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R-IMPP

Product Name
R-IMPP
CAS No.
2133832-83-2
Chemical Name
R-IMPP
Synonyms
R-IMPP;PF-00932239 (R-IMPP);Benzenepropanamide, N-1-isoquinolinyl-4-methoxy-N-(3R)-3-piperidinyl-;(R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide;Serine endopeptidases,PF-00932239,PF 00932239,inhibit,Ser/Thr Protease,RIMPP,R-IMPP,Inhibitor,Threonine proteases,R IMPP,PF00932239,Serine proteases
CBNumber
CB13155117
Molecular Formula
C24H27N3O2
Formula Weight
389.49
MOL File
2133832-83-2.mol
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R-IMPP Property

Boiling point:
594.4±50.0 °C(Predicted)
Density 
1.186±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 1 mg/ml; DMSO: 10 mg/ml
form 
A crystalline solid
pka
9.14±0.10(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
20861
Product name
(R)-IMPP
Packaging
1mg
Price
$73
Updated
2024/03/01
Cayman Chemical
Product number
20861
Product name
(R)-IMPP
Packaging
25mg
Price
$1075
Updated
2024/03/01
Cayman Chemical
Product number
20861
Product name
(R)-IMPP
Packaging
5mg
Price
$288
Updated
2024/03/01
Cayman Chemical
Product number
20861
Product name
(R)-IMPP
Packaging
10mg
Price
$539
Updated
2024/03/01
ChemScene
Product number
CS-7579
Product name
R-IMPP
Purity
99.36%
Packaging
50mg
Price
$680
Updated
2021/12/16
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R-IMPP Chemical Properties,Usage,Production

Description

(R)-IMPP is a cell-permeable inhibitor of the secretion of proprotein convertase subtilisin/kexin type 9 (PCSK9; IC50 = 4.8 μM). It promotes the uptake of LDL cholesterol in hepatoma cells by increasing LDL receptor levels. (R)-IMPP apparently impairs PCSK9 secretion by causing transcript-dependent inhibition of PCSK9 translation.

R-IMPP Preparation Products And Raw materials

Raw materials

Preparation Products

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R-IMPP Suppliers

China 28 India 1 United States 7 Global 36
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
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58
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
5926
Advantage
55
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ：65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
7298
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58
Medi-tech Bioscientific Co., Ltd.
Tel
0519-83246372 13585352506
Fax
0519-83246372
Country
China
ProdList
1844
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58
Angel Pharmatech, Ltd.
Tel
17317130613
Fax
QQ3358272972
Email
3358272972@qq.com
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China
ProdList
3254
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58
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-037163312495,13303845143 13303845143
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QQ3001379618
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3001379618@qq.com
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China
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10376
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58
Guangzhou Tomums Life Science Co., Ltd.
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020-31155029 18902330969
Fax
020-31155029
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sales@tomums.cn
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China
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Shanghai Dongyang Biotechnology Co., Ltd.
Tel
0512-0512-13601744364 13601744364
Email
chemsharker@126.com
Country
China
ProdList
927
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58
DC Chemicals
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
ProdList
9409
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58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
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11218
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58
Shanghai Zeye Biotechnology Co., Ltd.
Tel
021-61998551 13122364865
Email
sale1@shzysw.net
Country
China
ProdList
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58
Absin Bioscience Inc.
Tel
021-38015121 15000105423
Email
wulan@absin.cn
Country
China
ProdList
24731
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58
Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
Country
China
ProdList
5132
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Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44806
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58
Abmole Bioscience Inc.
Tel
021-50967598 02150967598
Email
sales@abmole.cn
Country
China
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4494
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Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29774
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ChemeGen 中国
Tel
18818260767
Fax
QQ 3610331285
Email
2625930290@qq.com
Country
China
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6973
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58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
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62075
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58
Kaifeng Mingren Pharmaceutical Co.,LTD
Tel
0371-65741762
Fax
QQ：2860768577
Email
sales@hasunny.com
Country
China
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2380
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58
InvivoChem
Tel
13549236410
Email
sales@invivochem.cn
Country
China
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6753
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58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24644
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58
Shanghai Aladdin Biochemical Technology Co.,Ltd.
Tel
+86-18521732826
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market@aladdin-e.com
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China
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48461
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58
Hubei wei shi reagent group ltd., company
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027-02759101766 13125137661
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2853877621@qq.com
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China
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6104
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ATK CHEMICAL COMPANY LIMITED
Tel
+undefined-21-51877795
Fax
+86 21 5161 9052/ 5187 7796
Email
ivan@atkchemical.com
Country
China
ProdList
32956
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60
SHANGHAI KEAN TECHNOLOGY CO., LTD.
Tel
+8613817748580
Fax
021-50175322
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cooperation@kean-chem.com
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China
ProdList
40066
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58
Shanghai Acmec Biochemical Technology Co., Ltd.
Tel
+undefined18621343501
Email
product@acmec-e.com
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China
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33338
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58
Shanghai Jingke Chemical Technology Co., Ltd.
Tel
--
Fax
--
Email
jingkehuaxue@163.com
Country
CHINA
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6972
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58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
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Email
info@zzsrm.com
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CHINA
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6650
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58

2133832-83-2, R-IMPPRelated Search:


  • R-IMPP
  • Benzenepropanamide, N-1-isoquinolinyl-4-methoxy-N-(3R)-3-piperidinyl-
  • PF-00932239 (R-IMPP)
  • (R)-N-(Isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide
  • Serine endopeptidases,PF-00932239,PF 00932239,inhibit,Ser/Thr Protease,RIMPP,R-IMPP,Inhibitor,Threonine proteases,R IMPP,PF00932239,Serine proteases
  • 2133832-83-2