Acebilustat
Description References- Product Name
- Acebilustat
- CAS No.
- 943764-99-6
- Chemical Name
- Acebilustat
- Synonyms
- ZK-322;ZK 322;CS-2501;CTX-4430;Acebilustat;ZK 322;ZK-322;Acebilustat(ZK322);Acebilustat,CTX-4430;Acebilustat USP/EP/BP;Acebilustat,Aminopeptidase,Inhibitor,inhibit,CTX 4430,CTX4430
- CBNumber
- CB13155056
- Molecular Formula
- C29H27N3O4
- Formula Weight
- 481.54
- MOL File
- 943764-99-6.mol
Acebilustat Property
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- Chloroform: slightly soluble; DMSO: slightly soluble; Methanol: slightly soluble
- form
- A crystalline solid
- CAS DataBase Reference
- 943764-99-6
N-Bromosuccinimide Price
- Product number
- A639379
- Product name
- Acebilustat
- Purity
- 99%
- Packaging
- 5mg
- Price
- $373
- Updated
- 2021/12/16
- Product number
- DC9986
- Product name
- Acebilustat(ZK322)
- Purity
- >98%
- Packaging
- 250mg
- Price
- $1200
- Updated
- 2021/12/16
- Product number
- DC9986
- Product name
- Acebilustat(ZK322)
- Purity
- >98%
- Packaging
- 1g
- Price
- $2500
- Updated
- 2021/12/16
Acebilustat Chemical Properties,Usage,Production
Description
Acebilustat (also known as CTX-4430) is a new once-daily oral anti-inflammatory drug in development for treatment of cystic fibrosis (CF) and other diseases. It is an inhibitor of leukotriene A4 hydrolase, which is responsible for the production of leukotriene B4 (LTB4). The later is a molecule that leads to inflammation. Therefore, Acebilustat can treat inflammation through suppressing the production of leukotriene B4.
References
https://www.cff.org/Trials/Pipeline/details/108/CTX-4430
Springman, E., et al. "127 Pharmacokinetic and pharmacodynamic profile of CTX-4430 in two phase 1 studies." Journal of Cystic Fibrosis14(2015):S90-S90.
Springman, E., et al. "126 A phase 1 clinical study of CTX-4430 in cystic fibrosis patients." Journal of Cystic Fibrosis 14(2015):S90-S90.
Elborn, J. S., et al. "Phase I Studies of Acebilustat: Pharmacokinetics, Pharmacodynamics, Food Effect, and CYP3A Induction." Clinical & Translational Science 10.1(2017):20-27.
Acebilustat Preparation Products And Raw materials
Raw materials
Preparation Products
Acebilustat Suppliers
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- China
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View Lastest Price from Acebilustat manufacturers
- Product
- Acebilustat 943764-99-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-10-16
- Product
- Acebilustat 943764-99-6
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-17