GUANETHIDINE HEMISULFATE
- Product Name
- GUANETHIDINE HEMISULFATE
- CAS No.
- 60-02-6
- Chemical Name
- GUANETHIDINE HEMISULFATE
- Synonyms
- GUANETHIDINE SULFATE;guanethidine sulphate;Iporal;octadin;su-5864;Oktadin;octadine;Guethine;isobarin;nsc-29863
- CBNumber
- CB1309441
- Molecular Formula
- C10H22N4.1/2H2O4S
- Formula Weight
- 494.7
- MOL File
- 60-02-6.mol
GUANETHIDINE HEMISULFATE Property
- Melting point:
- 255-265°C
- Density
- 1.1052 (rough estimate)
- refractive index
- 1.7400 (estimate)
- storage temp.
- Hygroscopic, -20°C Freezer, Under Inert Atmosphere
- solubility
- Methanol (Slightly), Water (Slightly)
- form
- Solid
- color
- White
- Merck
- 4560
- Stability:
- Hygroscopic
- CAS DataBase Reference
- 60-02-6
Safety
- Safety Statements
- 24/25
- RTECS
- MF3240000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- G815000
- Product name
- GuanethidineHemisulfate
- Packaging
- 250mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- A8443
- Product name
- GuanethidineSulfate
- Packaging
- 1g
- Price
- $80
- Updated
- 2021/12/16
- Product number
- A8443
- Product name
- GuanethidineSulfate
- Packaging
- 5g
- Price
- $240
- Updated
- 2021/12/16
GUANETHIDINE HEMISULFATE Chemical Properties,Usage,Production
Chemical Properties
White Solid
Originator
Ismelin,Ciba,US,1960
Uses
Antihypertensive; antiglaucoma
Definition
ChEBI: A organic sulfate salt composed of two molecules of guanethidine and one of sulfuric acid.
Manufacturing Process
13.6 grams of chloroacetyl guanide is added while stirring to a solution of 22.6 grams of heptamethylene imine in 200 ml of benzene. After warming for 1 hour, and then cooling, the solution is filtered and the filtrate concentrated under reduced pressure. The residue, containing the 2-(1-N,N-heptamethylene-imino)-aceticacid guanide, is suspended in tetrahydrofuran and added to a refluxing solution of 6 grams of lithium aluminum hydride in tetrahydrofuran. After completion of the reaction, the excess of lithium aluminum hydride is decomposed by adding water, then aqueous sodium hydroxide. The solid material is filtered off, the filtrate is acidified with sulfuric acid and the 2-(1-N,N-heptamethylene-imino)-ethyl-guanidine sulfate can be recovered and recrystallized from aqueous ethanol, MP 276° to 281°C (with decomposition).
Therapeutic Function
Antihypertensive
GUANETHIDINE HEMISULFATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from GUANETHIDINE HEMISULFATE manufacturers
- Product
- guanethidine sulfate 60-02-6
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-26