Acebilustat

Description References

Product Name: Acebilustat
CAS No.: 943764-99-6
Chemical Name: Acebilustat
Synonyms: ZK-322;ZK 322;CS-2501;CTX-4430;Acebilustat;ZK 322;ZK-322;Acebilustat(ZK322);Acebilustat,CTX-4430;Acebilustat USP/EP/BP;Acebilustat,Aminopeptidase,Inhibitor,inhibit,CTX 4430,CTX4430
CBNumber: CB13155056
Molecular Formula: C29H27N3O4
Formula Weight: 481.54
MOL File: 943764-99-6.mol

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Acebilustat Property

storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: Chloroform: slightly soluble; DMSO: slightly soluble; Methanol: slightly soluble
form: A crystalline solid
color: White to off-white
CAS DataBase Reference: 943764-99-6

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning

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N-Bromosuccinimide Price

Ambeed

Product number: A639379
Product name: Acebilustat
Purity: 99%
Packaging: 5mg
Price: $373
Updated: 2021/12/16

DC Chemicals

Product number: DC9986
Product name: Acebilustat(ZK322)
Purity: >98%
Packaging: 250mg
Price: $1200
Updated: 2021/12/16

DC Chemicals

Product number: DC9986
Product name: Acebilustat(ZK322)
Purity: >98%
Packaging: 1g
Price: $2500
Updated: 2021/12/16

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Acebilustat Chemical Properties,Usage,Production

Description

Acebilustat (also known as CTX-4430) is a new once-daily oral anti-inflammatory drug in development for treatment of cystic fibrosis (CF) and other diseases. It is an inhibitor of leukotriene A4 hydrolase, which is responsible for the production of leukotriene B4 (LTB4). The later is a molecule that leads to inflammation. Therefore, Acebilustat can treat inflammation through suppressing the production of leukotriene B4.

References

https://www.cff.org/Trials/Pipeline/details/108/CTX-4430
Springman, E., et al. "127 Pharmacokinetic and pharmacodynamic profile of CTX-4430 in two phase 1 studies." Journal of Cystic Fibrosis14(2015):S90-S90.
Springman, E., et al. "126 A phase 1 clinical study of CTX-4430 in cystic fibrosis patients." Journal of Cystic Fibrosis 14(2015):S90-S90.
Elborn, J. S., et al. "Phase I Studies of Acebilustat: Pharmacokinetics, Pharmacodynamics, Food Effect, and CYP3A Induction." Clinical & Translational Science 10.1(2017):20-27.

Acebilustat Preparation Products And Raw materials

Raw materials

Preparation Products

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Acebilustat Suppliers

China 51 United States 11 Global 62

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 52925
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38632
Advantage: 58

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

United States Biological

Tel: --
Fax: --
Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

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View Lastest Price from Acebilustat manufacturers

Hebei Yanxi Chemical Co., Ltd.

Product: Acebilustat 943764-99-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 20tons
Release date: 2023-10-16

Dideu Industries Group Limited

Product: Acebilustat 943764-99-6
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-08-17

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Acebilustat USP/EP/BP

Acebilustat,Aminopeptidase,Inhibitor,inhibit,CTX 4430,CTX4430

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Acebilustat,CTX-4430

943764-99-6