGLATE (+)-METHYL (S)-3-HYDROXYPENTANOATE METHYL 2-HYDROXYDODECANOATE Methyl dimethoxyacetate 2-HYDROXYOCTADECANOIC ACID Dodecyl 2-methylacrylate METHYL 3-HYDROXYUNDECANOATE 15-METHYLHEXADECANOIC ACID Octadecyl vinyl ether DL-2-HYDROXYDECANOIC ACID METHYL ESTER Azadirachtin 2,2-Bis(hydroxymethyl)propionic acid METHYL 15-METHYLHEXADECANOATE TRIDECYL METHACRYLATE 4-Hydroxycyclohexanecarboxylic acid 1,11-Undecanedicarboxylic acid

AZADIRACHTIN B

AZATIN

AZATIN(R)

KAYNEEM

3-TIGLOYL-AZADIRACHTOL

AZADIRACHTIN, 10MG, NEAT

1H,7H-Naphtho1,8-bc:4,4a-cdifuran-5,10a(8H)-dicarboxylic acid, 10-(acetyloxy)octahydro-3,5-dihydroxy-4-methyl-8-(2E)-2-methyl-1-oxo-2-butenyloxy-4-(1aR,2S,3aS,6aS,7S,7aS)-3a,6a,7,7a-tetrahydro-6a-hydroxy-7a-methyl-2,7-methanofuro2,3-boxirenoeoxepin-1a(2H)

AZADIRACHTIN pure

AZADIRACTIN

PHEROTECH

Azadirachtin 10mg [11141-17-6]

Azaditrachtin

Nsc368675

AZADIRACHTIN A(P)

Azadirachtin Solution, 100ppm

NEEMOLIN

NEEMAZAD

NEEMAZAL

NEEMIX

AZAD

AZADIRACCHTIN A

AZADIRACHTIN

AZADIRACHTIN A

(2aR,3S,4S,4aR,5S,7aS,8S,10R,10aS,10bR)-10-(Acetyloxy)octahydro-3,5-dihydroxy-4-methyl-8-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]-4-[(1aR,2S,3aS,6aS,7S,7aS)-3a,6a,7,7a-tetrahydro-6a-hydroxy-7a-methyl-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl]-1H,7H-naphtho[1,8-bc:4,4a-c']difuran-5,10a(8H)-dicarboxylic acid 5,10a-dimethyl ester

Azatin EC

Azatin Magnum

Azatin XL

Ecozin

Gronim

NeemAzal F

NeemAzal T

NeemAzal W

Neemazol

Neemgold

Nimbicidine

Nimurin

Oikos

Oikos 25 plus

Oikos 323 Bio

Ornazin

Safer BioNEEM

Suneem

Superneem

(2aR,3S,4S,4aR,5S,7aS,8S,10R,10aS,10bR)-10-(Acetyloxy)octahydro-3,5-dihydroxy-4-Methyl-8-[[(2E)-2-Methyl-1-oxo-2-buten-1-yl]oxy]-4-[(1aR,2S,3aS,6aS,7S,7aS)-3a,6a,7,7a-tetrahydro-6a-hydroxy-7a-Methyl-2,7-Methanofuro[2,3-b]oxireno[e]oxepin-1a(2

1H,7H-Naphtho[1,8-bc:4,4a-c']difuran-5,10a(8H)-dicarboxylicacid,10-(acetyloxy)octahydro-3,5-dihydroxy-4-Methyl-8-[[(2E)-2-Methyl-1-oxo-2-buten-1-yl]oxy]-4-[(1aR,2S,3aS,6aS,7S,7aS)-3a,6a,7,7a-tetrahydro-6a-hydroxy-7a-Methyl-2,7-Methanofuro[2,3-b]oxireno[e]

Azadirachtin(Technical)

Azadirachtin @100 μg/mL in Methanol

1H,7H-Naphtho[1,8-bc:4,4a-c']difuran-5,10a(8H)-dicarboxylic acid, 10-(acetyloxy)octahydro-3,5-dihydroxy-4-methyl-8-[[(2E)-2-methyl-1-oxo-2-buten-1-yl]oxy]-4-[(1aR,2S,3aS,6aS,7S,7aS)-3a,6a,7,7a-tetrahydro-6a-hydroxy-7a-methyl-2,7-methanofuro[2,3-b]oxireno[e]oxepin-1a(2H)-yl]-, 5,10a-dimethyl ester, (...

Azadirachtin 100 μg/mL in Acetonitrile

Cypermethrin Impurity 8

Azadirachtin in Methanol

Azadirachtin A 100 μg/ml Acetonitrile

Azadirachtin-RM

11141-17-6

1141-17-6

C30H36O9

C35H44O16

Analytical Standards